Results 71 to 80 of about 622,957 (315)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
npj Computational Materials, 2023 A desired prerequisite when performing a quantum mechanical calculation is to have an initial idea of the atomic positions within an approximate crystal structure. The atomic positions combined should result in a system located in, or close to, an energy
Adam Carlsson +2 more
doaj +1 more source
Crystal Structures of New Ivermectin Pseudopolymorphs
Crystals, 2021 New pseudopolymorphs of ivermectin (IVM), a potential anti-COVID-19 drug, were prepared. The crystal structure for three pseudopolymorphic crystalline forms of IVM has been determined using single-crystal X-ray crystallographic analysis.
Kirill Shubin +2 more
doaj +1 more source
Crystal Structure Of Bis(acetylacetonato)bis(quinoline)nickel(ii), Ni(c5h14o2n)2(c9h 7n)2
, 2015 C28H28N2NiO4, triclinic, P1̄ (no. 2), a = 7.9202(6) Å, b = 8.0496(6) Å, c = 10.246(1) Å, α = 97.15(1)°, β = 106.68(1)°, γ = 94.686(9)°, V = 616.1 Å3, Z = 1, Rgt(F) = 0.028, wRref(F2) = 0.078, T = 293 K.
Dunstan P.O. +4 more
core +1 more source
Structure of the World Crystal [PDF]
Australian Journal of Physics, 1998 Identifying space with a superconducting cosmic dust, the structure of the ‘world crystal’ is built. Particles moving on open geodesics are assimilated with the ‘electron gas’ in a lattice, and those moving on closed geodesics with nodes of the same lattice.
Agop, M +6 more
openaire +2 more sources
Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Crystal structures of human procathepsin H. [PDF]
PLoS ONE, 2018 Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases.
Yue Hao +8 more
doaj +1 more source
Systematic studies of crystal structures under non-ambient conditions [PDF]
, 2004 Variable temperature single crystal X-ray diffraction analysis has been used to study four molecular systems: 4-(p-trlfluoromethyl phenylethynyl) prefluorotoluene (1), 2-methyl-4-(4-trifluoromethyl-phenyl) but-3-yn-2-ol (2), phenylethynyl ...
Smith, Philip S.
core
Mechanism Design with Singularity Avoidance of Crystal-Inspired Deployable Structures
, 2019 Although deployable structures have important applications in various fields, developing a new form of structural configuration faces some scientific challenges.
Jian Feng, Yao Chen, Jiayi Yan
core +1 more source
Crystal structure of mandipropamid [PDF]
Acta Crystallographica Section E Crystallographic Communications, 2015 In the title compound, C23H22ClNO4(systematic name: (RS)-2-(4-chlorophenyl)-N-{2-[3-methoxy-4-(prop-2-yn-1-yloxy)phenyl]ethyl}-2-(prop-2-ynyloxy)acetamide), an amide fungicide, the dihedral angle between the chlorobenzene and benzene rings is 65.36 (6)°.
Hyunjin Park +3 more
openaire +3 more sources