Results 11 to 20 of about 670,872 (365)
Computational Crystallization [PDF]
Crystallization is a key step in macromolecular structure determination by crystallography. While a robust theoretical treatment of the process is available, due to the complexity of the system, the experimental process is still largely one of trial and ...
Altan, Irem+2 more
core +3 more sources
In this work, solubility data of 1,5-pentanediamine adipate dihydrate in binary solvent systems of water + methanol, water + ethanol and water + N,N-dimethylformamide were experimentally measured via a static gravimetric method in the temperature range ...
Liang Li+8 more
doaj +1 more source
Enhancement of Crystallization Process of the Organic Pharmaceutical Molecules through High Pressure
The enhancement of the crystallization process through high pressures was studied by using ribavirin (RVB) as a model compound. The effects of high pressure on crystallization thermodynamics, nucleation kinetics, and process yield were evaluated and ...
Yaoguang Feng+5 more
doaj +1 more source
Water confined or constrained in a cellular environment can exhibit a diverse structural and dynamical role and hence will affect the self-assembly behavior of biomolecules.
Qi Liu+6 more
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The Effect of Solvents on the Crystal Morphology of Pyriproxyfen
To obtain crystal products with ideal morphology and better quality, it is important to fully understand and grasp the affecting mechanism of solvents on crystal morphology.
Xiaoyang Yan+7 more
doaj +1 more source
Molecular tectonics: from crystals to crystals of crystals [PDF]
The in situ combination of M(II) cations (Co, Ni, Cu or Zn) with 2,4,6-pyridinetricarboxylic acid as a ligand, a bisamidinium dication as a H-bond donor tecton and NaOH leads to the formation of anionic metal complexes ML2(2-) and their interconnection into isomorphous 3D H-bonded networks displaying different colours which were used as preformed seed ...
Marinescu, Gabriela+3 more
openaire +4 more sources
Impact of Impurities on Crystallization and Product Quality: A Case Study with Paracetamol
A thorough, systematic study into the effect that structurally related impurities have on both the process and product quality during the crystallization of an active pharmaceutical ingredient is presented.
Stephanie J. Urwin+3 more
doaj +1 more source
Targeting Desired Particle Size for Improved Dissolution and Manufacturability of Mefenamic Acid
This work aims at the production of uniformly sized, equant shaped crystals using a direct nucleation control (DNC) strategy to help achieve enhanced manufacturability and bioavailability of the active pharmaceutical ingredients (API).
Wei Li, Chris D. Rielly, Brahim Benyahia
doaj +1 more source
Gypsum Seeding to Prevent Scaling
Eutectic freeze crystallization (EFC) is a novel separation technique that can be applied to treat brine solutions such as reverse osmosis retentates. These are often a mixture of different inorganic solutes. The treatment of calcium sulphate-rich brines
Taona Malvin Chagwedera+2 more
doaj +1 more source