Results 101 to 110 of about 287,848 (276)

1-(2,4-Dinitrophenyl)-2-[(E)-(3,4,5-trimethoxybenzylidene)]hydrazine

Acta Crystallographica Section E, 2014
Molecules of the title compound, C16H16N4O7, are not planar with a dihedral angle of 5.50 (11)° between the substituted benzene rings. The two meta-methoxy groups of the 3,4,5-trimethoxybenzene moiety lie in the plane of the attached ring [Cmethyl–O–C–C ...
Suchada Chantrapromma, Pumsak Ruanwas, Nawong Boonnak, C. S. Chidan Kumar, Hoong-Kun Fun   +4 more
doaj   +1 more source

From Strain to Pressure: Atomically Resolved Mechanisms of Stress Dissipation in Emissive, Elastically Deformable Molecular Crystals Under Ambient and High Pressure

Advanced Optical Materials, EarlyView.
Molecular crystals must withstand both isotropic and anisotropic stress to function in flexible optoelectronics and high‐pressure devices. In situ high‐pressure single‐crystal X‐ray diffraction coupled with DFT‐D computations reveal how an emissive molecular crystal with interdigitated packing bends elastically at ambient‐pressure and remains ...
Arif H. Dar, Vikram C. Joshi, Alexandra Longcake, Tamador Alkhidir, Ayat Al Nimer, Praveen B. Managutti, Shamraiz H. Talib, Jaime Viegas, Michael R. Probert, Changquan C. Sun, Sharmarke Mohamed   +10 more
wiley   +1 more source

(E)-2-[4-(Diethylamino)styryl]-1-methylquinolin-1-ium 4-chlorobenzenesulfonate monohydrate

Acta Crystallographica Section E, 2014
The asymmetric unit of the title hydrated salt, C22H25N2+·C6H4ClO3S−·H2O, comprises two 2-[4-(diethylamino)styryl]-1-methylquinolin-1-ium cations, two 4-chlorobenzenesulfonate anions and two solvent water molecules.
Suchada Chantrapromma, Narissara Kaewmanee, Nawong Boonnak, Ching Kheng Quah, Hoong-Kun Fun   +4 more
doaj   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

Advanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du, Eun Seo Bae, Thinh T. M. Bui, Seok Beom Lee, Dahan Kim, Jin‐Gyeong Park, Yongjoo Park, Soo Yeon Park, Sangwook Kang, Beomsu Lee, Daniel Shin, Yun Pyo Kang, In‐Gyun Lee, Dae‐Duk Kim, Seokhee Kim, Suckchang Hong, Kyuho Moon, Sang Kook Lee, Dong‐Chan Oh   +18 more
wiley   +1 more source

(E)-4-Methoxy-N′-(2,4,5-trimethoxybenzylidene)benzohydrazide hemihydrate

Acta Crystallographica Section E, 2014
The title compound crystallizes as a hemihydrate, C18H20N2O5·0.5H2O. The molecule exists in an E conformation with respect to the C=N imine bond. The 4-methoxyphenyl unit is disordered over two sets of sites with a refined occupancy ratio of 0.54 (2):0 ...
Suchada Chantrapromma, Nawong Boonnak, Jirapa Horkaew, Ching Kheng Quah, Hoong-Kun Fun   +4 more
doaj   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

(E)-1-(2,4-Dinitrophenyl)-2-(3-ethoxy-4-hydroxybenzylidene)hydrazine

Acta Crystallographica Section E, 2014
The molecule of the title hydrazine derivative, C15H14N4O6, is essentially planar, the dihedral angle between the substituted benzene rings being 2.25 (9)°. The ethoxy and hydroxy groups are almost coplanar with their bound benzene ring [r.m.s. deviation
Hoong-Kun Fun, Suchada Chantrapromma, Pumsak Ruanwas, Thawanrat Kobkeatthawin, C. S. Chidan Kumar   +4 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Deprotonative C(sp3)/C(sp2)–H (Multi)Silylation of (Hetero)Arenes Mediated by NaTMP

Angewandte Chemie, EarlyView.
An operationally simple protocol using a strongly basic sodium amide in combination with sterically emcumbered silicon electrophiles enables the deprotonative C–H (multi)silylation of a myriad of (hetero)arenes. Mechanistic investigations highlight the pivotal role of steric and coordination effects in controlling the regioselectivity and efficiency of
David Sánchez‐Roa, Sophia Belrhomari, Ana McGinley, Clevin Anto Liju, Manting Mu, Max García‐Melchor, Eva Hevia   +6 more
wiley   +2 more sources