Results 131 to 140 of about 6,874,902 (263)

Mineralogical Crystallography Volume III

The United Nations and UNESCO designated 2014 as the International Year of Crystallography, in which the scientific community celebrated the centenary of the discovery of X-ray diffraction [...
Vladislav V. Gurzhiy
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Crystallographic and computational studies of organic non-linear optical materials [PDF]

, 2007
This thesis presents work on the determination of both linear and non-linear optical properties of organic molecular crystals from high-resolution X-ray diffraction data.
Turner, Michael James
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Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

Angewandte Chemie, EarlyView.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey, D. M. Nirosh Udayanga, Huanchun Zhang, Roshan Katekar, Wei Xie, Shreya M. Ravichandran, Xinyong Cai, Zachary C. Lorson, William M. McFadden, Won Hee Ryu, Jiashu Xie, Karen A. Kirby, Stefan G. Sarafianos, Zhengqiang Wang   +13 more
wiley   +2 more sources

X-Ray Vision, Crystallography

This site features a tutorial designed to allow students to gain an appreciation of how X-ray crystallography works. Using X-ray diffraction patterns to determine the arrangement of atoms in a molecule requires sophisticated mathematics.

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The Bayesian Statistical Approach to the Phase Problem in Protein X-ray Crystallography [PDF]

, 1999
We review a Bayesian statistical approach to the phase problem in protein X-ray crystallography. We discuss the mathematical foundations and the computational issues. The introduction to the theory and the algorithms does not require strong background in
Phillips, George, Zhang, Yin, Tapia, Richard, Wu, Zhijun   +3 more
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Nanoflow electrospinning serial femtosecond crystallography

, 2012
An electrospun liquid microjet has been developed that delivers protein microcrystal suspensions at flow rates of 0.14-3.1 µl min(-1) to perform serial femtosecond crystallography (SFX) studies with X-ray lasers.
Zouni, Athina, Gildea, Richard J, Sokaras, Dimosthenis, Yachandra, Vittal K., Sierra, Raymond G, White, William E., Hattne, Johan, Glatzel, Pieter, Milathianaki, Despina, Weng, Tsu-Chien, Schafer, Donald W, Seibert, M. Marvin, Alonso-Mori, Roberto, Bergmann, Uwe, Kern, Jan, Messinger, Johannes, Sierra, Raymond G., Seibert, M Marvin,, Zwart, Petrus H, Messerschmidt, Marc M, Hampton, Christina Y., Grosse-Kunstleve, Ralf W, Grosse-Kunstleve, Ralf W., Adams, Paul D., Yachandra, Vittal K, Miahnahri, Alan, Schafer, Donald W., Sauter, Nicholas K., Sellberg, Jonas,, McQueen, Trevor A., Boutet, Sébastien, Starodub, Dmitri, Tran, Rosalie, Bogan, Michael J, Gildea, Richard J., Adams, Paul D, Zwart, Petrus H., Lassalle-Kaiser, Benedikt, Messerschmidt, Marc M., Bogan, Michael J., Messinger, Johannes,, Echols, Nathaniel, Hampton, Christina Y, Williams, Garth J, Sellberg, Jonas, Seibert, M Marvin, Laksmono, Hartawan, Yano, Junko, Gloeckner, Carina, McQueen, Trevor A, Loh, N Duane, Loh, N. Duane, Weng, Tsu Chien, Fry, Alan R, Fry, Alan R., Hellmich, Julia, Williams, Garth J., White, William E, Sauter, Nicholas K, Glöckner, Carina   +59 more
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Characterisation of very thin epitaxial layers by high resolution x-ray diffraction [PDF]

, 1989
X-rays can be used as a sensitive, non-destructive probe for the characterisation of semiconductors. The energy and wavelength of X-rays is such that structural information down to the Ảngstrom level can be yielded with a depth penetration of several ...
Miles, S.J, Miles, Simon Jonathon
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Extending Small‐Molecule Aptamer Discovery Principles to Protein Targets: Selection and Characterization of Green Fluorescent Protein Aptamers

Angewandte Chemie, EarlyView.
Protein‐binding aptamers remain poorly understood compared to their small‐molecule counterparts. Using green fluorescent protein (GFP) variants as a tractable model system, we show how subtle changes in protein surface composition and divalent metal ions reshape aptamer selection, specificity, and binding.
Stefen Stangherlin, Nathan Wong, Logan Fanning, Kate Kim, Peter Kim, Iffat Tabassum, Songyang Miao, Rui Huang, Juewen Liu   +8 more
wiley   +2 more sources

Switching ATP‐Forming Phosphoryl‐Transfer Chemistry With a Restricted Set of Amino Acids

Angewandte Chemie, EarlyView.
Constraints on amino acid composition relevant to prebiotic chemistry reshape enzyme chemistry by replacing the canonical mechanism within a conserved protein fold with a distinct ATP‐forming reaction, ADP disproportionation. Such constraints generate alternative catalytic solutions not observed in modern enzymes and point to chemically plausible early
Sota Yagi, Subrata Dasgupta, Shunsuke Tagami, Satoshi Akanuma   +3 more
wiley   +2 more sources

X-ray-induced photo-chemistry and X-ray absorption spectroscopy of biological samples

, 2012
As synchrotron light sources and optics deliver greater photon flux on samples, X-ray-induced photo-chemistry is increasingly encountered in X-ray absorption spectroscopy (XAS) experiments.
J. Aitken (23358079), I. Pickering (23316769), G. George (3451616), K. Hodgson (23404759), C. Glover (23404765), B. Hedman (23404756), P. Lay (23301673), M. Jake Pushie (23404747), Mark Hackett (23289835), A. Levina (23404762), K. Nienaber (23404750), I. Ascone (23404753)   +11 more
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