Results 181 to 190 of about 2,487,426 (273)

Quantifying optical scattering losses in pump-probe serial femtosecond crystallography experiments. [PDF]

IUCrJ
Barends TRM, Gorel A, Niziński S, Appleby MV, Kloos M, Nagano S, Hilpert M, Dworkowski F, Cirelli C, Beale EV, Hartmann E, Bacellar C, Shoeman RL, Doak RB, Beale JH, Johnson PJM, Schlichting I.   +16 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

Angewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon, Vivek K. Mishra, Mingming Zhao, Konrad Büssow, Alexander Popoff, Chengzhang Fu, Rolf Müller, Lothar Jänsch, Wulf Blankenfeldt, Mark Brönstrup   +9 more
wiley   +1 more source

Metalloproteins in an Era of Modern Crystallography and Why the Beamline Matters. [PDF]

Synchrotron Radiat News
Maggiolo AO, Cohen AE.
europepmc   +1 more source

HDX-MS Detects Steric Protection and Trimeric Compaction of TNFα after It Binds Receptors or Antibodies. [PDF]

ACS Omega
Haynes CA, Keppel TR, Osman SH, Mekonnen B, Baudys J, Woolfitt AR, Barr JR, Wang D.   +7 more
europepmc   +1 more source

Best practices for cryo-trapping time-resolved crystallography with the Spitrobot crystal plunger. [PDF]

Protein Sci
Bosman R, Hatton CE, Prester A, Spiliopoulou M, Apostolopoulou V, Tellkamp F, Mehrabi P, Schulz EC.   +7 more
europepmc   +1 more source

Gas-controlled capillary spinner for time-resolved powder X-ray diffraction under dynamic conditions. [PDF]

J Appl Crystallogr
Kawaguchi S, Takemoto M, Kobayashi S, Kubota Y.   +3 more
europepmc   +1 more source

Advancing beam shaping from visible light to X-rays for synchrotron applications. [PDF]

Sci Rep
Khosroabadi H, Romano P, Alianelli L, Brandao-Neto J, Flaig R, Sawhney K.   +5 more
europepmc   +1 more source

An integrated experimental and computational pipeline for crystallographic fragment screening of membrane protein in the lipid cubic phase. [PDF]

Commun Chem
Huang CY, Cheng R, Metz A, Bucher D, Andres F, Bacchin A, Glover H, Sager CP, Wang M, Steinmetz MO, Hennig M, Sharpe M.   +11 more
europepmc   +1 more source

TPEN-Advanced Metal Chelator: From Characterization to Biomedical Applications. [PDF]

Molecules
Rydel-Ciszek K.
europepmc   +1 more source