Results 11 to 20 of about 2,487,426 (273)

Automatic processing of macromolecular crystallography X-ray diffraction data at the ESRF. [PDF]

J Appl Crystallogr, 2013
A system for the automatic reduction of single- and multi-position macromolecular crystallography data is presented.
Monaco S, Gordon E, Bowler MW, Delagenière S, Guijarro M, Spruce D, Svensson O, McSweeney SM, McCarthy AA, Leonard G, Nanao MH.   +10 more
europepmc   +2 more sources

A century of X-ray crystallography and 2014 international year of X-ray crystallography

Macedonian Journal of Chemistry and Chemical Engineering, 2015
The 100th anniversary of the Nobel prize awarded to Max von Laue in 1914 for his discovery of diffraction of X-rays on a crystal marked the beginning of a new branch of science - X-ray crystallography.
Biserka Kojić-Prodić
doaj   +4 more sources

Comparative assessment of crystallographic and cryo-EM models in the Protein Data Bank. [PDF]

FEBS Open Bio
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Wlodawer A, Rubach P, Dauter Z, Dec W, Brzezinski D, Kulik M, Minor W, Jaskolski M.   +7 more
europepmc   +2 more sources

The Photovoltaic Performance of Sensitizers for Organic Solar Cells Containing Fluorinated Chalcones with Different Halogen Substituents

Crystals, 2021
Two newly halogenated chalcones, derivatives of C15H10ClFO (CH-ClF) and C15H10F2O (CH-FF), were synthesized using the Claisen–Schmidt condensation method.
Siti Nabilla Aliya Mohd Nizar, Siti Noor Farhana Ab Rahman, Muhamad Fikri Zaini, Ainizatul Husna Anizaim, Ibrahim Abdul Razak, Suhana Arshad   +5 more
doaj   +1 more source

The current role and evolution of X-ray crystallography in drug discovery and development

Expert Opinion on Drug Discovery, 2023
Introduction Macromolecular X-ray crystallography and cryo-EM are currently the primary techniques used to determine the three-dimensional structures of proteins, nucleic acids, and viruses.
Vanessa Bijak, Michal Szczygiel, J. Lenkiewicz, Michael Gucwa, D. Cooper, K. Murzyn, W. Minor   +6 more
semanticscholar   +1 more source

Chemical crystallography by serial femtosecond X-ray diffraction

Nature, 2022
Inorganic–organic hybrid materials represent a large share of newly reported structures, owing to their simple synthetic routes and customizable properties1.
Elyse A. Schriber, D. Paley, R. Bolotovsky, D. Rosenberg, R. Sierra, A. Aquila, D. Mendez, F. Poitevin, Johannes P. Blaschke, A. Bhowmick, Ryan P. Kelly, M. Hunter, Brandon Hayes, Derek C. Popple, Matthew Yeung, Carina Pareja‐Rivera, Carina Pareja-Rivera, S. Lisova, K. Tono, M. Sugahara, S. Owada, T. Kuykendall, K. Yao, P. Schuck, Diego Solís-Ibarra, N. Sauter, A. Brewster, J. Hohman   +27 more
semanticscholar   +1 more source

Structure determination of GPCRs: cryo-EM compared with X-ray crystallography

Biochemical Society Transactions, 2021
G protein-coupled receptors (GPCRs) are the largest single family of cell surface receptors encoded by the human genome and they play pivotal roles in co-ordinating cellular systems throughout the human body, making them ideal drug targets.
J. García-Nafría, C. G. Tate
semanticscholar   +1 more source

Molecular interactions at the colchicine binding site in tubulin: an X-ray crystallography perspective

Drug Discovery Today, 2021
Tubulin is an important cancer drug target. Compounds that bind at the colchicine site in tubulin have attracted significant interest as they are generally less affected by multidrug resistance than are other potential drugs.
Jiaxing Wang, Duane D. Miller, Wei Li
semanticscholar   +1 more source

(E)-1-(Benzo[d][1,3]dioxol-5-yl)-3-([2,2′-bithiophen]-5-yl)prop-2-en-1-one: crystal structure, UV–Vis analysis and theoretical studies of a new π-conjugated chalcone

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C18H12O3S2, synthesized by the Claisen–Schmidt condensation method, the essentially planar chalcone unit adopts an s-cis configuration with respect to the carbonyl group within the ethylenic bridge.
Ainizatul Husna Anizaim, Muhamad Fikri Zaini, Muhammad Adlan Laruna, Ibrahim Abdul Razak, Suhana Arshad   +4 more
doaj   +1 more source

Structural, Hirshfeld and DFT studies of conjugated D–π–A carbazole chalcone crystal

Acta Crystallographica Section E: Crystallographic Communications, 2020
A new conjugated carbazole chalcone compound, (E)-3-[4-(9,9a-dihydro-8aH-carbazol-9-yl)phenyl]-1-(4-nitrophenyl)prop-2-en-1-one (CPNC), C27H18N2O3, was synthesized using a Claisen–Schmidt condensation reaction.
Muhamad Fikri Zaini, Ibrahim Abdul Razak, Wan Mohd Khairul, Suhana Arshad   +3 more
doaj   +1 more source