Results 41 to 50 of about 6,874,902 (263)

Large-angle convergent-beam setup for femtosecond X-ray crystallography

, 2003
International audienceIt is demonstrated how femtosecond plasma X-ray sources can be used to record X-ray diffraction images with many simultaneous reflections.
Uschmann, I., Boschetto, Davide, Fourmaux, S., Rousse, Antoine, Hulin, D., Perez, J., Förster, E., Rischel, Christian   +7 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

The crystal structure of zwitterionic 2-{[(4-iminiumyl-3-methyl-1,4-dihydropyridin-1-yl)methyl]carbamoyl}benzoate hemihydrate

Acta Crystallographica Section E: Crystallographic Communications, 2017
The asymmetric unit of the title compound, C15H15N3O3·0.5H2O, comprises two 2-{[(4-iminiumyl-3-methyl-1,4-dihydropyridin-1-yl)methyl]carbamoyl}benzoate zwitterions (A and B) and a water molecule.
C. S. Chidan Kumar, Ai Jia Sim, Weng Zhun Ng, Tze Shyang Chia, Wan-Sin Loh, Huey Chong Kwong, Ching Kheng Quah, S. Naveen, N. K. Lokanath, Ismail Warad   +9 more
doaj   +1 more source

X-ray lasers and serial crystallography [PDF]

, 2015
: It is now more than five years since protein crystallography data were first collected using a free-electron X-ray laser (XFEL), so it seems an appropriate time for an evaluation of this method of `serial femtosecond crystallography' (SFX) and its ...

core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Crystal structure and Hirshfeld surface analysis of a chalcone derivative: (E)-3-(4-fluorophenyl)-1-(4-nitrophenyl)prop-2-en-1-one

Acta Crystallographica Section E: Crystallographic Communications, 2019
The molecular structure of the title chalcone derivative, C15H10FNO3, is nearly planar and the molecule adopts a trans configuration with respect to the C=C double bond.
Qin Ai Wong, Tze Shyang Chia, Huey Chong Kwong, C. S. Chidan Kumar, Ching Kheng Quah, Md. Azharul Arafath   +5 more
doaj   +1 more source

A simple adaptation to a protein crystallography station to facilitate difference X-ray scattering studies

, 2019
The X-ray crystallography station I911-2 at MAXLab II (Lund, Sweden) has been adapted to enable difference small- and wide-angle X-ray scattering (SAXS/WAXS) data to be recorded.
Sjöhamn, Jennie, Hammarin, Greger,, Appio, Roberto,, Harimoorthy, Rajiv,, Berntsen, Peter,, Sjöhamn, Jennie,, Sharma, Amit, Neutze, Richard, Sharma, Amit,, Appio, R., Björling, Alexander, Järvå, Michael,, Harimoorthy, Rajiv, Brändén, Gisela,, Järvå, Michael, Appio, Roberto, Hammarin, Greger, Berntsen, Peter, Björling, Alexander,, Lund University., Westenhoff, Sebastian, Brändén, Gisela, Westenhoff, Sebastian,, Neutze, Richard,   +23 more
core   +1 more source

Ag on Ge(111): 2D X-ray structure analysis of the (Wurzel)3 x (Wurzel)3 superstructure [PDF]

, 1992
We have studied the Ag/Ge(111)(Wurzel)3 x (Wurzel)3 superstructure by grazing-incidence X-ray diffraction. In our structural analysis we find striking similarities to the geometry of Au on Si(111). The Ag atoms form trimer clusters with an Ag-Ag distance
Johnson, Robert L., Le Lay, Guy, Johnson, R. L., Le Lay, G., Grey, F., Feidenhans'l, Robert, Feidenhans'l, R., Dornisch, D., Lay, G. le, Feidenhans'l, Robert Krarup, Johnson, R.L., Schulz, H., Moritz, Wolfgang, Nielsen, M., Nielsen, Morten, Moritz, W.   +15 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

N-{(Z)-3-Oxo-3-[(E)-(pyridin-2-ylmethyl)diazenyl]-1-(thiophen-2-yl)prop-1-en-2-yl}benzamide

IUCrData, 2016
In the title compound, C20H16N4O2S, the thiophene ring subtends dihedral angles of 58.6 (3) and 9.8 (3)° with the benzamide and pyridine rings, respectively, whereas these two rings are inclined to one another by 59.3 (3)°. There is an intramolecular C—H.
Devinder K. Sharma, K. N. Subbulakshmi, B. Narayana, B. K. Sarojini, Sumati Anthal, Rajni Kant   +5 more
doaj   +1 more source