Results 221 to 230 of about 287,848 (276)

Isolation and Structural Characterization of Se‐Hügerschoff Intermediates Derived From 4‐Bromoaniline

Journal of Heterocyclic Chemistry, EarlyView.
Isolation and characterization of Se‐brominated Hügerschoff intermediates enable structural and mechanistic insight into seleno‐Hügerschoff cyclization to 2‐aminobenzoselenazoles. ABSTRACT A brominated intermediate within the Hügerschoff reaction has long been postulated but never directly observed.
Adam W. E. Stewart, Tom Fellows, Lucy Li, Craig J. Morton, Glen P. Carter, Jonathan M. White   +5 more
wiley   +1 more source

Teaching Undergraduates X‑ray Crystallography with Porphyrins

ACS Omega
Asa Toombs, Michelle De La Cruz, Luke Van Hoosen, Zoe Y. Marr, Morgan Redington, Eva Zurek, Joyce Pham   +6 more
doaj   +1 more source

Serendipitous discovery of an allosteric inhibitor binding groove in the proline biosynthetic enzyme pyrroline-5-carboxylate reductase 1. [PDF]

Biochem J
Meeks KR, Mattingly CJ, Nix JC, Chuk O, Protopopov MV, Tarkhanova OO, Tanner JJ.   +6 more
europepmc   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

X-ray Crystallography Laboratory

, 2023
Purdue University Office of Research, Zeller, Matthias   +1 more
openaire   +1 more source

Korea-Japan Biophysics Collaboration: A journey through microbial rhodopsin research. [PDF]

Biophys Physicobiol
Park JH.
europepmc   +1 more source

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Speciation, Structural Refinement, and Distribution of Ti Sites in Titanium Silicalite-1 From ^47/49Ti NMR Crystallography at 28.2 Tesla. [PDF]

Angew Chem Int Ed Engl
Kaul CJ, Koppe J, Lätsch L, Wörle M, Aghazada S, Holmes JB, Wartmann C, Zheng M, Berkessel A, De Baerdemaeker T, Parvulescu AN, Seidel K, Teles JH, Yakimov AV, Copéret C.   +14 more
europepmc   +1 more source

Graphical Fourier-coefficient analysis as a paper-based method for teaching structure factors. [PDF]

Acta Crystallogr E Crystallogr Commun
Weirich TE.
europepmc   +1 more source

Exploring fibers with X-ray eyes. [PDF]

IUCrJ
Giannini C.
europepmc   +1 more source