Results 121 to 130 of about 662,036 (283)

Crystallography in France, a selective instant view

open access: yes, 2022
Special ReportInternational audienceAcademic scientific research in France is based around 70 universities, each with numerous departments, sites and branches, as well as around major research organisations.
van Der Lee, Arie   +7 more
core   +2 more sources

Magnetic Water Cleaning of Estrogens via Tight yet Dynamic Binding to Nanoparticles

open access: yesAdvanced Science, EarlyView.
Micropollution is one of the big challenges humanity faces with estrogen hormones being emerging pollutants of concern. Here, a supramolecular design strategy is presented that generates a simple nano‐adsorbent material to magnetically remove low‐concentrated estrogens from water.
Lukas Müller   +25 more
wiley   +1 more source

Quasi-Periodic Crystals—The Long Road from Discovery to Acceptance

open access: yesRambam Maimonides Medical Journal, 2013
[Extract] Three surprising discoveries on the nature of matter and its properties were published in the mid-1980s. All these discoveries led to Nobel prizes. The first discovery was in 1985, when fullerenes were discovered by Robert F.
Daniel Schechtman
doaj   +1 more source

Origin of Enhanced Efficiency and Reduced Roll‐Off in Organic Light‐Emitting Diodes Based on Pt(II) Complexes

open access: yesAdvanced Science, EarlyView.
Controlled Pt–Pt fine structure in square‐planar Pt(II) complexes governs metal–metal‐to‐ligand charge‐transfer (MMLCT) state formation, exciton dynamics, and organic light‐emitting diode performance. Short Pt–Pt contacts in Pt(fppz)2 enable coherent metal–metal coupling, sub‐microsecond emission and an external quantum efficiency of 29%, whereas ...
Atul Shukla   +15 more
wiley   +1 more source

Cryo-Crystallography: Diffraction at Low Temperature and More

open access: yes, 2011
This chapter comments on the motivations and the methods of crystallographic studies at low temperature. Cry-crystallography is a brunch of Crystallography, a science that is too often confused with a technique.
MacChi, Piero   +3 more
core   +1 more source

AS‐TLC‐Based High‐Throughput Screening Integrated with CuAAC Optimization Strategy Facilitates the Rapid Discovery of YTHDC1 Inhibitor

open access: yesAdvanced Science, EarlyView.
We developed Affinity Selection Thin‐Layer Chromatography (AS‐TLC) as a method for high‐throughput screening (HTS) of compound mixtures. Furthermore, we integrated activity assays with AS‐TLC and identified a YTH domain‐containing protein 1 (YTHDC1) inhibitor. Building on this hit, we applied copper(I)‐catalyzed azide–alkyne cycloaddition (CuAAC) click
Mingchen Wang   +19 more
wiley   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

open access: yesAdvanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu   +27 more
wiley   +1 more source

Words of Crystallography in the Italian Legal Language: A Diachronic Analysis

open access: yes
The goal of this work is to account, in a diachronic perspective, for the linguistic contact between legal language and the world of crystallography as an example of sectorial scientific ...
Francesco Romano, Andrea Ienco
core  

Reversible, Chemically Gated FRET via Ligand‐Activated Acceptors

open access: yesAdvanced Science, EarlyView.
Fluorogen binding turns the compact FAST tag into a tunable FRET acceptor, with ligand chemistry programming spectral overlap and excited‐state lifetimes. Fluorescence‐lifetime imaging reads out energy transfer through the shortened donor lifetime, while simply adding or washing out the dye switches FRET on and off, reversibly mapping the supramodular ...
Nivedita Singh   +7 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

open access: yesAdvanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho   +6 more
wiley   +1 more source

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