Results 181 to 190 of about 601,348 (294)

Erratum: A simple protocol for determining the zone axis direction from selected-area electron diffraction spot patterns of cubic materials. Addendum. Comprehensive tables for pattern reindexing. [PDF]

J Appl Crystallogr
Weirich TE.
europepmc   +1 more source

Ninth General Assembly and International Congress of Crystallography [PDF]

, 1970
null International Union of Crystallography
core   +1 more source

Coordination‐Driven Direct C─H Metalation of N‐Heterocycles With a Superbasic Co(II) Amide Co(TMP)2

Angewandte Chemie, EarlyView.
By enabling regioselectivities that are inaccessible with conventional bases, this study introduces a Co(II) amide platform for the deprotonative C─H metalation of sensitive N‐heterocycles. Subsequent interception of the resulting Co(II) intermediates with external oxidants affords a family of sterically congested, TMP‐substituted heterocycles via C─N ...
Na Jin, Manting Mu, Max García‐Melchor, Eva Hevia   +3 more
wiley   +2 more sources

Macromolecular crystallography at Elettra: current and future perspectives. Corrigendum. [PDF]

J Synchrotron Radiat
Hegde RP, Demitri N, Héroux A, Olivo A, Bais G, Cianci M, Storici P, Dumitrescu DG, Varshney NK, Gopal B, Sarma DD, Vaccari L, Onesti S, Polentarutti M.   +13 more
europepmc   +1 more source

Enhancing Enzyme Activity With Mutation Combinations Guided by Few‐Shot Learning and Causal Inference

Angewandte Chemie, EarlyView.
We present an integrated workflow that predicts activity‐enhancing mutation combinations from minimal experimental data. By proposing in vivo unit yield (yield/expression) as a surrogate for kcat/Km through causal inference, and visualizing local activity landscape, it effectively guides product yield improvement. ABSTRACT Designing enzyme sequences to
Lin Guo, Xiaoguang Yan, Yali Lu, Shengxin Nie, Mingyue Ge, Yukun Li, Weiguo Li, Xiaochun Zhang, Dongmei Liang, Yihan Zhao, Hongxiao Tan, Xiling Chen, Shilong Fan, Yefeng Tang, Jianjun Qiao, Boxue Tian   +15 more
wiley   +2 more sources

Pinpointing Protein Crystal Structures over a Broad Temperature Range Using Hydrophobic Protection. [PDF]

ACS Omega
Ribeiro FS, Lima LMTR.
europepmc   +1 more source

Organocatalytic Enantioselective Addition of Malonates to Cyclic Imines: A Short Total Synthesis of Tetraponerine T‐1

Angewandte Chemie, EarlyView.
A stereoselective functionalization method of cyclic imines under mild organocatalytic conditions was developed. Bifunctional cinchona alkaloid catalysts combined with carefully optimized reaction conditions to suppress background reactivity enabled highly enantio‐ and diastereoselective addition reactions of malonates to cyclic imines.
Frederic Kölblin, Helma Wennemers
wiley   +2 more sources

Generation and modulation of catalytically relevant states of a dye-decolourizing peroxidase using time-resolved serial femtosecond crystallography with drop-on-chip mixing and X-ray-driven reduction. [PDF]

Acta Crystallogr D Struct Biol
Lučić M, Glerup J, Aller P, Axford D, Devenish N, Park J, Shilova A, Landeros de la Isla A, Strange RW, Zhou T, Owen RL, Worrall JAR, Hough MA.   +12 more
europepmc   +1 more source

A Multi‐Stimuli Transformational Network of Benzil‐Based Pd(II) Assemblies

Angewandte Chemie, EarlyView.
Incorporation of a flexible and chemically reactive benzil backbone into the ligand structure allows it to access multiple conformations, enabling the formation of diverse homo‐ and heteroleptic Pd(II) assemblies with different nuclearities and topologies.
Zhiwei Zeng, A. Priscila Gia, Alexander S. Mikherdov, Mert Acar, Björn Schmidt, Guido H. Clever   +5 more
wiley   +2 more sources

Visualizing and teaching crystallographic symmetry using Jmol. [PDF]

Acta Crystallogr C Struct Chem
Johnston DH, Hanson RM.
europepmc   +1 more source