Mutation of active site glutamate in serine hydroxymethyltransferase allows trapping a reactive intermediate: a combined neutron and X-ray crystallography study. [PDF]
Drago VN, Phillips RS, Kovalevsky A.
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Quantum‐Level Influences on Enzyme Reactions and Their Ripple Effects on Biological Phenomena
Because living organisms are ultimately composed of atoms and molecules, quantum‐mechanical effects are expected to contribute to biological phenomena. Quantum biology seeks to elucidate life processes from a quantum‐mechanical perspective. This review discusses how quantum‐level effects, including quantum tunneling, may propagate from enzymatic proton‐
Takeshi Yasuda
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Structural insights into urocanate reductase using room-temperature X-ray crystallography. [PDF]
Aggarwal S +4 more
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Abstract Cross‐disciplinary research is a priority for many academic institutions, with a growing body of scholarship dedicated to studying the central practice of cross‐disciplinarity: integration, or the synthesis of knowledge, information, and data across disciplines and domains.
Ciara Zogheib
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Speciation, Structural Refinement, and Distribution of Ti Sites in Titanium Silicalite-1 From <sup>47/49</sup>Ti NMR Crystallography at 28.2 Tesla. [PDF]
Kaul CJ +14 more
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ABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Farhat Ansari, Tarushi, Vandan Nagar
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Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1. [PDF]
Doppler D +38 more
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Pectinase‐Based Bioprocesses for Circular Bioeconomy and Sustainable Industrial Development
This picture demonstrates a unified strategy for sustainable pectinase production, focusing on microbial bioproduction, innovative strategies in enzyme engineering (Protein engineering, rational enzyme design, directed evolution and heterologous expression) and various applications in industry, including food, textiles, pulp and paper, agriculture and ...
Nisha Sharma +6 more
wiley +1 more source
AXIS: a Lab-in-the-Loop machine learning approach for automated detection of macromolecular crystals. [PDF]
Personnaz A +9 more
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