Results 51 to 60 of about 745,236 (302)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Granular Crystals: Controlling Mechanical Energy with Nonlinearity and Discreteness [PDF]
, 2011 The presence of structural discreteness and periodicity can affect the propagation of phonons, sound, and other mechanical waves. A fundamental property of many of the periodic structures and materials designed for this purpose is the presence of ...
Boechler, Nicholas Sebastian
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
, 2020 Liquid crystals were discovered by Friedrich Reinitzer in 1888 when he observed colors in cholesterol derivatives that are characteristic of highly birefringent materials [...
Charles Rosenblatt
core +1 more source
Large Angle Forward Diffraction by Chiral Liquid Crystal Gratings with Inclined Helical Axis
Crystals, 2020 A layer of chiral liquid crystal (CLC) with a photonic bandgap in the visible range has excellent reflective properties. Recently, two director configurations have been proposed in the literature for CLC between two substrates with periodic photo ...
Migle Stebryte +4 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Crystal structures and Hirshfeld analysis of 4,6-dibromoindolenine and its quaternized salt
Acta Crystallographica Section E: Crystallographic Communications, 2021 4,6-Dibromo-2,3,3-trimethyl-3H-indole, C11H11Br2N, exists as a neutral molecule in the asymmetric unit. The asymmetric unit of 4,6-dibromo-2,3,3-trimethyl-3H-indol-1-ium iodide, C12H14Br2N+·I−, contains one organic cation and one iodine anion.
Irina S. Konovalova +4 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Crystal engineering studies: polymorphs and co-crystals [PDF]
, 2012 Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166We review the key topics of one of the areas with the biggest impact of the last years in the chemical and pharmaceutical industry that is Crystal Engineering.
Puigjaner Vallet, Ma. Cristina +1 more
core +5 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source