Results 61 to 70 of about 745,236 (302)

Fabrication of Sio2-based microcantilevers by anisotropic chemical etching of (100) single crystal Si [PDF]

open access: yesJournal of the Serbian Chemical Society, 2007
The undercutting process of thermal SiO2 microcantilevers with different orientations on (100) Si wafer was studied. The silicon substrate was removed by anisotropic chemical etching with a 25 wt. % aqueous solution of TMAH or a 30 wt.
Jović Vesna   +3 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Molecular Shape Related Effects in Liquid Crystals

open access: yes, 2015
Liquid crystals are organic materials constituting of molecules characterized by strong shape anisotropy. Many studies unambiguously showed that some important physical effects observed in liquid crystals are strongly dependent on the shape anisotropy of
Komitov, Lachezar,
core   +1 more source

Plasticity size effects in tension and compression of single crystals [PDF]

open access: yes, 2005
The effect of size and loading conditions on the tension and compression stress–strain response of micron-sized planar crystals is investigated using discrete dislocation plasticity.
Deshpande, V.S.,   +6 more
core   +2 more sources

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Molecular Packing Interaction in DNA Crystals

open access: yes, 2020
DNA crystallography provides essential structural information to understand the biochemical and biological functions of oligonucleotides. Therefore, it is necessary to understand the factors affecting crystallization of DNA to develop a strategy for ...
Vinod Kumar Subramani   +3 more
core   +1 more source

Liquid Crystals Templating [PDF]

open access: yes, 2020
Liquid crystal templating is a versatile technique to create novel organic and inorganic materials with nanoscale features. It exploits the self-assembled architectures of liquid crystal phases as scaffolds.
Mamatha Nagaraj, Nagaraj, M
core   +1 more source

Effect of starting materials and sintering temperature on microstructure and optical properties of Y2O3:Yb3+ 5 at% transparent ceramics

open access: yesJournal of Advanced Ceramics, 2020
Y2O3:Yb3+ 5 at% ceramics have been synthesized by the reactive sintering method using different commercial yttria powders (Alfa-Micro, Alfa-Nano, and ITO-V) as raw materials.
R. P. Yavetskiy   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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