Results 61 to 70 of about 368,627 (268)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Laser ablation and photostimulated passivation of the surface of Cd1–хZnхTe crystals

Технологія та конструювання в електронній апаратурі, 2011
A new physical method of Cd1–хZnхTe-detectors passivation is proposed — the treatment of crystal surface by a laser ablation (LA) with subsequent photostimulated passivation (PhSP), during wich a high-resistance oxide layer is formed on it’s surface ...
Yu. A. Zagoruiko, N. O. Kovalenko, V. A. Khristyan, O. A. Fedorenko, A. S. Gerasimenko, M. V. Dobrotvorskaya, P. V. Mateychenko   +6 more
doaj  

Water of Crystallization [PDF]

Science, 1884
n ...
openaire   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Thermostable interference oxide coatings for active elements of IR lasers

Технологія та конструювання в електронній апаратурі, 2010
Strong thermostable oxide interference coatings transparent in the visible and IR spectral regions are obtained on the surface of active elements of ZnSe:Cr2+-lasers by the method of photothermal oxidation.
Yu. A. Zagoruiko, O. A. Fedorenko, N. O. Kovalenko, E. A. Kuzminov, N. O. Kovalenko, P. V. Mateychenko   +5 more
doaj  

Research of the Single Crystal and Multilayer Composite Detectors Response Under Irradiation by Fast Neutrons

East European Journal of Physics, 2019
The object of this work was to study the response of the detectors based on the oxide scintillators under irradiation by a flux of fast neutrons from 239Pu-Be source by counting photomultiplier tube pulses.
Volodymyr Ryzhikov, Gennadiy Onyshchenko, Ivan Yakymenko, Sergei Naydenov, Alexandr Opolonin, Sergei Makhota   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Rice Physiology, Products, and Critical Steps Associated with Postharvest Operations in Southern Florida

EDIS, 2019
This 5-page document pertains to the UF/IFAS Extension programs related to rice production in the EAA and focuses on the steps that comprise postharvest processing of rice (drying, tempering, milling, and storage). It aims to highlight the physiology of
Jehangir H Bhadha, Sangeeta Mukhopadhyay, Charlene Andrews, Matthew VanWeelden   +3 more
doaj  

Impact of starting alumina powders on densification peculiarities of reactive-sintered YAG:Sm3+ ceramics

Open Ceramics
YAG:Sm3+ (5 at.%) transparent ceramics have been obtained by reactive sintering using different starting Al2O3 powders. Effect of particle size in the 100–400 nm range, morphology and dispersity of starting alumina powders on the properties of YAG:Sm3 ...
O․O․ Matvienko, I․O․ Vorona, S․V․ Parkhomenko, A․E․ Balabanov, А․Т․ Budnikov, A․D․ Tymoshenko, P․V․ Mateychenko, А․V․ Tolmachev, V․N Baumer, G․V․ Grygorova, Ya. Korol, R․P․ Yavetskiy   +11 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source