Results 81 to 90 of about 745,236 (302)

Research of the Single Crystal and Multilayer Composite Detectors Response Under Irradiation by Fast Neutrons

open access: yesEast European Journal of Physics, 2019
The object of this work was to study the response of the detectors based on the oxide scintillators under irradiation by a flux of fast neutrons from 239Pu-Be source by counting photomultiplier tube pulses.
Volodymyr Ryzhikov   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Multiplexed holographic transmission gratings recorded in holographic polymer-dispersed liquid crystals: static and dynamic studies [PDF]

open access: yes, 2005
The optimization of the experimental parameters of two multiplexed holographic transmission gratings recorded in holographic polymer-dispersed liquid crystals is investigated.
Camacho, Maria   +4 more
core   +1 more source

Thermostable interference oxide coatings for active elements of IR lasers

open access: yesТехнологія та конструювання в електронній апаратурі, 2010
Strong thermostable oxide interference coatings transparent in the visible and IR spectral regions are obtained on the surface of active elements of ZnSe:Cr2+-lasers by the method of photothermal oxidation.
Yu. A. Zagoruiko   +5 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Rice Physiology, Products, and Critical Steps Associated with Postharvest Operations in Southern Florida

open access: yesEDIS, 2019
This 5-page document pertains to the UF/IFAS Extension programs related to rice production in the EAA and focuses on the steps that comprise postharvest processing of rice (drying, tempering, milling, and storage). It aims to highlight the physiology of
Jehangir H Bhadha   +3 more
doaj  

The Investigation of Mechanisms of Fast Neutron Registration in Oxide Scintillators

open access: yesEast European Journal of Physics, 2019
The contributions of gamma rays from the inelastic scattering reaction and the resonant reaction in the process of slowing down fast neutrons inside the oxide detector volume are investigated.
Gennadiy Onyshchenko   +6 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The technology of microcircuit assembly on flexible polyimide substrate

open access: yesТехнологія та конструювання в електронній апаратурі, 2010
The research is devoted to technology of microcircuit assembly on flexible polyimide substrate. It is proved that such microcircuits provide high reliability and have advantage over other IC models when applied in hermetic micro-assemblies in ...
Н. И. Плис   +5 more
doaj  

Home - About - Disclaimer - Privacy