Results 71 to 80 of about 368,627 (268)
Chemical shifts and spin–lattice relaxation times are measured using 1H MAS NMR, 13C CP/MAS NMR, and 14N MAS NMR techniques to understand the structural geometry and dynamics of the alkyl and ammonium groups in layered perovskite (CH3CH2CH2NH3)2CuCl4 ...
Seong Eun Jang, Mi Jung Kim, Ae Ran Lim
doaj +1 more source
The Investigation of Mechanisms of Fast Neutron Registration in Oxide Scintillators
The contributions of gamma rays from the inelastic scattering reaction and the resonant reaction in the process of slowing down fast neutrons inside the oxide detector volume are investigated.
Gennadiy Onyshchenko +6 more
doaj +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
The technology of microcircuit assembly on flexible polyimide substrate
The research is devoted to technology of microcircuit assembly on flexible polyimide substrate. It is proved that such microcircuits provide high reliability and have advantage over other IC models when applied in hermetic micro-assemblies in ...
Н. И. Плис +5 more
doaj
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
LABORATORY EQUIPMENT DURING PHARMACEUTICAL DEVELOPMENT OF SEMI-SOLID PREPARATIONS
Introduction. When developing drugs it is necessary to use laboratory equipment that simulates pilot and industrial equipment. For the production of semi-solid preparations the key equipment are rotor-stator dispersers and vacuum reactors-homogenizers ...
N. A. Lyapunov +5 more
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Radiation-resistant plastic scintillators [PDF]
Fluorinederivatives of 4'-phenyl-3-hydroxyflavone have been synthesized and used as activators for radiation-resistant plastic scintillators based on polystyrene. Plastic scintillators containing 1.0 wt.
D. A. Yelisieiev +5 more
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source

