Results 61 to 70 of about 127,372 (294)

Conformation‐Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems

open access: yesAngewandte Chemie, EarlyView.
Intramolecular chemically induced dimerisation transforms FK506‐ and cyclosporine A‐responsive protein pairs into high‐affinity pseudo‐allosteric switches. Holo‐selective binders isolated by mRNA display convert these switches into gain‐of‐signal biosensors and ultrasensitive ELISAs, enabling direct quantification of both immunosuppressants in ...
Zhenling Cui   +15 more
wiley   +2 more sources

Description of the calculations used to determine the overall Consequence Spatial Analysis (CSA) risk score for each scoring element in the MSC CSA and the CSA carbon extension.

open access: yes, 2023
Description of the calculations used to determine the overall Consequence Spatial Analysis (CSA) risk score for each scoring element in the MSC CSA and the CSA carbon extension.
Graham Epstein (4011584)   +4 more
core   +1 more source

Dual‐Dynamically Crosslinked Nanogels Enable Prolonged Ocular Retention for Multimodal Dry Eye Therapy

open access: yesAdvanced Science, EarlyView.
This berberine‐loaded dual‐dynamically crosslinked nanogel integrates tannic acid‐zinc metal‐phenolic networks and carboxymethyl chitosan/aldehyde‐functionalized poly(ethylene glycol) dynamic Schiff base networks, achieving 1‐year colloidal and antioxidant stability, sustained corneal berberine exposure for 24 h to support convenient once‐daily dosing,
Yanru Xin   +7 more
wiley   +1 more source

CORPORATE PERFORMANCE MEASUREMENT: AN INTEGRATED APPROACH [PDF]

open access: yesAnnals of the University of Oradea: Economic Science, 2017
The online retail market has achieved dynamic growth in recent years, making up 4% of the total retail sales. Not only the net sales in e-commerce have grown, but also its share of the whole trade has increased gradually.
Csáki-Darabos Rita
doaj  

Comparison of C-CSA and NC-CSA among different age groups in DMD and control groups.

open access: yes, 2015
Red and blue color represents N-CSA and C-CSA respectively. Symbol colors are accordant with the bar colors (red; N-CSA, blue; C-CSA).
Krista Vandenborne (300724)   +10 more
core   +1 more source

NUB1 Regulates Muscle Atrophy in Lung Cancer Cachexia via NF‐κB Signaling Pathway

open access: yesAdvanced Science, EarlyView.
ABSTRACT Cancer‐associated cachexia (CAC) is a devastating multifactorial syndrome characterized by progressive skeletal muscle atrophy. Its mechanisms remain incompletely clarified, with limited effective therapeutic targets. NUB1, a negative regulator of ubiquitin‐like proteins mediating protein degradation, has not been fully elucidated in CAC ...
Yuqi Han   +13 more
wiley   +1 more source

Associations for Citizen Science: Regional Knowledge, Global Collaboration

open access: yesCitizen Science: Theory and Practice, 2016
Since 2012, three organizations advancing the work of citizen science practitioners have arisen in different regions: The primarily US-based but globally open Citizen Science Association (CSA), the European Citizen Science Association (ECSA), and the ...
Martin Storksdieck   +9 more
doaj   +1 more source

Western blot analysis of CSA and CSB.

open access: yes, 2018
Exosporial extracts probed with anti-CsA (A), anti-CsB (B) and anti-whole spore antibodies (C) and recombinant CsB probed with anti-whole spore antibodies (D).
Rebecca Rabi (5117834)   +5 more
core   +1 more source

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu   +12 more
wiley   +1 more source

Different-Wavelength Lasers In Root Canal Disinfection

open access: yesInternational Dental Journal
Aim or purpose: To compare the antibacterial efficacy of ultrasonic activation (UA), Er,Cr:YSGG laser, Er:YAG laser, and thulium fiber laser (TFL) in root canal treatment.
Lu Tang, Ying Zhao, Yuhao Bai
doaj   +1 more source

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