Blood stem cell collections after mobilization with combination chemotherapy containing ifosfamide followed by G-CSF in multiple myeloma [PDF]
High-dose chemotherapy with autologous peripheral blood stem cell transplantation is the standard treatment of patients with multiple myeloma today. In this study we used a combination mobilizing chemotherapy containing ifosfamide with G-CSF before stem ...
Werding, N. +5 more
core +2 more sources
G-CSF or not G-CSF? That is the question [PDF]
Although administration of myeloid colony-stimulating factors (G-CSF or GM-CSF) has been routinely used to increase the rate of neutrophil recovery, evidence suggests that clinical efficacy in the transplant setting is doubtful (Table 1). We performed two consecutive prospective randomized trials to assess the use of G-CSF (filgrastim) after autologous
M A Canales, F Hernández-Navarro
openaire +1 more source
The embryonic blood-CSF barrier has molecular elements for specific glucose transport and for the general transport of molecules via transcellular routes. [PDF]
In vertebrates, early brain development takes place at the expanded anterior end of the neural tube, which is filled with embryonic cerebrospinal fluid (E-CSF).
Bueno i Torrens, David, 1965- +3 more
core +1 more source
Diagnostic approach to autoimmune encephalitis (ORP-15) [PDF]
Autoimmune encephalitis is the commonest form of non_infectious encephalitis. It occurs secondary to three groups autoantibodies targeting neural epitopes like: neuronal cell surface proteins (e.g., as NMDAR, LGI1, and CASPR2, GABABR and AMPAR, Synaptic ...
Hoda Kamali
doaj
CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias [PDF]
The diagnosis of Creutzfeldt- Jakob disease (CJD) is still made by exclusion of other dementias. We now evaluated lactate dehydrogenase (LDH) in the cerebrospinal fluid (CSF) as a possible additional diagnostic tool. CSF LDH levels of patients with CJD (
Cepek, L. +9 more
core +1 more source
Tiananmen Protests and Lessons for Democratization in Vietnam [PDF]
Tiananmen Protests is a shorthand for a seven-week long, nation-wide social movement that spread throughout mainland China in 1989. Looking back at the Tiananmen Protests after 30 years we can learn some lessons to emulate or to avoid in any ...
Nguyen Quang A
doaj
Background: Different antiretroviral therapies (ARTs) may have differing effects on central nervous system (CNS) function. We assessed CNS pharmacodynamic effects of switching integrase inhibitors in people-with-HIV (PWH).
Borja Mora-Peris +10 more
doaj +1 more source
Baclofen is a racemic mixture that is commonly used for the treatment for spasticity. However, the optimal dose and dosing interval to achieve effective cerebral spinal fluid (CSF) concentrations of baclofen are not known.
Qingfeng He +3 more
doaj +1 more source
CSF concentrations of cAMP and cGMP are lower in patients with Creutzfeldt-Jakob disease but not Parkinson's disease and amyotrophic lateral sclerosis. [PDF]
The cyclic nucleotides cyclic adenosine-3',5'-monophosphate (cAMP) and cyclic guanosine-3',5'-monophosphate (cGMP) are important second messengers and are potential biomarkers for Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and ...
Oeckl, Patrick +23 more
core +1 more source
G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial [PDF]
Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
Tobias Warnecke +32 more
core +1 more source

