Results 41 to 50 of about 483,708 (307)

G-CSF Prevents the Progression of Structural Disintegration of White Matter Tracts in Amyotrophic Lateral Sclerosis: A Pilot Trial

, 2011
Background: The hematopoietic protein Granulocyte-colony stimulating factor (G-CSF) has neuroprotective and regenerative properties. The G-CSF receptor is expressed by motoneurons, and G-CSF protects cultured motoneuronal cells from apoptosis.
Tobias Warnecke, Schneider, A, Deppe Michael, Floel, A, Thomas Duning, Harald Kugel, Mohammadi Siawoosh, Katja Kolpatzik, Knecht Stefan, Schiffbauer, H, Wolf Rüdiger Schäbitz, Hagen Schiffbauer, Schäbitz Wolf Rüdiger, Duning Thomas, Kugel Harald, Knecht, S, Warnecke Tobias, Agnes Floel, Kolpatzik, K, Warnecke, T, Floel Agnes, Kugel, H, Schabitz, WR, Deppe, M, Kolpatzik Katja, Armin Schneider, Mohammadi, S, Michael Deppe, Duning, T, Schneider Armin, Stefan Knecht, Siawoosh Mohammadi, Schiffbauer Hagen   +32 more
core   +1 more source

Navigating herpes simplex encephalitis: Family medicine perspectives from Jharkhand, India

Journal of Family Medicine and Primary Care
Background: Herpes simplex encephalitis (HSE), caused by herpes simplex virus (HSV) is the most common cause of sporadic encephalitis that often presents as an emergency case of acute or sub-acute nature associated with poor prognosis.
Amit Kumar Patel, Ashok Kumar Sharma, Kumari Seema, Abhay Kumar, Manju Boipai, Rishi Tuhin Guria, Upendra Prasad Sahu, Manoj Kumar   +7 more
doaj   +1 more source

Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity [PDF]

Journal of Medical Biochemistry, 2009
Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity.
Vezmar Sandra, Bode Udo, Jaehde Ulrich
doaj  

Human parechovirus meningoencephalitis

South African Journal of Radiology, 2023
Human parechovirus-3 (HPeV-3) infection is one of the differential diagnoses of neonatal meningoencephalitis. A 13-day-old full-term female neonate presented with a seizure.
Pokhraj P. Suthar, Kathryn Hughes, Geetanjalee Kadam, Miral Jhaveri, Santhosh Gaddikeri   +4 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Sensory Acceptability of Dual-Fortified Milled Red and Yellow Lentil (Lens culinaris Medik.) Dal in Bangladesh

Foods, 2020
This study evaluated the sensory properties of uncooked and cooked milled lentils that were fortified with varying concentrations of Fe and Zn in the form of NaFeEDTA and ZnSO4.H2O, respectively.
Rajib Podder, Mahmudul Hassan Al Imam, Israt Jahan, Fakir Md Yunus, Mohammad Muhit, Albert Vandenberg   +5 more
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Enterovirus Detection in Patients Suspected Aseptic Meningitis by RT-PCR in Kermanshah, Iran [PDF]

Journal of Kerman University of Medical Sciences, 2018
Background: Aseptic meningitis is frequently caused by viral agents, particularly human enterovirus. Several methods of Reverse Transcription PCR(RT-PCR) have recently been introduced and modified for better diagnosis of enteroviral infection in ...
Alisha Akya, Azam Elahi, Mohsen Moghoofei, Roya Chegenelorestani, Ahmad Nejati, Farhad Babaei   +5 more
doaj  

Differentiation of Leptomeningeal and Vascular Enhancement on Post-contrast FLAIR MRI Sequence: Role in Early Detection of Infectious Meningitis [PDF]

Journal of Clinical and Diagnostic Research, 2015
Objective: To qualitatively and quantitatively differentiate leptomeningeal and vascular enhancement on Post-contrast Fluid Attenuated Inversion Recovery (PCFLAIR) sequence compared to post-contrast T1-weighted (PCT1W) sequence with fat suppression ...
Armeen Ahmad, Sheenam Azad, Rajiv Azad
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source