Results 61 to 70 of about 521,531 (302)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Critical Success factors for implementing PACS Technology in Iran\'s Hospitals

International Journal of Information and Communication Technology Research, 2017
This study clarified the critical success factors (CSFs) that effect on adopting and implementing PACS and its applications in Iranian hospitals. We identified CSFs by literature review and interview by experts.
Fatemeh Saghafi, Zainabolhoda Heshmati, Mahmood Heydari, Mohammad Khansari   +3 more
doaj  

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Pomalidomide counters GM-CSF-triggered CD14 and TLR downregulation and partly reverts the GM-CSF-induced effects on cytokine production.

, 2016
(a-d) Treatment with pomalidomide alone did not change monocyte TLR and CD 14 but revert the GM-CSF-induced downregulation of TLR1 (a), TLR2 (b), TLR4 (c) and CD14 (d).
Lukas Wisgrill (624486), Isabelle Wessely (3190410), Simone Schüller (3190404), Celia Dürr (3190401), Arnold Pollak (331546), Kambis Sadeghi (3190407), Andreas Spittler (117544), Elisabeth Förster-Waldl (359199), Armando Heinle (3190413), Susanne C. Diesner (359191), Monika Sachet (262810)   +10 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Navigating herpes simplex encephalitis: Family medicine perspectives from Jharkhand, India

Journal of Family Medicine and Primary Care
Background: Herpes simplex encephalitis (HSE), caused by herpes simplex virus (HSV) is the most common cause of sporadic encephalitis that often presents as an emergency case of acute or sub-acute nature associated with poor prognosis.
Amit Kumar Patel, Ashok Kumar Sharma, Kumari Seema, Abhay Kumar, Manju Boipai, Rishi Tuhin Guria, Upendra Prasad Sahu, Manoj Kumar   +7 more
doaj   +1 more source

A Prospective Observational Study of Children with FS-Associated Hospitalization: The Implication and Outcomes of Pathogen Detection in Cerebrospinal Fluid

International Journal of General Medicine, 2023
Fang Chen,* Fan Feng,* Dianping You, Yinghui Guo, Shuo Yang, Tong Zhao, Suzhen Sun,* Le Wang* Institute of Pediatric Research, Children’s Hospital of Hebei Province, Shijiazhuang, 050031, People’s Republic of China*These authors ...
Chen F, Feng F, You D, Guo Y, Yang S, Zhao T, Sun S, Wang L   +7 more
doaj  

Recognition of handwritten digits by features and a multi-layer perceptron

, 1992
International audienceHandwritten digit recognition was one of the first areas in which neural network technology was applied. Thomson-CSF/LER has developed an intermediate approach between classical methods, based on extracting small sets of parameters,
Pottier, Isabelle, Burel, Gilles
core  

Pathophysiology of Skull Base Defect and CSF Leak

, 2022
Cerebrospinal fluid rhinorrhea is the result of a pathologic communication between the subarachnoid space and the nasal cavity. This condition most often occurs secondary to an inciting event, but it can also develop unexpectedly. The epidemiology of CSF
Reilly, Erin, Casiano, Roy
core   +1 more source