Results 61 to 70 of about 734,560 (306)

Enterovirus Detection in Patients Suspected Aseptic Meningitis by RT-PCR in Kermanshah, Iran [PDF]

Journal of Kerman University of Medical Sciences, 2018
Background: Aseptic meningitis is frequently caused by viral agents, particularly human enterovirus. Several methods of Reverse Transcription PCR(RT-PCR) have recently been introduced and modified for better diagnosis of enteroviral infection in ...
Alisha Akya, Azam Elahi, Mohsen Moghoofei, Roya Chegenelorestani, Ahmad Nejati, Farhad Babaei   +5 more
doaj  

Microbial Etiology of Community-Acquired Meningo-encephalitis In Adults: A Retrospective Review

Journal of Microbiology and Infectious Diseases, 2021
Objectives: Meningoencephalitis (ME) is a well-recognized clinical entity with diverse infectious etiologies. Only a few studies in the Indian literature are available on this issue, especially in the adult population.
Rohit Vashisht, Ram Gopalakrishnan, Senthur Nambi, Dorairajan Sureshkumar, Nandini Sethuraman, Yamunadevi Ramanathan, Ramasubramanian V   +6 more
doaj   +1 more source

BAFF Index and CXCL13 levels in the cerebrospinal fluid associate respectively with intrathecal IgG synthesis and cortical atrophy in multiple sclerosis at clinical onset [PDF]

, 2017
Background B lymphocytes are thought to play a relevant role in multiple sclerosis (MS) pathology. The in vivo analysis of intrathecally produced B cell-related cytokines may help to clarify the mechanisms of B cell recruitment and ...
Ermani, M., Federle, L., Gallo, P., Miante, S., Perini, P., Poggiali, D., Pravato, S., Puthenparampil, M., Rinaldi, F., Ruggero, S., Toffanin, E., Zito, Alberto   +11 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Optimum imaging and diagnosis of cerebrospinal fluid rhinorrhoea [PDF]

, 2000
Imaging is an important component in the investigation of unilateral watery rhinorrhoea suspicious of cerebrospinal fluid (CSF). Whilst the demonstration of the presence of beta 2 transferrin confirms that CSF is present it may prove difficult to ...
Howard, D, Lloyd, G, Lund, VJ, Savy, L
core   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela, Madison Reeves, Karen Jansen‐West, Judith Dunmore, Yuping Song, Audrey Strongosky, Sunil Gandhi, Gilana Pikover, Matt Blurton‐Jones, Robert C. Spitale, Erik H. Middlebrooks, Leonard Petrucelli, Mercedes Prudencio, Zbigniew K. Wszolek   +13 more
wiley   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Partial Validation of Ultra Performance Liquid Chromatography Method for Quantification of Isoniazid-Pyrazinamide in Human Samples [PDF]

Journal of Pure and Applied Chemistry Research, 2021
Isoniazid (INH) and pyrazinamide (PZA) are first-line drugs in the treatment of meningitis of tuberculosis, in addition to rifampicin. The use of these drugs will determine the success of therapy to kill Mycobacterium tuberculosis in brain tissue that is
Vycke Yunivita, Triana Nurul Meirina, Atu Purnama Dewi, Harold Eka Atmaja, Rovina Ruslami   +4 more
doaj  

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Implementation of Computerized Physician Order Entry (CPOE) towards Patient Safety in Saudi Hospitals

Journal of High Institute of Public Health, 2008
In the last 10 to 15 years, the healthcare industry has clearly shifted its focus from implementing financial information systems to clinical information systems in order to improve outcomes, reduce medication errors, increase healthcare efficiency, and ...
Majid M. Altuwaijri
doaj   +1 more source