Results 51 to 60 of about 734,560 (306)

Human parechovirus meningoencephalitis

South African Journal of Radiology, 2023
Human parechovirus-3 (HPeV-3) infection is one of the differential diagnoses of neonatal meningoencephalitis. A 13-day-old full-term female neonate presented with a seizure.
Pokhraj P. Suthar, Kathryn Hughes, Geetanjalee Kadam, Miral Jhaveri, Santhosh Gaddikeri   +4 more
doaj   +1 more source

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders. [PDF]

, 2019
Purpose of reviewThe aim of this study was to examine the synaptic biomarker neurogranin in cerebrospinal fluid (CSF) in different stages of HIV infection and in relation to what is known about CSF neurogranin in other neurodegenerative diseases.Recent ...
Blennow, Kaj, Fuchs, Dietmar, Gisslén, Magnus, Price, Richard W, Spudich, Serena, Yilmaz, Aylin, Zetterberg, Henrik   +6 more
core   +2 more sources

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Navigating herpes simplex encephalitis: Family medicine perspectives from Jharkhand, India

Journal of Family Medicine and Primary Care
Background: Herpes simplex encephalitis (HSE), caused by herpes simplex virus (HSV) is the most common cause of sporadic encephalitis that often presents as an emergency case of acute or sub-acute nature associated with poor prognosis.
Amit Kumar Patel, Ashok Kumar Sharma, Kumari Seema, Abhay Kumar, Manju Boipai, Rishi Tuhin Guria, Upendra Prasad Sahu, Manoj Kumar   +7 more
doaj   +1 more source

Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity [PDF]

Journal of Medical Biochemistry, 2009
Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity.
Vezmar Sandra, Bode Udo, Jaehde Ulrich
doaj  

Positive allosteric modulation as a potential therapeutic strategy in anti-NMDA receptor encephalitis [PDF]

, 2018
N-methyl-d-aspartate receptors (NMDARs) are ionotropic glutamate receptors important for synaptic plasticity, memory, and neuropsychiatric health. NMDAR hypofunction contributes to multiple disorders, including anti-NMDAR encephalitis (NMDARE), an ...
Benz, Ann, Brunwasser, Samuel J, Day, Gregory S, Doherty, James, Lewis, Michael, Mennerick, Steven, Paul, Steven M, Piccio, Laura, Quirk, Michael, Shu, Hong-Jin, Warikoo, Natasha, Zorumski, Charles F   +11 more
core   +2 more sources

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Differentiation of Leptomeningeal and Vascular Enhancement on Post-contrast FLAIR MRI Sequence: Role in Early Detection of Infectious Meningitis [PDF]

Journal of Clinical and Diagnostic Research, 2015
Objective: To qualitatively and quantitatively differentiate leptomeningeal and vascular enhancement on Post-contrast Fluid Attenuated Inversion Recovery (PCFLAIR) sequence compared to post-contrast T1-weighted (PCT1W) sequence with fat suppression ...
Armeen Ahmad, Sheenam Azad, Rajiv Azad
doaj   +1 more source

Key inflammatory pathway activations in the MCI stage of Alzheimer's disease [PDF]

, 2019
OBJECTIVE: To determine the key inflammatory pathways that are activated in the peripheral and CNS compartments at the mild cognitive impairment (MCI) stage of Alzheimer's disease (AD).
Bekris, Lynn M., Bena, James, Chance, Mark, Lamb, Bruce T., Leverenz, James B., Maxwell, Sean, Pillai, Jagan A., Rao, Stephen M.   +7 more
core   +2 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source