Results 41 to 50 of about 3,812 (175)

Anti-Classical Swine Fever Virus Strategies

Microorganisms, 2021
Classical swine fever (CSF), caused by CSF virus (CSFV), is a highly contagious swine disease with high morbidity and mortality, which has caused significant economic losses to the pig industry worldwide. Biosecurity measures and vaccination are the main
Jindai Fan, Yingxin Liao, Mengru Zhang, Chenchen Liu, Zhaoyao Li, Yuwan Li, Xiaowen Li, Keke Wu, Lin Yi, Hongxing Ding, Mingqiu Zhao, Shuangqi Fan, Jinding Chen   +12 more
doaj   +1 more source

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis

Oncotarget, 2017
Classical swine fever virus (CSFV), which causes typical clinical characteristics in piglets, including hemorrhagic syndrome and immunosuppression, is linked to hepatitis C and dengue virus. Oxidative stress and a reduced mitochondrial transmembrane potential are disturbed in CSFV-infected cells.
Gou, Hongchao, Zhao, Mingqiu, Xu, Hailuan, Yuan, Jin, He, Wencheng, Zhu, Mengjiao, Ding, Hongxing, Yi, Lin, Chen, Jinding   +8 more
openaire   +3 more sources

Classical Swine Fever Virus Infection Induces Endoplasmic Reticulum Stress-Mediated Autophagy to Sustain Viral Replication in vivo and in vitro

Frontiers in Microbiology, 2019
Endoplasmic reticulum (ER) stress-mediated autophagy plays significant roles in replication and pathogenesis of many animal viruses. However, the relationship between ER stress, autophagy, and viral replication during in vivo and in vitro infection of ...
Erpeng Zhu, Wenxian Chen, Yuwei Qin, Shengming Ma, Shuangqi Fan, Keke Wu, Wenhui Li, Jindai Fan, Lin Yi, Hongxing Ding, Jinding Chen, Mingqiu Zhao   +11 more
doaj   +1 more source

Pathogenicity and Genetic Characterization of Vietnamese Classical Swine Fever Virus: 2014–2018

Pathogens, 2020
Here, we examined the pathogenicity and genetic differences between classical swine fever viruses (CSFV) isolated on pig farms in North Vietnam from 2014−2018. Twenty CSFV strains from 16 pig farms were classified as genotype 2 (sub-genotypes 2.1b,
SeEun Choe, Van Phan Le, Jihye Shin, Jae-Hoon Kim, Ki-Sun Kim, Sok Song, Ra Mi Cha, Gyu-Nam Park, Thi Lan Nguyen, Bang-Hun Hyun, Bong-Kyun Park, Dong-Jun An   +11 more
doaj   +1 more source

Different RNA splicing mechanisms contribute to diverse infective outcome of classical swine fever viruses of differing virulence: insights from the deep sequencing data in swine umbilical vein endothelial cells [PDF]

PeerJ, 2016
Molecular mechanisms underlying RNA splicing regulation in response to viral infection are poorly understood. Classical swine fever (CSF), one of the most economically important and highly contagious swine diseases worldwide, is caused by classical swine
Pengbo Ning, Yulu Zhou, Wulong Liang, Yanming Zhang   +3 more
doaj   +2 more sources

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Genetic variation of classical swine fever virus based on palindromic nucleotide substitutions, a genetic marker in the 5' untranslated region of RNA [PDF]

Veterinaria Italiana, 2008
Forty-three strains of classical swine fever (hog cholera) virus (CSFV) from outbreaks in pigs in Europe, Asia and America, two strains from commercial CSFV modified live vaccines and a strain isolated from a diseased lamb from Spain were subjected to ...
Massimo Giangaspero, Ryô Harasawa
doaj  

Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever Virus and Border Disease Virus

Viruses, 2021
Classical swine fever virus (CSFV) shares high structural and antigenic homology with bovine viral diarrhea virus (BVDV) and border disease virus (BDV).
Yu-Liang Huang, Denise Meyer, Alexander Postel, Kuo-Jung Tsai, Hsin-Meng Liu, Chia-Huei Yang, Yu-Chun Huang, Nicholas Berkley, Ming-Chung Deng, Fun-In Wang, Paul Becher, Helen Crooke, Chia-Yi Chang   +12 more
doaj   +1 more source

Blood Biomarkers of Alzheimer's Disease and Patterns of Structural Brain Changes in the Community

Annals of Neurology, EarlyView.
Objective We aimed to investigate the associations between Alzheimer's disease (AD)‐related blood biomarkers and changes in brain volumes and cerebrovascular burden in community‐dwelling older adults. Methods We included 361 dementia‐free participants with a Mini‐Mental State Examination (MMSE) score ≥ 27 and without prior cerebrovascular events from a
Martina Valletta, Davide Liborio Vetrano, Erika J. Laukka, Grégoria Kalpouzos, Javier Oltra, Debora Rizzuto, Marco Canevelli, Claudia Fredolini, Chengxuan Qiu, Bengt Winblad, Laura Fratiglioni, Giulia Grande   +11 more
wiley   +1 more source

Porcine Viperin protein inhibits the replication of classical swine fever virus (CSFV) in vitro

Virology Journal, 2017
Background Classical swine fever virus (CSFV) is the causative pathogen of Classical swine fever (CSF), a highly contagious disease of swine. Viperin is one of the hundreds of interferon-stimulated genes (ISGs), and possesses a wide range of antiviral ...
Wenliang Li, Li Mao, Yongguo Cao, Bin Zhou, Leilei Yang, Linxiao Han, Fei Hao, Tao Lin, Wenwen Zhang, Jieyuan Jiang   +9 more
doaj   +1 more source