Results 41 to 50 of about 6,850 (217)

Classical swine fever virus (CSFV) envelope glycoprotein E2 containing one structural antigenic unit protects pigs from lethal CSFV challenge

Journal of General Virology, 1996
Envelope glycoprotein E2, formerly called E1 or gp51-54, of classical swine fever virus (CSFV) expressed in insect cells protects swine from classical swine fever. Monoclonal antibodies directed against epitopes of domains B and C and subdomain A1 are neutralizing.
van Rijn, P.A., Bossers, A., Wensvoort, G., Moormann, R.J.M.   +3 more
openaire   +3 more sources

Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus

Viruses, 2019
Vaccines against classical swine fever have proven very effective in protecting pigs from this deadly disease. However, little is known about how vaccination impacts the selective pressures acting on the classical swine fever virus (CSFV).
Ulrik Fahnøe, Anders Gorm Pedersen, Camille Melissa Johnston, Richard J. Orton, Dirk Höper, Martin Beer, Jens Bukh, Graham J. Belsham, Thomas Bruun Rasmussen   +8 more
doaj   +1 more source

AIF1 was identified as an up-regulated gene contributing to CSFV Shimen infection in porcine alveolar macrophage 3D4/21 cells [PDF]

PeerJ, 2020
Classical swine fever (CSF) is a disease that is characterized by diffuse hemorrhaging, high fever, and high mortality rates. The pro-inflammatory characteristics of allograft inflammatory factor 1 (AIF1) have been well documented; however, insufficient ...
Xiaocheng Gong, Xuepeng Li, Xin You, Aoxue Hu, Min Liu, Huimin Yao, Jun He, Xianghan Zhang, Pengbo Ning   +8 more
doaj   +2 more sources

CO-INFECTIONS OF CLASSICAL SWINE FEVER VIRUS, PORCINE SAPELOVIRUS AND PORCINE CIRCOVIRUS 2 IN DIARRHEIC PIGLETS: EVIDENCE FROM KARNATAKA, INDIA [PDF]

Exploratory Animal and Medical Research
Suckling and weaned piglets suffering from gastrointestinal disorders often develop diarrhea due to viral co-infections. Classical swine fever virus, porcine sapelovirus, and porcine circovirus type 2 are important pathogens that pose a threat to the ...
Sharanagouda Patil
doaj   +1 more source

Efficient generation of recombinant RNA viruses using targeted recombination-mediated mutagenesis of bacterial artificial chromosomes containing full-length cDNA [PDF]

, 2013
BACKGROUND: Infectious cDNA clones are a prerequisite for directed genetic manipulation of RNA viruses. Here, a strategy to facilitate manipulation and rescue of classical swine fever viruses (CSFVs) from full-length cDNAs present within bacterial ...
Beer, Martin, Belsham, Graham, Fahnøe, Ulrik, Friis, Martin Barfred, Höper, Dirk, Rasmussen, Thomas Bruun, Reimann, Ilona, Risager, Peter Christian   +7 more
core   +3 more sources

PCBP1 Deficient Pigs Hold the Potential to Inhibit CSFV Infection [PDF]

, 2021
AbstractClassical swine fever virus (CSFV), pathogen of classic swine fever, has caused severe economic losses worldwide. Poly (rC)-binding protein 1 (PCBP1), interacting with Npro of CSFV, plays a vital role in CSFV growth. Here, our research is the first report to generate PCBP1 knockout pigs via gene editing technology.
Chunyun Qi, Daxin Pang, Kang Yang, Shuyu Jiao, Heyong Wu, Chuheng Zhao, Lanxin Hu, Feng Li, Jian Zhou, Lin Yang, Dongmei Lv, Xiaochun Tang, Hongsheng Ouyang, Zicong Xie   +13 more
openaire   +1 more source

Classical Swine Fever Virus Infection and Its NS4A Protein Expression Induce IL-8 Production through MAVS Signaling Pathway in Swine Umbilical Vein Endothelial Cells

Frontiers in Microbiology, 2018
Classical swine fever virus (CSFV) infection causes a severe disease of pigs, which is characterized by hemorrhage, disseminated intravascular coagulation, and leucopenia. IL-8, a main chemokine and activator of neutrophils, regulates the permeability of
Wang Dong, Huifang Lv, Kangkang Guo, Tao Wang, Yueling Ouyang, Mingxing Jin, Yanming Zhang   +6 more
doaj   +1 more source

Anti-Classical Swine Fever Virus Strategies

Microorganisms, 2021
Classical swine fever (CSF), caused by CSF virus (CSFV), is a highly contagious swine disease with high morbidity and mortality, which has caused significant economic losses to the pig industry worldwide. Biosecurity measures and vaccination are the main
Jindai Fan, Yingxin Liao, Mengru Zhang, Chenchen Liu, Zhaoyao Li, Yuwan Li, Xiaowen Li, Keke Wu, Lin Yi, Hongxing Ding, Mingqiu Zhao, Shuangqi Fan, Jinding Chen   +12 more
doaj   +1 more source

Tumor Necrosis Factor Receptor-Associated Factor 5 Interacts with the NS3 Protein and Promotes Classical Swine Fever Virus Replication

Viruses, 2018
Classical swine fever, caused by classical swine fever virus (CSFV), is a highly contagious and high-mortality viral disease, causing huge economic losses in the swine industry worldwide.
Huifang Lv, Wang Dong, Kangkang Guo, Mingxing Jin, Xiaomeng Li, Cunfa Li, Yanming Zhang   +6 more
doaj   +1 more source

Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever Virus and Border Disease Virus

Viruses, 2021
Classical swine fever virus (CSFV) shares high structural and antigenic homology with bovine viral diarrhea virus (BVDV) and border disease virus (BDV).
Yu-Liang Huang, Denise Meyer, Alexander Postel, Kuo-Jung Tsai, Hsin-Meng Liu, Chia-Huei Yang, Yu-Chun Huang, Nicholas Berkley, Ming-Chung Deng, Fun-In Wang, Paul Becher, Helen Crooke, Chia-Yi Chang   +12 more
doaj   +1 more source