Results 21 to 30 of about 3,812 (175)

Attachment, Entry, and Intracellular Trafficking of Classical Swine Fever Virus

Viruses, 2023
Classical swine fever virus (CSFV), which is a positive-sense, single-stranded RNA virus with an envelope, is a member of the Pestivirus genus in the Flaviviridae family.
Xin Guo, Maolin Zhang, Xiaomin Liu, Yannan Zhang, Chongyang Wang, Yidi Guo   +5 more
doaj   +1 more source

LDHB inhibition induces mitophagy and facilitates the progression of CSFV infection [PDF]

Autophagy, 2020
Cellular metabolism caters to the energy and metabolite needs of cells. Although the role of the terminal metabolic enzyme LDHB (lactate dehydrogenase B) in the glycolysis pathway has been widely studied in cancer cells, its role in viral infection is relatively unknown.
Shuangqi, Fan, Keke, Wu, Mingqiu, Zhao, Jin, Yuan, Shengming, Ma, Erpeng, Zhu, Yuming, Chen, Hongxing, Ding, Lin, Yi, Jinding, Chen   +9 more
openaire   +2 more sources

Self-Assembling Nanovaccine Enhances Protective Efficacy Against CSFV in Pigs [PDF]

Frontiers in Immunology, 2021
Classical swine fever virus (CSFV) is a highly contagious pathogen, which pose continuous threat to the swine industry. Though most attenuated vaccines are effective, they fail to serologically distinguish between infected and vaccinated animals, hindering CSFV eradication.
Ze-Hui Liu, Hui-Ling Xu, Guang-Wei Han, Li-Na Tao, Ying Lu, Su-Ya Zheng, Wei-Huan Fang, Wei-Huan Fang, Fang He, Fang He   +9 more
openaire   +3 more sources

Evaluation of antibody and antigen cross-reaction in Kenyan dairy cattle naturally infected with two pestiviruses: Bovine viral diarrhea virus and classical swine fever virus [PDF]

Veterinary World, 2022
Background and Aim: Bovine viral diarrhea virus (BVDV) and classical swine fever virus (CSFV) are important pathogens of cattle and pigs, respectively, and belong to the genus Pestivirus.
Daniel Muasya, John Van Leeuwen, George Gitau, Shawn McKenna, Luke Heider, Joan Muraya   +5 more
doaj   +1 more source

Activation of Interleukin-1β Release by the Classical Swine Fever Virus Is Dependent on the NLRP3 Inflammasome, Which Affects Virus Growth in Monocytes

Frontiers in Cellular and Infection Microbiology, 2018
Classical swine fever virus (CSFV) is a classic Flavivirus that causes the acute, febrile, and highly contagious disease known as classical swine fever (CSF).
Shuangqi Fan, Jin Yuan, Shaofeng Deng, Yuming Chen, Baoming Xie, Keke Wu, Mengjiao Zhu, Hailuan Xu, Yunzhen Huang, Jiongfeng Yang, Yangyi Zhang, Jinding Chen, Mingqiu Zhao   +12 more
doaj   +1 more source

A prospective CSFV-PCV2 bivalent vaccine effectively protects against classical swine fever virus and porcine circovirus type 2 dual challenge and prevents horizontal transmission

Veterinary Research, 2023
Classical swine fever virus (CSFV) infection leading to CSF outbreaks is among the most devastating swine diseases in the pig industry. Porcine circovirus type 2 (PCV2) infection, resulting in porcine circovirus-associated disease (PCVAD), is also a ...
Jing-Yuan Chen, Chi-Ming Wu, Min-Yuan Chia, Chienjin Huang, Maw-Sheng Chien   +4 more
doaj   +1 more source

MiR-140 inhibits classical swine fever virus replication by targeting Rab25 in swine umbilical vein endothelial cells

Virulence, 2020
Classical swine fever virus (CSFV) is one of the most important viral pathogens leading worldwide threats to pig industry. MicroRNAs (miRNAs) play important roles in regulating virus replication, but whether miRNAs affect CSFV infection is still poorly ...
Panpan Xu, Shuangkai Jia, Kai Wang, Zhixin Fan, Hongqing Zheng, Jiangman Lv, Yanfen Jiang, Yufeng Hou, Bihao Lou, Hongchao Zhou, Yanming Zhang, Kangkang Guo   +11 more
doaj   +1 more source

Influence of NS5A protein of classical swine fever virus (CSFV) on CSFV internal ribosome entry site-dependent translation

Journal of General Virology, 2009
An internal ribosome entry site (IRES) present in the 5′ untranslated region (UTR) promotes translation of classical swine fever virus (CSFV) genomes. Using anin vitrosystem with monocistronic reporter RNA containing the CSFV 5′UTR, this study found that CSFV NS5A decreased CSFV IRES-mediated translation in a dose-dependent manner.
Ming, Xiao, Yujing, Wang, Zailing, Zhu, Jialin, Yu, Lingzhu, Wan, Jun, Chen   +5 more
openaire   +2 more sources

CO-INFECTIONS OF CLASSICAL SWINE FEVER VIRUS, PORCINE SAPELOVIRUS AND PORCINE CIRCOVIRUS 2 IN DIARRHEIC PIGLETS: EVIDENCE FROM KARNATAKA, INDIA [PDF]

Exploratory Animal and Medical Research
Suckling and weaned piglets suffering from gastrointestinal disorders often develop diarrhea due to viral co-infections. Classical swine fever virus, porcine sapelovirus, and porcine circovirus type 2 are important pathogens that pose a threat to the ...
Sharanagouda Patil
doaj   +1 more source

RPLP1, an NS4B-interacting protein, enhances production of CSFV through promoting translation of viral genome

Virulence, 2022
Classical swine fever virus (CSFV), the etiological agent of classical swine fever (CSF), causes serious financial losses to the pig industry. Using yeast two-hybrid screening, we have previously identified ribosomal protein RPLP1 as a potential binding ...
Longxiang Zhang, Jihui Lin, Maoyang Weng, Ying Wen, Yanming Zhang, Wen Deng   +5 more
doaj   +1 more source