Results 11 to 20 of about 6,850 (217)
Dual NDP52 Function in Persistent CSFV Infection [PDF]
Frontiers in Microbiology, 2020 Viruses have evolved many mechanisms to escape host antiviral responses. Previously, we found that classical swine fever virus (CSFV) infection induces autophagy using the autophagosome as a self-replication site, thereby evading the host immune response
Shuangqi Fan +13 more
doaj +3 more sources
Characterization of a Cytopathogenic Reporter CSFV [PDF]
Viruses, 2021 Cytopathogenic (cp) pestiviruses frequently emerge in cattle that are persistently infected with the bovine viral diarrhea virus (BVDV) as a consequence of RNA recombination and mutation. They induce apoptosis in infected tissue cultures, are highly attenuated in the immunocompetent host, and unable to establish persistent infections after diaplacental
Reuscher, Carina +4 more
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Establishment and Evaluation of a Multicolor Latex Microsphere-Based Lateral Flow Immunoassay for the Simultaneous Detection of Antibodies Against African and Classical Swine Fever Viruses. [PDF]
Transbound Emerg DisAfrican swine fever (ASF), a highly fatal disease often termed the “number one killer” of pigs, presents clinical symptoms indistinguishable from classical swine fever (CSF), such as fever, diarrhea, and vomiting, complicating on‐site differential diagnosis.
Chen J +13 more
europepmc +2 more sources
CSFV proliferation is associated with GBF1 and Rab2 [PDF]
Journal of Biosciences, 2016 The Golgi apparatus and its resident proteins are utilized and regulated by viruses to facilitate their proliferation. In this study, we investigated Classical swine fever virus (CSFV) proliferation when the function of the Golgi was disturbed. Golgi function was disturbed using chemical inhibitors, namely, brefeldin A (BFA) and golgicide A (GCA), and ...
Liang, Wulong +3 more
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Virology Journal, 2021 Classical swine fever (CSF) caused by the classical swine fever virus (CSFV) is a highly contagious swine disease resulting in large economical losses worldwide.
Qiang Wei +9 more
doaj +1 more source
Self-Assembling Nanovaccine Enhances Protective Efficacy Against CSFV in Pigs [PDF]
Frontiers in Immunology, 2021 Classical swine fever virus (CSFV) is a highly contagious pathogen, which pose continuous threat to the swine industry. Though most attenuated vaccines are effective, they fail to serologically distinguish between infected and vaccinated animals, hindering CSFV eradication.
Ze-Hui Liu +9 more
openaire +3 more sources
Viruses, 2023 Classical swine fever (CSF) remains one of the most economically significant viral diseases affecting domestic pigs and wild boars worldwide. To develop a safe and effective vaccine against CSF, we have constructed a triple gene-deleted pseudorabies virus (PRVtmv)-vectored bivalent subunit vaccine against porcine circovirus type 2b (PCV2b) and CSFV ...
Ediane Silva +5 more
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Emerging Microbes and Infections, 2020 Classical swine fever virus (CSFV) is a member of the genus Pestivirus in the Flaviviridae family. To date, the host factors required for CSFV entry remain poorly characterized.
Guanglai Zheng +12 more
doaj +1 more source
Lactate facilitates classical swine fever virus replication by enhancing cholesterol biosynthesis
iScience, 2022 Summary: An emerging topic in virology is that viral replication is closely linked with the metabolic reprogramming of host cells. Understanding the effects of reprogramming host cell metabolism due to classical swine fever virus (CSFV) infection and the
Xiaodong Zou +9 more
doaj +1 more source
Transcriptome analysis of PK-15 cells expressing CSFV NS4A
BMC Veterinary Research, 2022 Abstract Background Classical swine fever (CSF) is a severe disease of pigs that results in huge economic losses worldwide and is caused by classical swine fever virus (CSFV). CSFV nonstructural protein 4 A (NS4A) plays a crucial role in infectious CSFV particle formation.
Huifang Lv +6 more
openaire +3 more sources