Results 31 to 40 of about 3,801 (175)

Transcriptome analysis of PK-15 cells expressing CSFV NS4A

BMC Veterinary Research, 2022
Abstract Background Classical swine fever (CSF) is a severe disease of pigs that results in huge economic losses worldwide and is caused by classical swine fever virus (CSFV). CSFV nonstructural protein 4 A (NS4A) plays a crucial role in infectious CSFV particle formation.
Huifang Lv, Zhifeng Peng, Bingxin Jia, Huiyuan Jing, Sufang Cao, Zhikun Xu, Wang Dong   +6 more
openaire   +3 more sources

Virus Adaptation and Selection Following Challenge of Animals Vaccinated against Classical Swine Fever Virus

Viruses, 2019
Vaccines against classical swine fever have proven very effective in protecting pigs from this deadly disease. However, little is known about how vaccination impacts the selective pressures acting on the classical swine fever virus (CSFV).
Ulrik Fahnøe, Anders Gorm Pedersen, Camille Melissa Johnston, Richard J. Orton, Dirk Höper, Martin Beer, Jens Bukh, Graham J. Belsham, Thomas Bruun Rasmussen   +8 more
doaj   +1 more source

A prospective CSFV-PCV2 bivalent vaccine effectively protects against classical swine fever virus and porcine circovirus type 2 dual challenge and prevents horizontal transmission

Veterinary Research, 2023
Classical swine fever virus (CSFV) infection leading to CSF outbreaks is among the most devastating swine diseases in the pig industry. Porcine circovirus type 2 (PCV2) infection, resulting in porcine circovirus-associated disease (PCVAD), is also a ...
Jing-Yuan Chen, Chi-Ming Wu, Min-Yuan Chia, Chienjin Huang, Maw-Sheng Chien   +4 more
doaj   +1 more source

Induction of autophagy and suppression of type I IFN secretion by CSFV

Autophagy, 2020
Macroautophagy/autophagy plays an essential role in cellular responses to pathogens. However, the precise mechanisms and signaling pathways that modulate cellular autophagy in classical swine fever virus (CSFV)-infected host cells have not been confirmed.
Baoming, Xie, Mingqiu, Zhao, Dan, Song, Keke, Wu, Lin, Yi, Wenhui, Li, Xiaoming, Li, Kun, Wang, Jinding, Chen   +8 more
openaire   +3 more sources

AIF1 was identified as an up-regulated gene contributing to CSFV Shimen infection in porcine alveolar macrophage 3D4/21 cells [PDF]

PeerJ, 2020
Classical swine fever (CSF) is a disease that is characterized by diffuse hemorrhaging, high fever, and high mortality rates. The pro-inflammatory characteristics of allograft inflammatory factor 1 (AIF1) have been well documented; however, insufficient ...
Xiaocheng Gong, Xuepeng Li, Xin You, Aoxue Hu, Min Liu, Huimin Yao, Jun He, Xianghan Zhang, Pengbo Ning   +8 more
doaj   +2 more sources

CSFV induced mitochondrial fission and mitophagy to inhibit apoptosis

Oncotarget, 2017
Classical swine fever virus (CSFV), which causes typical clinical characteristics in piglets, including hemorrhagic syndrome and immunosuppression, is linked to hepatitis C and dengue virus. Oxidative stress and a reduced mitochondrial transmembrane potential are disturbed in CSFV-infected cells.
Gou, Hongchao, Zhao, Mingqiu, Xu, Hailuan, Yuan, Jin, He, Wencheng, Zhu, Mengjiao, Ding, Hongxing, Yi, Lin, Chen, Jinding   +8 more
openaire   +3 more sources

CO-INFECTIONS OF CLASSICAL SWINE FEVER VIRUS, PORCINE SAPELOVIRUS AND PORCINE CIRCOVIRUS 2 IN DIARRHEIC PIGLETS: EVIDENCE FROM KARNATAKA, INDIA [PDF]

Exploratory Animal and Medical Research
Suckling and weaned piglets suffering from gastrointestinal disorders often develop diarrhea due to viral co-infections. Classical swine fever virus, porcine sapelovirus, and porcine circovirus type 2 are important pathogens that pose a threat to the ...
Sharanagouda Patil
doaj   +1 more source

Influence of PPV, PRV and PRRSV on Efficacy of the Lapinized Hog Cholera Vaccine and Pathogenicity of Classical swine fever virus

Journal of Integrative Agriculture, 2012
Classical swine fever caused by Classical swine fever virus (CSFV) is a serious problem for swine industries in developing countries, which successful control of the disease have been relying on vaccination. However, classical swine fever still occurs in
Yi-bao NING, Yun ZHAO, Qin WANG, Xue-zheng FAN, Yu-ming QIN, Guang-chuan ZHANG, Lu XU, Hui-shen QIU, Zai-shi WANG, Li SONG, Qing-chun SHEN, Qi-zu ZHAO   +11 more
doaj   +1 more source

Classical Swine Fever Virus Infection and Its NS4A Protein Expression Induce IL-8 Production through MAVS Signaling Pathway in Swine Umbilical Vein Endothelial Cells

Frontiers in Microbiology, 2018
Classical swine fever virus (CSFV) infection causes a severe disease of pigs, which is characterized by hemorrhage, disseminated intravascular coagulation, and leucopenia. IL-8, a main chemokine and activator of neutrophils, regulates the permeability of
Wang Dong, Huifang Lv, Kangkang Guo, Tao Wang, Yueling Ouyang, Mingxing Jin, Yanming Zhang   +6 more
doaj   +1 more source

Anti-Classical Swine Fever Virus Strategies

Microorganisms, 2021
Classical swine fever (CSF), caused by CSF virus (CSFV), is a highly contagious swine disease with high morbidity and mortality, which has caused significant economic losses to the pig industry worldwide. Biosecurity measures and vaccination are the main
Jindai Fan, Yingxin Liao, Mengru Zhang, Chenchen Liu, Zhaoyao Li, Yuwan Li, Xiaowen Li, Keke Wu, Lin Yi, Hongxing Ding, Mingqiu Zhao, Shuangqi Fan, Jinding Chen   +12 more
doaj   +1 more source