Results 71 to 80 of about 3,812 (175)

The recombinant Erns and truncated E2-based indirect enzyme-linked immunosorbent assays to distinguishably test specific antibodies against classical swine fever virus and bovine viral diarrhea virus

Virology Journal, 2022
Background Classical swine fever (CSF) virus is the causative agent of an economically important, highly contagious disease of pigs. CSFV is genetically and serologically related to bovine viral diarrhea virus (BVDV). BVDV infection in pigs can mimic CSF
Weicheng Yi, Hongchang Zhu, Yihan Wu, Qingmei Li, Wange Lou, Haizhong Zhao, Zishu Pan   +6 more
doaj   +1 more source

Development of Magnetic Particle–Based Chemiluminescence Immunoassays for Detecting PCV2 VLP‐ and Rep‐Specific Antibodies and Their Combined Use for Immune Evaluation and Replication‐Associated Exposure Assessment

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Porcine circovirus 2 (PCV2) remains a major swine pathogen, and interpretation of capsid protein (Cap)–based serology is challenging in vaccinated populations because vaccine‐induced Cap antibodies overlap with replication‐associated serological signals.
Mingxi Gou, Xiaoqing Song, Jie Fan, Zhixiong Chen, Zihao Kuang, Mengyao Lu, Zhongxin Fan, Meng Ge, Zhong Peng   +8 more
wiley   +1 more source

Functionality of Chimeric E2 Glycoproteins of BVDV and CSFV in Virus Replication

Virology: Research and Treatment, 2008
An intriguing difference between the E2 glycoprotein of CSFV and the other groups of pestiviruses (nonCSFV) is a lack of two cysteine residues on positions cysteine 751 and 798. Other groups of pestivirus are not restricted to one species as swine, whereas CSFV is restricted to swine and wild boar. We constructed chimeric CSFV/BVDV E2 genes based on a
van Gennip, H.G.P., Miedema, G.K.W., Moormann, R.J.M., van Rijn, P.A.   +3 more
openaire   +2 more sources

Emerging Challenges and Advances in Porcine Circovirus: A Decade in Review

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Over the past decade, porcine circoviruses (PCVs) have continued to pose a significant threat to global swine health, and pivotal discoveries have significantly reshaped our understanding of their biology and control. Extensive genomic surveillance has expanded porcine circovirus 2 (PCV2) genotyping from four to at least eight lineages, with PCV2d now ...
Jiawei Zheng, Guoqing Zhang, Peiheng Li, Linzhu Ren, Nan-hua Chen   +4 more
wiley   +1 more source

Isolation and Pathogenicity of a Getah Virus With a Novel Deletion in the 3′ UTR

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The spread of Getah virus (GETV) in China has become increasingly severe due to long‐term neglect and the lack of vaccines, posing a threat to animal safety and public health. In this study, we isolated and identified a novel GETV strain, designated GETV‐CX7.
Yawei Sun, Haiyan Li, Wenxu Wang, Yaqing Shi, Dongzhuo Yang, Yingshuo Zhang, Jimei Du, Yongtao Li, Linyang Yu, Xianfeng Zhang, Lu Chen, Zu Zhang Wei   +11 more
wiley   +1 more source

Detection of Phocoena Pestivirus and Neutralizing Antibodies in Harbor Porpoises Found Dead at the North Sea and Baltic Sea Coasts

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
In 2019, a marine pestivirus, Phocoena pestivirus (PhoPeV), family Pestiviridae, was described for the first time. To date, the impact of PhoPeV infections on harbor porpoises is still unknown. Therefore, a screening study was carried out on harbor porpoises found dead on the German North Sea and Baltic Sea coasts during 2021–2025.
Lars Söder, Denise Meyer, Nele Gremmel, Alexander Postel, Ursula Siebert, Luca Aroha Schick, Stephanie Groß, Jens Brackmann, Christine Baechlein, Benjamin Lamp, Till Rümenapf, Paul Becher, Nan-hua Chen   +12 more
wiley   +1 more source

Computational investigation in inhibitory effects of amantadine on classical swine fever virus p7 ion channel activity

Scientific Reports
Classical swine fever virus (CSFV) p7 viroporin plays crucial roles in cellular ion balance and permeabilization. The antiviral drug amantadine effectively inhibits viral replication by blocking the activity of CSFV p7 viroporin.
Xiaowei Chen, Xiao Wang
doaj   +1 more source

Antiviral Role of IFITM Proteins in Classical Swine Fever Virus Infection

Viruses, 2019
The proteins IFITM1, IFITM2, and IFITM3 are host effectors against a broad range of RNA viruses whose roles in classical swine fever virus (CSFV) infection had not yet been reported.
Cheng Li, Hongqing Zheng, Yifan Wang, Wang Dong, Yaru Liu, Liang Zhang, Yanming Zhang   +6 more
doaj   +1 more source

Classical swine fever virus (CSFV) envelope glycoprotein E2 containing one structural antigenic unit protects pigs from lethal CSFV challenge

Journal of General Virology, 1996
Envelope glycoprotein E2, formerly called E1 or gp51-54, of classical swine fever virus (CSFV) expressed in insect cells protects swine from classical swine fever. Monoclonal antibodies directed against epitopes of domains B and C and subdomain A1 are neutralizing.
van Rijn, P.A., Bossers, A., Wensvoort, G., Moormann, R.J.M.   +3 more
openaire   +3 more sources

mTORC1 Negatively Regulates the Replication of Classical Swine Fever Virus Through Autophagy and IRES-Dependent Translation

iScience, 2018
Summary: Classical swine fever virus (CSFV) can utilize diverse host signaling pathways for its replication; however, the cross talk between mammalian target of rapamycin (mTOR) and CSFV remains unknown.
Qinghua Luo, Li Zhang, Feng Wei, Qiang Fang, Fei Bao, Shijiang Mi, Nan Li, Chengming Wang, Yan Liu, Changchun Tu   +9 more
doaj   +1 more source