Results 81 to 90 of about 6,850 (217)

Antiviral Role of Serine Incorporator 5 (SERINC5) Proteins in Classical Swine Fever Virus Infection

Frontiers in Microbiology, 2020
Serine incorporator 5 (SERINC5), a multipass transmembrane protein, protects cells from viral infections. The mechanism by which SERINC5 protects against classical swine fever virus (CSFV) infection is unknown. In this study, overexpression of SERINC5 in
Wenhui Li, Wenhui Li, Zilin Zhang, Zilin Zhang, Liangliang Zhang, Liangliang Zhang, Hong Li, Shuangqi Fan, Shuangqi Fan, Erpeng Zhu, Erpeng Zhu, Jindai Fan, Jindai Fan, Zhaoyao Li, Zhaoyao Li, Wenxian Chen, Wenxian Chen, Lin Yi, Lin Yi, Hongxing Ding, Hongxing Ding, Jinding Chen, Jinding Chen, Mingqiu Zhao, Mingqiu Zhao   +24 more
doaj   +1 more source

Establishment and Application of a Novel Protein Microarray for Serological Detection and Differentiation of Senecavirus A

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Senecavirus A (SVA) is an emerging swine pathogen that causes vesicular disease, which presents clinically indistinguishable signs from other vesicular diseases. To enable differentiation of infected from vaccinated animals (DIVA), we developed a novel protein microarray for dual serological detection of antibodies against SVA structural (VP2‐VP3‐VP1 ...
Dexin Li, Junhua Deng, Zenglin Wang, Yunjing Zhang, Yufang Li, Liying Hao, Kegong Tian, Xiangdong Li, Linzhu Ren   +8 more
wiley   +1 more source

Short communication: Stability and integrity of classical swine fever virus RNA stored at room temperature

Spanish Journal of Agricultural Research, 2017
Worldwide cooperation between laboratories working with classical swine fever virus (CSFV) requires exchange of virus isolates. For this purpose, shipment of CSFV RNA is a safe alternative to the exchange of infectious material.
Damarys Relova, Lester J. Pérez, Liliam Ríos, Liani Coronado, Yoandry Hinojosa, Ana M. Acevedo, María T. Frías, Carmen L. Perera   +7 more
doaj   +1 more source

A Novel In‐Cell ELISA With Superior Sensitivity and Specificity for the Detection of African Swine Fever Virus‐Specific IgM and IgG Antibodies

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF), a high‐profile transboundary animal disease caused by ASF virus (ASFV), imposes a devastating impact on the global swine industry. Given that vaccines are still under development, including field evaluations, early detection of ASFV is crucial for effective disease control and mitigation.
Ping Wu, Aric J. McDaniel, Yelitza Y. Rodríguez, Vivian O’Donnell, Wei Jia, Nan-hua Chen   +5 more
wiley   +1 more source

Immunomodulatory effect of swine CCL20 chemokine in DNA vaccination against CSFV

Veterinary Immunology and Immunopathology, 2011
The objective of this work was to explore whether a plasmid expressing CCL20 chemokine could improve the immune response against CSFV in co-administration with a DNA vaccine expressing the E2 protein. The immunization of pigs with the DNA vaccine formulation, that contains swine CCL20 chemokine, resulted in the homogenous induction of detectable levels
Tarradas, J., Álvarez, B., Fraile, L., Rosell, R., Muñoz, M., Galindo-Cardiel, I., Domingo, M., Dominguez, J., Ezquerra, A., Sobrino, F., Ganges, L.   +10 more
openaire   +3 more sources

Research review on non-structural protein 3 (ns3) of classical swine fever virus and its potential applications in vaccine development [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi
Classical Swine Fever Virus (CSFV) is a virus that poses a serious threat to the pig farming industry, and its non-structural protein 3 (NS3) plays a key role in the virus"s replication, pathogenicity, and immune evasion.
Hai-Yang YU, Dong-Mei GAO, Jun ZHAO
doaj   +1 more source

In planta production of two peptides of the Classical Swine Fever Virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X [PDF]

, 2006
Background Classical Swine Fever (CSFV) is one of the most important viral infectious diseases affecting wild boars and domestic pigs. The etiological agent of the disease is the CSF virus, a single stranded RNA virus belonging to the family ...
Marconi, Gianpiero, Albertini, Emidio, Barone, Pierluigi, De Marchis, Francesca, Lico, Chiara, Marusic, Carla, Rutili, Domenico, Veronesi, Fabio, Porceddu, Andrea   +8 more
core   +1 more source

Detection of African Swine Fever Virus (ASFV) in Haematopinus suis: Evidence for a Potential New Sylvatic Cycle of ASFV Involving Lice and Domestic Pigs

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
African swine fever (ASF) is a lethal and highly contagious viral disease of domestic and wild pigs, listed as a notifiable disease to the World Organization for Animal Health (WOAH). In the absence of any credible commercially available vaccine, the economic losses to the global pig industry inflicted by ASF is insurmountable.
Tridib Kumar Rajkhowa, Kiran Jayappa, A. Z. Beithatlo, Charitha B. Balakrishna, Laldinliana Khiangte, Guillermo R. Risatti, Nan-hua Chen   +6 more
wiley   +1 more source

Mutation-induced changes of transmembrane pore size revealed by combined ion-channel conductance and single vesicle permeabilization analyses [PDF]

, 2018
Permeabilization of the Endoplasmic Reticulum (ER) is instrumental in the progression of host-cell infection by many viral pathogens. We have described that permeabilization of ER model membranes by the pore-forming domain of the Classical Swine Fever ...
Aguilella, Vicente, Alcaraz, Antonio, Borca, Manuel V., Gladue, Douglas, Largo, Eneko, Nieva, José L., Torralba, Johana   +6 more
core   +2 more sources

Dapagliflozin restores odour‐induced functional integration of primary olfactory cortex circuit but not olfactory‐related regional brain activation in patients with type 2 diabetes: A 16‐week randomised comparative study

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7309-7322, December 2025.
Abstract Aims Although some hypoglycaemic agents have been suggested to possess neuroprotective effects, their mechanisms and efficacy remain controversial. We aimed to investigate the effects of dapagliflozin, liraglutide or acarbose treatment on the directed functional connectivity (FC) of the primary olfactory cortex (POC) circuit and regional ...
Xin Li, Yi Zhang, Yan Bi, Jiaming Lu, Zhou Zhang, Cheng Ji, Xin Zhang, Qian Li, Shuang Wang, Jiu Chen, Zhengyang Zhu, Wen Zhang, Bing Zhang   +12 more
wiley   +1 more source