Detection of csgA gene in carbapenem-resistant Acinetobacter baumannii strains and targeting with Ocimum sanctum biocompounds [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Carbapenem-resistant Acinetobacter baumannii (CRAB) is considered highly virulent due to csgA gene-mediated biofilm formation. The present study aimed to target the same gene, employing the antibiofilm effect of Ocimum sanctum (O.
Saishree Anchana R +3 more
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The function of a conidia specific transcription factor CsgA in Aspergillus nidulans [PDF]
Scientific Reports, 2022 Aspergillus spp. mainly reproduce asexually via asexual spores called conidia. In this study, we identified CsgA, a conidia-specific Zn2Cys6 transcription factor containing the GAL4-like zinc-finger domain, and characterized the roles of CsgA in the ...
He-Jin Cho, Hee-Soo Park
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Structural insight into Escherichia coli CsgA amyloid fibril assembly
mBioThe discovery of functional amyloids in bacteria dates back several decades, and our understanding of the Escherichia coli curli biogenesis system has gradually expanded over time.
Fan Bu, Derek R. Dee, Bin Liu
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A novel recombinant chimeric bio-adhesive protein consisting of mussel foot protein 3, 5, gas vesicle protein A, and CsgA curli protein expressed in Pichia pastoris [PDF]
AMB Express, 2022 Keypoints A chimeric bioinspired adhesive protein has been generated for use in wet condition Enhanced adhesion strength of chimeric protein due to the curli proteins GvpA and CsgA Amyloid structure of GvpA and CsgA led to efficient self-assembly of ...
Nazanin Bolghari +3 more
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Modified recombinant collagen-peptide/gallic acid grafted chitosan composites with antibacterial and antioxidant property for wound dressing: a preliminary study [PDF]
Frontiers in ImmunologyChronic wounds pose a persistent clinical challenge, primarily due to prolonged bacterial infections. The development of natural antibacterial dressings offers a promising strategy for their effective management. In this study, recombinant human collagen
Yu Chen +11 more
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E.coli-derived CsgA-peptides stimulate cytokine production in microglia and lead to transient changes in neocortical Aβ-levels in pre-plaque APPSWE/PS1ΔE9 and wild type mice [PDF]
Brain, Behavior, & Immunity - HealthEpidemiological and pre-clinical data propose that infections can accelerate the cognitive decline in Alzheimer's disease (AD) and other dementias.
Leda Mygind +11 more
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Transcriptomic analysis of Myxococcus xanthus csgA, fruA, and mrpC mutants reveals extensive and diverse roles of key regulators in the multicellular developmental process [PDF]
BMC GenomicsBackground The bacterium Myxococcus xanthus provides an important multicellular model for understanding stress responses. The regulatory proteins CsgA, FruA, and MrpC are essential to survive prolonged starvation by forming fruiting bodies, which are ...
Mark A. Farrugia +2 more
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Genetically Programmed Single‐Component Protein Hydrogel for Spinal Cord Injury Repair [PDF]
Advanced ScienceProtein self‐assembly allows for the formation of diverse supramolecular materials from relatively simple building blocks. In this study, a single‐component self‐assembling hydrogel is developed using the recombinant protein CsgA, and its successful ...
Yi Wei +7 more
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Short-range C-signaling restricts cheating behavior during Myxococcus xanthus development [PDF]
mBioMyxococcus xanthus uses short-range C-signaling to coordinate multicellular mound formation with sporulation during fruiting body development.
Y. Hoang +3 more
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The cytoplasmic protein YedX is a potent inhibitor of CsgA amyloid assembly in E. coli. [PDF]
J Biol ChemGurnani B, Jain N.
europepmc +2 more sources