CsgA, a putative signal molecule of the myxobacterium Stigmatella aurantiaca involved in fruiting : characterization of the csgA gene and influence of csgA inactivation on development [PDF]
Cell-cell interaction is a prerequisite for multi-cellular development and cellular differentiation of the Gram-negative bacterium Stigmatella aurantiaca. For the elucidation of the temporal and spatial coordination of the physiology and motility of the cells during development, isolation and characterization of molecules involved in cell-cell ...
Milosevic, Ana
openaire +3 more sources
Structural insight into Escherichia coli CsgA amyloid fibril assembly
The discovery of functional amyloids in bacteria dates back several decades, and our understanding of the Escherichia coli curli biogenesis system has gradually expanded over time.
Fan Bu, Derek R. Dee, Bin Liu
doaj +3 more sources
Human Fibrinogen Inhibits Amyloid Assembly of Biofilm-Forming CsgA
Curli is a biofilm-forming amyloid that is expressed on the surface of Gram-negative enteric bacteria such as Escherichia coli and Salmonella spp. Curli is primarily composed of the major structural subunit, CsgA, and interacts with a wide range of human proteins that contribute to bacterial virulence.
Hema M. Swasthi +3 more
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NMR insights into the pre-amyloid ensemble and secretion targeting of the curli subunit CsgA [PDF]
AbstractThe biofilms of Enterobacteriaceae are fortified by assembly of curli amyloid fibres on the cell surface. Curli not only provides structural reinforcement, but also facilitates surface adhesion. To prevent toxic intracellular accumulation of amyloid precipitate, secretion of the major curli subunit, CsgA, is tightly regulated.
Sewell, L +5 more
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Structural predictions for curli amyloid fibril subunits CsgA and CsgB
CsgA are the building blocks of curli fibrils.
E. P. DeBenedictis, D. Ma, S. Keten
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CsgA Production by Escherichia coli O157:H7 Alters Attachment to Abiotic Surfaces in Some Growth Environments [PDF]
ABSTRACT The role of curli expression in attachment of Escherichia coli O157:H7 to glass, Teflon, and stainless steel (SS) was investigated through the creation of csgA knockout mutants in two isolates of E. coli O157:H7.
Goulter-Thorsen, R. +4 more
core +8 more sources
CSGA: A DUAL POPULATION GENETIC ALGORITHM BASED ON MEXICAN CAVEFISH GENETIC DIVERSITY
Genetic algorithms (GAs) are search algorithms based on population genetics and natural selection concepts. Maintaining population variety in GAs is critical for ensuring global exploration and mitigating the risks of premature convergence.
Esra'a Alkafaween +3 more
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De Novo Autogenic Engineered Living Functional Materials. [PDF]
A versatile platform for de novo autogenic engineered living materials is presented, leveraging protein mining, computational modeling, and synthetic biology. By reprogramming the Escherichia coli curli machinery with β‐solenoid proteins from non‐model bacteria, macroscopic biomaterials with enhanced mechanical properties, UV‐C irradiation protection ...
Hammad HM +9 more
europepmc +2 more sources
Die Kristallstruktur von CsGaS2 / The Crystal Structure of CsGaS2 [PDF]
Colourless needles of the compound CsGaS2 were obtained by the reaction of cesium carbonate with gallium oxide at 850°C under a stream of H2S. Structural investigations of (100) twinned crystals revealed an atomic arrangement isotypical with RbFeS2. Space group C2/c; a = 7.425(6) Å, b = 12.21(1) Å, c = 5.907(6) Å, β = 113.1(1)°; z = 4.
Dieter Schmitz, Welf Bronger
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The cytoplasmic protein YedX is a potent inhibitor of CsgA amyloid assembly in E. coli. [PDF]
Functional amyloids are a class of amyloids that serve important biological functions. One such bacterial functional amyloid is curli, assembled on the cell surface by Escherichia coli during biofilm biogenesis. Curli precursor proteins, CsgA and CsgB, synthesized in the cytoplasm, are highly amyloidogenic.
Gurnani B, Jain N.
europepmc +4 more sources

