Results 1 to 10 of about 6,556 (206)
Biomolecules, 2018 Escherichia coli strains may be beneficial or pathogenic. Many E. coli strains that cause human disease, especially those responsible for bacteremia and sepsis, express virulence factors that impart resistance to the complement system.
Çağla Tükel +2 more
exaly +4 more sources
Journal of Food Protection, 2023 Escherichia coli O157:H7 expresses extracellular proteins called curli that are essential for surface colonization. Transfer rates of E. coli O157:H7 0018+ (curli+), and 0018- (curli−) from inoculated to noninoculated lettuce pieces during washing were ...
Ann Charles Vegdahl, Donald W. Schaffner
doaj +2 more sources
E. coli Extracellular Matrix: A Tunable Composite With Hierarchical Structure. [PDF]
Adv MaterThe complex composite‐like mechanical behavior of E. coli biofilm matrix is the result of a synergic contribution of the rigid curli and swelling pEtN‐cellulose, and emerges from specific ratio and assembly conditions. The interactions between the two fibers govern biofilm hydration and characteristic wrinkling patterns, providing crucial insights for ...
Siri M +7 more
europepmc +2 more sources
De Novo Autogenic Engineered Living Functional Materials. [PDF]
Adv MaterA versatile platform for de novo autogenic engineered living materials is presented, leveraging protein mining, computational modeling, and synthetic biology. By reprogramming the Escherichia coli curli machinery with β‐solenoid proteins from non‐model bacteria, macroscopic biomaterials with enhanced mechanical properties, UV‐C irradiation protection ...
Hammad HM +9 more
europepmc +2 more sources
Salmonella infection and biofilms drive anti-C1q and anti-dsDNA autoantibodies in systemic autoimmunity. [PDF]
PLoS PathogensSystemic lupus erythematosus (SLE) is characterized by autoantibody production alongside inflammatory manifestations, including nephritis. In SLE, infections are frequent and associated with disease flares, increasing morbidity and mortality ...
Kaitlyn Grando +10 more
doaj +2 more sources
Effects of multiple cell regulators on curli gene expression in Escherichia coli [PDF]
Journal of BacteriologyCurli amyloid fibers are the key protenacious component of the extracellular matrix in Escherichia coli. The regulation of curli expression is highly complex and depends on multiple environmental responses.
Maryia Ratnikava +2 more
doaj +2 more sources
The Production of Curli Amyloid Fibers Is Deeply Integrated into the Biology of Escherichia coli
Biomolecules, 2017 Curli amyloid fibers are the major protein component of the extracellular matrix produced by Enterobacteriaceae during biofilm formation. Curli are required for proper biofilm development and environmental persistence by Escherichia coli.
Peter E Burby +2 more
exaly +3 more sources
Intrinsic Disorder as a New Frontier in Antimicrobial Resistance and Bacterial Fitness [PDF]
MicrobiologyopenThe works examines the link between intrinsic disorder in bacterial protein structure, and bacterial function, and antimicrobial resistance. It highlights how flexible, disordered proteins support secretion, stress responses, desiccation protection, and virulence, while also suggesting that these adaptable regions may provide novel targets for ...
O' Callaghan J +3 more
europepmc +2 more sources
Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights. [PDF]
Health Care SciThis review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Ying J +6 more
europepmc +2 more sources
PLoS Pathogens, 2022 Deposition of human amyloids is associated with complex human diseases such as Alzheimer's and Parkinson's. Amyloid proteins are also produced by bacteria.
Lauren K Nicastro +8 more
doaj +1 more source