Results 31 to 40 of about 6,556 (206)

Systemic exposure to bacterial amyloid curli alters the gut mucosal immune response and the microbiome, exacerbating Salmonella-induced arthritis

Gut Microbes, 2023
The Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection.
Shingo Bessho, Kaitlyn C. M. Grando, Kathrine Kyrylchuk, Amanda Miller, Andres J. Klein-Szanto, Wenhan Zhu, Stefania Gallucci, Vincent Tam, Çagla Tükel   +8 more
doaj   +1 more source

Wavy or curly? [PDF]

MRS Bulletin, 2022
Graphical abstract
openaire   +3 more sources

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection.

PLoS Pathogens, 2020
Reactive arthritis, an autoimmune disorder, occurs following gastrointestinal infection with invasive enteric pathogens, such as Salmonella enterica.
Amanda L Miller, J Alex Pasternak, Nicole J Medeiros, Lauren K Nicastro, Sarah A Tursi, Elizabeth G Hansen, Ryan Krochak, Akosiererem S Sokaribo, Keith D MacKenzie, Melissa B Palmer, Dakoda J Herman, Nikole L Watson, Yi Zhang, Heather L Wilson, R Paul Wilson, Aaron P White, Çagla Tükel   +16 more
doaj   +1 more source

Overexpression of Outer Membrane Protein X (OmpX) Compensates for the Effect of TolC Inactivation on Biofilm Formation and Curli Production in Extraintestinal Pathogenic Escherichia coli (ExPEC)

Frontiers in Cellular and Infection Microbiology, 2018
Our previous study showed that the inactivation of the efflux pump TolC could abolish biofilm formation and curli production of extraintestinal pathogenic Escherichia coli (ExPEC) strain PPECC42 under hyper-osmotic conditions.
Binyou Li, Qi Huang, Ailian Cui, Xueling Liu, Bo Hou, Liyuan Zhang, Mei Liu, Xianrong Meng, Shaowen Li   +8 more
doaj   +1 more source

Cell surface-localized CsgF condensate is a gatekeeper in bacterial curli subunit secretion

Nature Communications, 2023
Curli are functional amyloids present on the outer membrane of E. coli. CsgF is required for the proper assembly of curli. Here, we found that the CsgF phase separates in vitro and that the ability of CsgF variants to phase-separate is tightly correlated
Hema M. Swasthi, Joseph L. Basalla, Claire E. Dudley, Anthony G. Vecchiarelli, Matthew R. Chapman   +4 more
doaj   +1 more source

Cellulose modulates biofilm formation by counteracting curli-mediated colonization of solid surfaces in Escherichia coli

, 2008
In enterobacteria, the CsgD protein activates production of two extracellular structures: thin aggregative fimbriae (curli) and cellulose. While curli fibres promote biofilm formation and cell aggregation, the evidence for a direct role of cellulose as ...
T. Ieranò, S. Bertagnoli, de Castro, C, Landini, P, L. Tagliabue, P. Landini, C. De Castro, Gualdi, L, L. Gualdi, Bertagnoli, Stéphane, Ierano, T, Tagliabue, L   +11 more
core   +2 more sources

Shapes of a Suspended Curly Hair [PDF]

Physical Review Letters, 2014
We investigate how natural curvature affects the configuration of a thin elastic rod suspended under its own weight, as when a single strand of hair hangs under gravity. We combine precision desktop experiments, numerics, and theoretical analysis to explore the equilibrium shapes set by the coupled effects of elasticity, natural curvature, nonlinear ...
Miller, J. t., Lazarus, Arnaud, Audoly, Basile, Reis, P. m.   +3 more
openaire   +6 more sources

Curli-only FSB binding assay.

, 2018
(A) A standard curve of the FSB absorbance versus concentration was obtained in order to determine the molar absorptivity of FSB at 365 nm (ε365nm = 33.68 mM-1cm-1; r2 = 0.892).
Lynette Cegelski (816292), Courtney Reichhardt (816287)   +1 more
core   +1 more source

The biology and genetics of curly hair [PDF]

Experimental Dermatology, 2017
AbstractHair fibres show wide diversity across and within all human populations, suggesting that hair fibre form and colour have been subject to much adaptive pressure over thousands of years. All human hair fibres typically have the same basic structure.
Gillian E. Westgate, Rebecca S. Ginger, Martin R. Green   +2 more
openaire   +3 more sources

TEM images of curli.

, 2018
Untreated curli are morphologically similar to FSB treated curli. The scale bars represent 1 μm.
Lynette Cegelski (816292), Courtney Reichhardt (816287)   +1 more
core   +1 more source