Results 61 to 70 of about 724,283 (165)
Biosimilar infliximab (CT-P13) in the treatment of inflammatory bowel disease: A Norwegian observational study [PDF]
Expert Review of Gastroenterology & Hepatology, 2015 To assess the efficacy, tolerability, and safety of CT-P13 (Remsima(®)) in patients with Crohn's disease (CD) or ulcerative colitis (UC).This was a prospective observational study performed in a single center in Norway. Patients with CD (n = 46) or UC (n = 32) received CT-P13 (5 mg/kg) by intravenous infusion at weeks 0, 2, and 6.
Jørgen, Jahnsen +3 more
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.Aim Clozapine, used for treatment‐resistant schizophrenia, has a narrow therapeutic window and highly variable plasma pharmacokinetics (PK), necessitating careful monitoring. Direct measurement of unbound brain PK in humans is unethical. To develop a physiologically based pharmacokinetic–pharmacodynamic (PBPK‐PD) model to predict clozapine brain ...
Mengxu Zhang +3 more
wiley +1 more source
Efficacy of infliximab biosimilar CT-P13 induction therapy on mucosal healing in ulcerative colitis
, 2015 Introduction. CT-P13 is the first biosimilar to infliximab that was approved for the same indications as its originator infliximab in June 2014 in Hungary. No data is available on the effect of infliximab biosimilar on mucosal healing.
Nagy, Ferenc +14 more
core +1 more source
Epilepsia Open, EarlyView.Abstract Objectives Adults with developmental and epileptic encephalopathies (DEEs) often enter adult neurology care without etiologic clarification because of incomplete transition from pediatric services, outdated investigations, and attenuation of childhood electro‐clinical features over time.
Giuseppe d’Orsi +10 more
wiley +1 more source
INTRAABDOMINAL DESMOPLASTIC SMALL ROUND CELL TUMOR: CASE REPORT WITH LITERATURE REVIEW [PDF]
Euromediterranean Biomedical Journal, 2015 Intra-abdominal desmoplastic small round cell tumors are rare aggressive neoplasms, with a very poor prognosis, observed in young adults with a male predominance.
Joseph Kreiker
doaj +1 more source
Acta Psychiatrica Scandinavica, EarlyView.ABSTRACT Introduction Suicidal ideation and behaviors (SIB) are common among individuals at clinical high risk for psychosis (CHR‐P), but their relationship with the overall clinical profile remains unclear. This study aimed to identify sociodemographic/clinical factors associated with SIB in CHR‐P individuals and to examine whether subthreshold ...
Stefano Damiani +73 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Tobacco‐free nicotine pouches (NPs) are oral nicotine products promoted by manufacturers and some researchers as tools that may reduce nicotine cravings and support smoking reduction or cessation. However, evidence regarding their actual clinical impact remains limited.
Javad Heshmati +6 more
wiley +1 more source
, 2017 Copyright modification of the article: "Effectiveness and safety of CT-P13 (infliximab biosimilar) in patients with inflammatory bowel disease in real-life settings at 6 months"
Guerra Veloz, María Fernanda +8 more
core +1 more source
Design and optimisation of rapid real‐time PCR assays for the detection of key Culicoides species
Medical and Veterinary Entomology, EarlyView.Species‐specific real‐time PCR assays were designed and optimised using primer/probe sets targeting C. obsoletus, C. scoticus, C. chiopterus, C. dewulfi, C. pulicaris, C. punctatus and C. impunctatus. Primer specificity and amplification efficiency were validated through in silico specificity analysis and real‐time PCR amplification profiling.
Elsie Isiye +10 more
wiley +1 more source
Clinical and Experimental Dental Research, Volume 12, Issue 5, October 2026.ABSTRACT Objectives To delineate the craniofacial morphometric characteristics of Thai children with syndromic (SC) and non‐syndromic craniosynostosis (NSC) and to assess dental maturation relative to Chronological Age (CA). Methods This comparative cross‐sectional study evaluated 19 patients (SC: n = 13; NSC: n = 6; mean age 9.32 ± 2.67 years ...
Nutthakarn Ratanasereeprasert +7 more
wiley +1 more source