Results 71 to 80 of about 724,283 (165)

A descriptive analysis of real-world treatment patterns of innovator (Remicade®) and biosimilar infliximab in an infliximab-naïve Turkish population

Biologics: Targets & Therapy, 2018
Yusuf Yazici,1 Lin Xie,2 Adesuwa Ogbomo,2 Lorie A Ellis,3 Kavitha Goyal,4 Amanda Teeple,5 Ece A Mutlu,6 Ismail Simsek7 1Department of Internal Medicine, Division of Rheumatology, New York University Hospital for Joint Diseases, New York, NY, USA ...
Yazici Y, Xie L, Ogbomo A, Ellis LA, Goyal K, Teeple A, Mutlu EA, Simsek I   +7 more
doaj  

Exploring Lifestyle Medicine in Rheumatic and Musculoskeletal Diseases: Findings From a Modified World Café Study

Lifestyle Medicine, Volume 7, Issue 4, October 2026.
ABSTRACT Introduction Although lifestyle medicine plays a recognised role in rheumatic and musculoskeletal disease (RMD) management, understanding how it is experienced is essential for developing effective lifestyle interventions. This study aimed to explore experiences and the impact of lifestyle medicine in RMD care and identify key facilitators and
Megan Curran, Kevin Durkan, Stacey Grealis, Sean McKenna, Clodagh Toomey, Kate McCann, Norelee Kennedy, Audrey Tierney   +7 more
wiley   +1 more source

Unveiling the Uncharted Potential of 2D Materials in Li/Na–S Batteries: A Paradigm Shift From Graphene

Advanced Science, Volume 13, Issue 51, 14 September 2026.
This review explores emerging 2D materials beyond graphene, including graphdiyne, phosphorene, borophene, siloxene, MBene, antimonene, and germanene for Li/Na–S batteries. It analyzes their roles as sulfur hosts, metallic anode protectors, separators, and electrolyte fillers, emphasizing polysulfide suppression, dendrite inhibition, and interfacial ...
Naveen Kumar T. R, Xuebing Zhu, Yao‐Jie Lei, Lei Zhang, Hua Kun Liu, Weihong Lai, Guoxiu Wang, Yun‐Xiao Wang   +7 more
wiley   +1 more source

Long-Term Clinical Outcomes After Switching from Remicade((R)) to Biosimilar CT-P13 in Inflammatory Bowel Disease [PDF]

, 2017
BACKGROUND: Limited data are available on long-term clinical outcomes regarding the switch from Remicade((R)) to the infliximab biosimilar CT-P13 in inflammatory bowel disease (IBD) patients.
Hoentjen, F., Esch, A.A.J. van, Smits, L.J.T., Drenth, J.P.H., Derikx, L.A.A.P., Grelack, A., Jong, D.J. de, Boshuizen, R.S.   +7 more
core   +1 more source

Är det säkert att byta från originalläkemedlet för inflixmab, Remicade®, till CT-P13 och är CT-P13 ekvivalent med Remicade® med avseende på effekt, säkerhet, immunogenicitet och farmakokinetik?

, 2016
Biologiska läkemedel är effektiva vid flera sjukdomstillstånd men de är mycket dyra. År 2006 godkände den Europeiska läkemedelsmyndigheten försäljning av biosimilarer.
Adler, Anna
core   +3 more sources

An Optimized Diagnostic Approach for Adults With Suspected Inherited Metabolic Disorders

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
A multidisciplinary strategy that integrates deep phenotyping with expert genetic interpretation substantially increases the likelihood of reaching a diagnosis in adults suspected of having an IMD. ABSTRACT Inherited metabolic disorders (IMDs) arise from defects in metabolic pathways essential for normal biochemical function.
Machteld M. Oud, Elise A. Ferreira, Clara D. M. van Karnebeek, Robin Wijngaard, Nicole I. Wolf, Marc Engelen, Mareen Datema, Sacha Ferdinandusse, André B. P. van Kuilenburg, Laura Steinbusch, Saskia N. van der Crabben, Mirjam Langeveld, on behalf of the ZOEMBA Study Group   +12 more
wiley   +1 more source

Acute and Chronic Pancreatitis in Mitochondrial Disease: A Systematic Review

JIMD Reports, Volume 67, Issue 5, September 2026.
ABSTRACT Mitochondrial disease is a common inherited multisystem neurometabolic disorder. Pancreatic dysfunction is a recognised manifestation, most frequently presenting as mitochondrial diabetes. Although pancreatitis cases have been reported in association with mitochondrial disease, acute and chronic pancreatitis in this context remain poorly ...
Olivia Hahl, Mika H. Martikainen
wiley   +1 more source

Clinical and Genetic Analysis of Pediatric Neurodevelopmental Disorders With Complex Chromosomal Rearrangements in Two Cases

Molecular Genetics &Genomic Medicine, Volume 14, Issue 9, September 2026.
This study investigates the impact of complex chromosomal rearrangement (CCR) breakpoints on pediatric developmental delay and epilepsy. By integrating karyotype analysis with WES and/or WGS, we identified an inversion on chromosome 3 likely affecting ROBO1/DNAJC13/ACAD11 in one patient and a complex chromosome 1 rearrangement with a novel KCNA2 ...
Jiaci Li, Wenxuan Fan, Nan Liu, Shuyue Zhang, Ping Wang, Chunyu Gu, Jianbo Shu   +6 more
wiley   +1 more source

DHCR24 Alleviates DNA Damage in Senescent Vascular Endothelial Cells via ENKUR/Ca2+ Signaling

Aging Cell, Volume 25, Issue 9, September 2026.
In senescent vascular endothelial cells, DHCR24 deficiency triggers ENKUR‐dependent Ca2+ overload, which in turn induces endoplasmic reticulum stress and mitochondrial dysfunction, ultimately exacerbating oxidative stress and DNA damage. ABSTRACT DNA damage is considered one of the major contributors to aging.
Han Li, Zhen Yang, Wukaiyang Liang, Jie Huang, Tianyi Ji, Hao Nie, Zixin Wan, Yuqi Qiu, Yi Huang, Le Zhang, Cuntai Zhang, Jinhua Yan   +11 more
wiley   +1 more source

Comparable Immune Function Inhibition by the Infliximab Biosimilar CT-P13: Implications for Treatment of Inflammatory Bowel Disease

, 2017
Background and Aims: CT-P13 is the first biosimilar monoclonal antibody to infliximab, and was recently approved in the European Union, Japan, Korea, and USA for all six indications of infliximab. However, studies directly assessing the biologic activity
Choi, Eun Jin, Choi, Yong Sung, Ben-Horin, Shomron, Kim, Sunghwan, Yavzori, Miri, Lee, Eun Beom, Lee, So Jung, Jun, Hwang Keun, Cho, Jong Moon, Park, Yoon A., Jeon, Myung-Shin, Lee, Soo Young, Picard, Orit, Lim, Byung Pil, Chang, Shin Jae, Fudim, Ella, Lee, Su Yeon, Shin, Eui Cheol, Lim, Ki Jung, Kwon, Ki Sung, Lee, Min Seob   +20 more
core   +1 more source