Results 81 to 90 of about 103,919 (296)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

open access: yesAdvanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner   +8 more
wiley   +1 more source

Facile synthesis of cetyltrimethylammonium bromide-loaded mesoporous silica nanoparticles for efficient inhibition of hepatocellular carcinoma cell proliferation

open access: yesMaterials Research Express, 2020
We report the synthesis of cetyltrimethylammonium bromide (CTAB)-loaded mesoporous silica nanoparticles (MSNs) as efficient anticancer agents. The chemical composition and structure, drug loading capacity, and in vitro cytotoxicity of CTAB-MSNs were ...
Fulu Ai, Guohua Zhao, Wu Lv, Jie Lin
doaj   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

open access: yesAdvanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis   +6 more
wiley   +1 more source

Establisment of Methodology for Identification of Insect-Parasitic Fungi by Molecular Analysis on ITS1-5.8S-ITS2 Region

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2015
Insect-parastitic fungi, especially Cordyceps sinensis, parasitize larvae of insects, are used as traditional medicinal drugs in various Asian countries, including Vietnam.
Lê Huyền Ái Thúy   +5 more
doaj  

Oscillations of a solid sphere falling through a wormlike micellar fluid

open access: yes, 2002
We present an experimental study of the motion of a solid sphere falling through a wormlike micellar fluid. While smaller or lighter spheres quickly reach a terminal velocity, larger or heavier spheres are found to oscillate in the direction of their ...
A. Belmonte   +31 more
core   +1 more source

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

open access: yesAdvanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal   +9 more
wiley   +1 more source

Photothermally Powered 3D Microgels Mechanically Regulate Mesenchymal Stem Cells Under Anisotropic Force

open access: yesAdvanced Materials, EarlyView.
The photothermally powered microgel is designed to mechanically train mesenchymal stem cells using spatially patterned exogenous forces in three‐dimensional (3D) workspaces. When microgels are activated selectively via photothermal actuation, locally confined tens of nN forces are exerted on cells, triggering osteogenic differentiation in encapsulated ...
Chen Wang   +7 more
wiley   +1 more source

Recent Advances in Reactive Microdroplets for Clean Water and Energy

open access: yesAdvanced Materials, EarlyView.
Reactive microdroplets enable precise and sustainable chemistry at small scales. This review explores their role as confined reactors and dynamic interfaces for synthesizing functional materials, fuels, and microdevices. It offers a critical perspective on how droplet‐based platforms can drive next‐generation technologies in clean energy, environmental
Qiuyun Lu   +4 more
wiley   +1 more source

Differential Uptake of Gold Nanoparticles by 2 Species of Tadpole, the Wood Frog (Lithobates Sylvaticus) and the Bullfrog (Lithobates Catesbeianus)

open access: yes, 2017
Engineered nanoparticles are aquatic contaminants of emerging concern that exert ecotoxicological effects on a wide variety of organisms. We exposed cetyltrimethylammonium bromide–capped spherical gold nanoparticles to wood frog and bullfrog tadpoles ...
Andresen, Kurt   +7 more
core   +1 more source

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