Results 51 to 60 of about 281,124 (345)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

The Complex Toda Chains and the Simple Lie Algebras - Solutions and Large Time Asymptotics

, 1998
The asymptotic regimes of the N-site complex Toda chain (CTC) with fixed ends related to the classical series of simple Lie algebras are classified. It is shown that the CTC models have much richer variety of asymptotic regimes than the real Toda chain ...
Adler M, Arnold J M, Arnold J M, Bogoyavlenskii O I, Bourbaki N, Deift P, Deift P, E G Evstatiev, Farwell R, Farwell R, Flaschka H, Flaschka H, Flaschka H, Flaschka H, Gerdjikov V S, Goodman R, Goto M, Khastgir S P, Kodama Y, Kodama Y, Kodama Y, Leznov A N, Leznov A N, Leznov A N, Manakov S V, Mikhailov A V, Mikhailov A V, Moser J, Moser J, Olshanetsky M A, Olshanetsky M A, R I Ivanov, Toda M, Toda M, V S Gerdjikov   +34 more
core   +3 more sources

DNA‐Origami‐Assembled Rhodium Nanoantennas for Deep‐UV Label‐Free Single‐Protein Detection

Advanced Functional Materials, EarlyView.
Deep‐UV autofluorescence of single proteins in DNA origami‐based rhodium nanoantennas. Precisely positioned within the plasmonic nanogap, proteins retain their native state while their intrinsic emission is strongly amplified, enabling label‐free single‐molecule detection and opening new opportunities for highly sensitive and specific biosensing ...
Nicco Corduri, Malavika Kayyil Veedu, Yifan Yu, Yanqiu Zou, Jie Liu, Denis Garoli, Guillermo P. Acuna, Jérôme Wenger, Karol Kołątaj   +8 more
wiley   +1 more source

CD19 CAR-NK CONSTRUCTION WITH A NEW HINGE AND GITRL CO-EXPRESSION FOR TREG ACTIVITY INHIBITION

Hematology, Transfusion and Cell Therapy, 2023
Introduction: Chimeric Antigen Receptor T (CAR-T) cell therapy has emerged as a promising approach in which autologous T cells are engineered to recognize a specific target.
DF Schmidt, S Ebrahimabadi, MC Tirapelle, DT Covas, V Picanço-Castro   +4 more
doaj   +1 more source

How the Carrier Mobility and Seebeck Coefficient of Doped Semiconducting Polymers Are Controlled by Counterion Interactions and Mesoscale Order

Advanced Functional Materials, EarlyView.
Conventional doping of P3HT with F4TCNQ results in poor charge transport. However, when F4TCNQ is exchanged with LiTFSI, the transport characteristics are greatly enhanced. We find the increase in charge transport is directly related to an increase in the mesoscale ordering of P3HT, resulting in longer and better‐connected transport pathways.
Quynh M. Duong, Diego Garcia Vidales, Xinyu Liu, Charlene Z. Salamat, Austin Ready, Hashim Al Khunaizi, Mei Matsumoto, Alexander M. Spokoyny, Sarah H. Tolbert, Benjamin J. Schwartz   +9 more
wiley   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

Metastasis and circulating tumor cells [PDF]

, 2012
Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van, Holland, L., Terstappen, L.W.M.M.   +2 more
core   +1 more source

Closed time like curve and the energy condition in 2+1 dimensional gravity

, 1992
We consider gravity in 2+1 dimensions in presence of extended stationary sources with rotational symmetry. We prove by direct use of Einstein's equations that if i) the energy momentum tensor satisfies the weak energy condition, ii) the universe is open (
Carrol, Carrol, Carrol, Clement, Cutler, D. Seminara, Deser, Deser, Gott, Hawking, Hawking, Hooft, Kabat, Menotti, Menotti, Modanese, Ori, P. Menotti, Tipler   +18 more
core   +1 more source

Using CTCs for pharmacogenomic analysis

Pharmacological Research, 2016
In the era of precision medicine in oncology, pharmacogenomic assessment is a vital step in delivering personalized care. Increasing evidence points towards the importance of assessing molecular features of the advanced disease, rather than relying on the primary tumor sample, in order to appreciate the evolution of the tumor and to target relevant ...
Christopher D, Hart, Francesca, Galardi, Marta, Pestrin, Francesca, De Luca, Emanuela, Risi, Angelo, Di Leo   +5 more
openaire   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source