Results 51 to 60 of about 3,671 (212)

Multi‐Level Saturation Current Encoding in Two‐Dimensional Ferroelectric Source‐Gated Transistors

Advanced Functional Materials, EarlyView.
A 2D ferroelectric source‐gated transistor (SGT) operates with a non‐volatile, multi‐level saturation current controlled by ferroelectric polarization. Operando electrostatic and photocurrent imaging link the current limitation to source‐side depletion, identifying saturation current as a programmable, read‐bias‐tolerant device parameter toward low ...
Joon‐Seok Kim, Ting‐Ching Chu, Zhehao Zhu, Lincoln J. Lauhon   +3 more
wiley   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Safety and efficacy of the FAKHRAVAC compared with BBIBP-Corv2 against SARS-CoV-2 in adults: a non-inferiority multi-center trial

Virology Journal, 2023
Background We compared Fakhravac and BBIBP-Corv2 vaccines in a phase III trial. Method We conducted a multicenter, parallel-group, active-control, non-inferiority clinical trial with pragmatic considerations assessing the safety and efficacy of Fakhravac
Masoud Solaymani-Dodaran, Pouria Basiri, Milad Moradi, Kimiya Gohari, Ali Sheidaei, Mohammadreza Ahi, Farzad Ghafoori Naeeni, Akram Ansarifar, Zahra Rahimi, Fatemeh Gholami, Ahmad Karimi Rahjerdi, Ramin Hamidi Farahani, Kosar Naderi saffar, Soheil Ghasemi, Ali Shooshtari, Mohsen Honari, Ali Mozafari, Samane Khodaverdloo, Mohsen Forooghizadeh   +18 more
doaj   +1 more source

The Role of CTCs as Tumor Biomarkers

, 2015
Detection of Circulating Tumor Cells (CTCs) in peripheral blood can serve as a "liquid biopsy" approach and as a source of valuable tumor markers. CTCs are rare, and thus their detection, enumeration and molecular characterization are very challenging.
Lianidou, E.S., Markou, A., Strati, A.
openaire   +3 more sources

Electroactive 3D Porous Graphene Foam Impedimetric Biosensor for Ultrasensitive Detection of MCF‐7‐Cells‐Derived Extracellular Vesicles in Human Serum

Advanced Materials Technologies, EarlyView.
A label‐free impedimetric biosensor based on electroactive 3D porous graphene foam enables ultrasensitive and selective detection of CD81 protein and MCF‐7 cell‐derived extracellular vesicles in human serum. Detection limits of 0.048 fg/mL for CD81 and ∼24 EVs/mL are achieved, demonstrating a robust platform for selective, label‐free, and ...
Michael Robert Furness, Ashish Kalkal, Tia Wardlaw, Jessica Valli, Suresh Chandra Baral, Pablo Lozano Sanchez, Marco Caffio, Sudhagar Pitchaimuthu, Olga Oikonomidou, Jason Webber, Nick R. Leslie, Anitha Devadoss   +11 more
wiley   +1 more source

The biology and clinical potential of circulating tumor cells

Radiology and Oncology, 2019
Tumor cells can shed from the tumor, enter the circulation and travel to distant organs, where they can seed metastases. These cells are called circulating tumor cells (CTCs).
Lozar Taja, Gersak Klara, Cemazar Maja, Kuhar Cvetka Grasic, Jesenko Tanja   +4 more
doaj   +1 more source

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano, Allen C. Luo, Paul Taufalele, Jenna A. Dombroski, Ehsan Aalaei, Schyler J. Rowland, Melissa S. Cantú, Alexandria T. Carter, Samantha V. Knoblauch, Cynthia A. Reinhart‐King, Michael R. King   +10 more
wiley   +1 more source

Indium Clusters With 6s2 Lone‐Pair Effect as Excitonic Electron Reservoirs for Direct 2e− Photocatalytic H2O2 Photosynthesis

Angewandte Chemie, EarlyView.
This study demonstrates that indium clusters with 6s2 lone‐pair effect anchored on carbon nitride act as excitonic electron reservoirs to boost charge separation and O2 activation for highly selective direct 2e− oxygen reduction. This work establishes cluster‐mediated electron reservoir engineering as a general strategy for enhancing selective ...
Shijie Xie, Teng Shao, Yuye Jiao, Yurou Song, Huijie Cheng, Yaru Shao, Tianyi Ma, Jungang Hou   +7 more
wiley   +2 more sources

Imidazothiazole-based potent inhibitors of V600E-B-RAF kinase with promising anti-melanoma activity: biological and computational studies

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
A series of imidazothiazole derivatives possessing potential activity against melanoma cells were investigated for molecular mechanism of action. The target compounds were tested against V600E-B-RAF and RAF1 kinases.
Hanan S. Anbar, Mohammed I. El-Gamal, Hamadeh Tarazi, Bong S. Lee, Hong R. Jeon, Dow Kwon, Chang-Hyun Oh   +6 more
doaj   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source