Results 131 to 140 of about 24,447,859 (342)

Regional coyote densities estimated from camera trapping covary with deer productivity, anthropogenic land use, and human–coyote conflicts

Wildlife Biology, EarlyView.
Density estimates assist conservation and management decisions. Unfortunately, management of elusive mesocarnivores occurring at low densities has often relied on qualitative metrics or population indices. The proliferation of camera trap sampling of wildlife provides an opportunity to apply recently developed methods for estimating density of unmarked
Zackary J. Delisle, Audrey M. Andritsch, Robert K. Swihart, J. Andrew DeWoody   +3 more
wiley   +1 more source

Performance evaluation of large language models in answering patients' questions about treatment of connective tissue diseases

Rheumatology &Autoimmunity, EarlyView.
Chao Xue, Jiaxin Bai, Wenrui Zhang, Yiwen Wang, Yufei Guo, Jiali Yu, Jian Zhu   +6 more
wiley   +1 more source

Temporal Trends in Pregnancy Outcomes Among Parents With Type 1 Diabetes: A Nationwide Register‐Based Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To assess temporal trends in outcomes of pregnancies with maternal or paternal type 1 diabetes compared to the general population. Design Register‐based study. Setting Denmark. Population 1 551 893 pregnancies from 1997 to 2021, hereof 5478 with maternal and 8072 with paternal type 1 diabetes.
Tina Wullum Gundersen, Sine Knorr, Lene Ringholm, Dorte Moeller Jensen, Peter Damm, Karoline Kragelund Nielsen, Helena Backman, Jeannet Lauenborg, Elisabeth Reinhardt Mathiesen, Anne Helby Petersen, Niels Skipper, Allan Kofoed‐Enevoldsen, Tine Dalsgaard Clausen   +12 more
wiley   +1 more source

Early detection of interstitial lung disease in rheumatic diseases: A joint statement from the Portuguese Pulmonology Society, the Portuguese Rheumatology Society, and the Portuguese Radiology and Nuclear Medicine Society

Pulmonology
Introduction Interstitial lung disease (ILD) contributes significantly to morbidity and mortality in connective tissue disease (CTD). Early detection and accurate diagnosis are essential for informing treatment decisions and prognosis in this setting ...
A. Morais, A.C. Duarte, M.O. Fernandes, A. Borba, C. Ruano, I.D. Marques, J. Calha, J.C. Branco, J.M. Pereira, M.J. Salvador, M. Bernardes, N. Khmelinskii, P. Pinto, R. Pinto-Basto, S. Freitas, S. Campainha, T. Alfaro, A. Cordeiro   +17 more
doaj   +1 more source

The Challenges and Benefits of an Open Anterior Repair of Recurrent Inguinal Hernias: A Cohort Study

ANZ Journal of Surgery, EarlyView.
ABSTRACT Introduction Recurrent inguinal hernia repair presents unique clinical challenges. While minimally invasive surgery (MIS) is often preferred, open anterior mesh repair is a valid approach particularly when requiring mesh, suture, or tack removal. This study evaluates the outcomes of a small incision open anterior mesh repair, including foreign
Marie‐Alexandre Adom, Chun Tung D. Wu, Nazim Bhimani, Nicola Dodds, Anthony Glover, Thomas J. Hugh   +5 more
wiley   +1 more source

Defining AV2‐1 as a novel pharmacological probe to target human and rodent TRPV2

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Transient receptor potential vanilloid 2 (TRPV2) is a non‐selective cation channel implicated in immune cell functions. However, progress in understanding TRPV2 has been limited by a lack of potent and selective pharmacological tools, particularly those targeting the human variant. We aimed to identify and characterise a
Andrea Leipe, Julia A. Rocereta, Ruth A. Pumroy, Andreas Leffler, Michael Schaefer, Vera Moiseenkova‐Bell, Kerstin Hill   +6 more
wiley   +1 more source

Cantharidin: a double-edged sword in medicine and toxicology

Frontiers in Pharmacology
Cantharidin (CTD), a natural terpenoid toxin secreted by blister beetles, acts as a potent inhibitor of protein phosphatase. As the principal active component of Mylabris, a traditional Chinese medicine, CTD has attracted considerable interest due to its
Jie Zhang, Tongtong Tian, Canyu Li, Yong Liu, Yunyun Wang, Ling Liu, Liang Liu, Yufeng Yao   +7 more
doaj   +1 more source

RV Pelagia Cruise 64PE372, 27 Jun - 11 Jul 2013. Flow dynamics and sedimentation in an active submarine channel: a process-product approach [PDF]

, 2014
Novel technologies are providing new opportunities to study the structure and dynamics of submarine sediment-gravity flows; these flows are the dominant process for transfer of sediment into the deep ocean, but are very hard to monitor due their ...
et al,, Wynn, R.B.
core  

Targeting the noncatalytic activity of GSK3β modulates neuronal excitability in medium spiny neurons via Nav1.6 interactions

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kinases phosphorylate ion channels, but their noncatalytic roles via protein–protein interactions (PPI) are less understood. Here, we identified the peptidomimetic ZL141 to characterize the PPI between GSK3β and Nav1.6, revealing a noncatalytic role for GSK3β in regulating Nav1.6 currents and neuronal excitability ...
Aditya K. Singh, Zahra Haghighijoo, Akanksha Gurtu, Nolan M. Dvorak, Timothy J. Baumgartner, Nana A. Goode, Jully Singh, Matteo Bernabucci, Adam T. Szafran, Michael J. Bolt, Michael A. Mancini, Natalie M. Dvorak, Marijn Lijffijt, Zhiqing Liu, Yu Xue, Alyssa K. Thomas, Alejandro Villasante‐Tezanos, Balaji Krishnan, Jia Zhou, Fernanda Laezza   +19 more
wiley   +1 more source

An international questionnaire highlights and supports the case for including girls in Creatine Transporter Deficiency research

Frontiers in Neuroscience
Over the last 15 years, significant progress has been made for Creatine Transporter Deficiency (CTD) patients, with increased awareness and visibility, better diagnosis, and improved care.
Carole Chehowah, Carole Chehowah, Audrey Mittelman, Vincent des Portes   +3 more
doaj   +1 more source