Results 141 to 150 of about 24,447,859 (342)

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

Cell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang, Ling Rao, Xiaofang Li, Miaofen Zhang, Huiting Huang, Zhiyan Luo, Gang Liao, Yong Jiang, Shaofeng Zhan, Qiong Liu, Xiufang Huang   +10 more
wiley   +1 more source

Russian-German cooperation : the Transdrift I expedition to the Laptev Sea [PDF]

, 1994
Karpiy, V., Kassens, Heidemarie
core   +1 more source

Shipboard Techniques for Oceanographic Observations [PDF]

, 1995
This report gives the details of water sampling methods and chemical analyses used during MLML participation in the EOS MODIS investigations. It is intended to be used as a reference manual for those engaged in shipboard work.
Broenkow, William W., Feinholz, Michael, E., Flora, Stephanie J., Gashler, J. Andrew   +3 more
core  

Integrated miRNA–mRNA Analysis Reveals Obesity‐Driven Regulatory Networks in Human Visceral Adipose Tissue With and Without Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Obesity is characterised by pathological alterations in visceral white adipose tissue (vWAT) that may contribute to the development of type 2 diabetes (T2D). While microRNAs (miRNAs) are key post‐transcriptional regulators, comprehensive human vWAT profiling across metabolic states remains limited.
Elsa Villa‐Fernández, Ana Victoria García, Laura Gallardo‐Nuell, Miguel García‐Villarino, Judit Fernández‐García, Aldara Martin Alonso, Claudia Lozano‐Aida, Lorena Suárez Gutiérrez, Pedro Pujante, Jessica Ares, Tomás González‐Vidal, Raquel Rodríguez Uría, Sandra Sanz Navarro, María Moreno Gijón, Lourdes María Sanz Álvarez, Estrella Olga Turienzo Santos, José Manuel Fernández‐Real, Mario Fernández Fraga, Elías Delgado, Carmen Lambert   +19 more
wiley   +1 more source

The R203W substitution drives PACS‐1 syndrome by disrupting intramolecular regulation

The FEBS Journal, EarlyView.
The middle region (MR) of PACS‐1 controls engagement with specific partner proteins. This manuscript presents the structure of the Furin binding region (FBR) and how interactions with partners are regulated through the interplay between a basic patch in the FBR and an acidic cluster in the MR.
Troy C. Krzysiak, In‐Ja L. Byeon, Ryan Ponticelli, Mary E. Lucas, Lariah Thompson, Christopher DeHaven, Gary Thomas, Angela M. Gronenborn   +7 more
wiley   +1 more source

KU80 suppresses endonuclease G activity to preserve genomic integrity

The FEBS Journal, EarlyView.
Under normal conditions, EndoG remains restricted to mitochondria and the genome remains intact. When KU80 is absent, EndoG translocates into the nucleus, where it promotes DNA fragmentation and genomic instability. Thus, this work highlights the importance of KU80 in tightly controlling EndoG localization to preserve genome stability.
Jargalan Batsaikhan, Kwang‐Hyun Park, Hae Ryung Chang, Eunyoung Jung, Myung‐Jin Kim, Jeeyoon Kang, Hyunjo Shim, Eui‐Jeon Woo, Yonghwan Kim   +8 more
wiley   +1 more source

Decadal Rapid Change in Energetic Carrying Capacity for Juvenile Chum Salmon in the Sanriku Coast

Fisheries Oceanography, EarlyView.
ABSTRACT Adult returns to coastal rivers in Sanriku, located near the southernmost area of chum salmon distribution, have declined since 2010. Climate‐induced fluctuations in juvenile prey availability may affect growth and survival, which are linked to adult returns.
Yuki Iino, Yuichi Shimizu, Tomoki Sato, Takashi Kitagawa   +3 more
wiley   +1 more source

Environmental Drivers of Jumbo Squid During Fishery Collapse in the Gulf of California (2019–2024)

Fisheries Oceanography, EarlyView.
ABSTRACT The jumbo squid (Dosidicus gigas) is a cephalopod endemic to the eastern Pacific with significant ecological and economic importance. Its exploitation in the Gulf of California (GC) peaked in the 1990s, with catches exceeding 100,000 tons, but collapsed in 2009 and virtually disappeared by 2015, largely due to environmental changes and ...
Mario Vásquez‐Ortiz, Juan Roberto F. Vallarta‐Zárate, Jesús E. Osuna‐Soto, Emma Verónica Pérez‐Flores, Leslie Altamirano‐López, Ramón Isaac Rojas‐González   +5 more
wiley   +1 more source

The Staircase Chart: Visualising Vertical and Cross‐Shelf Movements and Dispersal of Early‐Life Fish, Applied to Japanese Jack Mackerel

Fisheries Oceanography, EarlyView.
ABSTRACT Dispersal during early life stages is a critical process shaping marine fish connectivity and population dynamics, yet direct field observations at the individual level remain elusive. This has limited our understanding of the factors controlling dispersal, including the impact of active swimming by larvae and juveniles. Here, we present a new
Tatsuya Sakamoto, Daichi Muto, Motomitsu Takahashi, Chiyuki Sassa, Toyoho Ishimura   +4 more
wiley   +1 more source

Feasibility and Outcomes of Intravenous Lithotripsy as an Adjunct in Complex Transvenous Lead Extraction

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Transvenous lead extraction (TLE) of old leads is associated with increased procedural complexity and risk due to the development of calcified vascular adhesions. This may necessitate additional tools to free the leads. Shockwave intravenous lithotripsy (IVL), which employs acoustic pressure waves to fracture calcified lesions, has ...
Mohamad Mdaihly, Joe Demian, Arshneel S. Kochar, David O. Martin, Aravinda Nanjundappa, Arwa Younis, Ali Dakik, Jaafar Ismail, Issam Motairek, Chadi Tabaja, Adele Watfa, Pasquale Santangeli, Ayman A. Hussein, Oussama M. Wazni, Thomas D. Callahan   +14 more
wiley   +1 more source