Results 181 to 190 of about 112,774 (309)

Clinical characteristics of high-altitude interstitial lung disease: a two-center, retrospective, observational study. [PDF]

BMC Pulm Med
Zhou L, Zhu M, Chen L, Wang Y, Xu L, Liu J, Chen L, Tuo Y, Meilang Q, Luo F.   +9 more
europepmc   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, Volume 20, Issue 3, Page 804-822, March 2026.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Microenvironmental niches dictate divergent fibroblast fates in reversible versus progressive lung fibrosis. [PDF]

EBioMedicine
Song L, Yang Y, Fu Y, Liu Y, Li Q, Zheng M, Yao C, Song D, Su R, Chen W, Chen J, Chen H, Xie L.   +12 more
europepmc   +1 more source

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis

ACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective To characterize clinical and transcriptomic differences in juvenile scleromyositis overlap (jOverlap) compared to juvenile systemic sclerosis (jSSc) and juvenile dermatomyositis (JDM), focusing on autoantibody profiles, organ involvement, treatment, and peripheral blood gene expression.
Amanda D. Robinson, Clare E. Pain, Gabrielle A. Morgan, Anwesha Sanyal, Srilakshmi Chaparala, Lauren M. Pachman, Kathryn S. Torok   +6 more
wiley   +1 more source

Ginsenoside RG3 and cantharidin synergistically suppress the progression of hepatocellular carcinoma via targeting the PRMT1-SREBF1 axis-mediated lipid metabolism. [PDF]

J Transl Med
Wang Y, Yuan H, Yu Y, Gou X, Wang Z, Zhou Z, Wang Z, Yan W, Wang H, Yan J.   +9 more
europepmc   +1 more source

Oceanographic results from the VERTEX 5 particle-trap experiment across the California current May-July 1984 [PDF]

, 1985
Broenkow, William W., Reaves, Richard E.
core  

Directed Functionalization of Recombinant Spider Silk Nonwoven Membranes with Antibodies Using Non‐Canonical Amino Acids

Advanced Materials, Volume 38, Issue 14, 6 March 2026.
A recombinant spider silk protein was functionalized by incorporating genetically encoded bio‐orthogonal reactive azido‐groups. The azido‐functionalized proteins were produced in a scalable biotechnological process, and particles, films, as well as nanofibers were established as anchorage for fully functional antibodies via site‐specific bio‐orthogonal
Claudia Lacombe, Charlotte Leonhardt, Martin Humenik, Birgit Wiltschi, Thomas Scheibel   +4 more
wiley   +1 more source

Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction. [PDF]

PLoS One
Hu Y, Hu H, Xu L, Tang X, Wang C, Lian Z, Xie C, Xie Z, Wang Q.   +8 more
europepmc   +1 more source

CARING 2022. CTD-O2 data report

This cruise is a merger of two projects: FIGURE (Fine scales shaping nitrogen fIxation in the GUlf stream) about the biological topic and CARING (CARbon Irrigation to the North-atlantic by the Gulf stream) about physical study. We report here a focus on the acquisition and calibration steps of the physical variables measured during the CARING profiles ...
Le Bihan, Caroline, Carracedo, Lidia
openaire   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen, Xin Wang, Haifeng Ding, Bosheng Zheng, Keni Zeng, Chuying Hu, Jiayi Liu, Xiao Zhu, Haibing Yu   +8 more
wiley   +1 more source