Results 11 to 20 of about 112,774 (309)

The non-canonical CTD of RNAP-II is essential for productive RNA synthesis in Trypanosoma brucei. [PDF]

open access: yesPLoS ONE, 2009
The carboxy-terminal domain (CTD) of the largest subunit (RPB1) of RNA polymerase II (RNAP-II) is essential for gene expression in metazoa and yeast. The canonical CTD is characterized by heptapeptide repeats.
Anish Das, Vivian Bellofatto
doaj   +1 more source

Referencing geostrophic velocities using ADCP data Referencing geostrophic velocities using ADCP data

open access: yesScientia Marina, 2010
Acoustic Doppler Current Profilers (ADCPs) have proven to be a useful oceanographic tool in the study of ocean dynamics. Data from D279, a transatlantic hydrographic cruise carried out in spring 2004 along 24.5°N, were processed, and lowered ADCP (LADCP)
Isis Comas-Rodríguez   +2 more
doaj   +1 more source

Isolated positive anti-SS-B autoantibodies are not related to clinical features of systemic autoimmune diseases: Results from a routine population survey. [PDF]

open access: yesPLoS ONE, 2017
To assess in clinical practice the frequency and diagnosis associated with the SS-B-positive/SS-A negative autoantibody profile.We analyzed a one-year consecutive population of 624 patients referred by clinicians to the immunology laboratory to ...
Sabine Jardel   +13 more
doaj   +1 more source

Interstitial pneumonia with autoimmune features: monocentric prospective study

open access: yesТерапевтический архив, 2023
Aim. To study demographic, clinical, serological and morphological features of interstitial pneumonia with autoimmune features (IPAF), compare survival in IPAF and interstitial lung disease in connective tissue diseases (CTD-ILD), and identify predictors
Larisa A. Akulkina   +5 more
doaj   +1 more source

LncRNA CTD-3252C9.4 modulates pancreatic cancer cell survival and apoptosis through regulating IFI6 transcription

open access: yesCancer Cell International, 2021
Background Pancreatic cancer (PC) is one of the most lethal cancer types with high degree of malignancy and poor prognosis. Recent studies have shown that long non-coding RNAs (lncRNAs) were associated with the initiation and progression of pancreatic ...
Xin Yin   +8 more
doaj   +1 more source

CTD: Fast, accurate, and interpretable method for static and dynamic tensor decompositions. [PDF]

open access: yesPLoS ONE, 2018
How can we find patterns and anomalies in a tensor, i.e., multi-dimensional array, in an efficient and directly interpretable way? How can we do this in an online environment, where a new tensor arrives at each time step?
Jungwoo Lee, Dongjin Choi, Lee Sael
doaj   +1 more source

High-affinity anti-Arc nanobodies provide tools for structural and functional studies

open access: yesPLoS ONE, 2022
Activity-regulated cytoskeleton-associated protein (Arc) is a multidomain protein of retroviral origin with a vital role in the regulation of synaptic plasticity and memory formation in mammals.
Sigurbjörn Markússon   +9 more
doaj   +3 more sources

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

INTERSTITIAL PULMONARY FIBROSIS ASSOCIATED CONNECTIVE TISSUE DISEASES – CLINICAL AND IMAGING ASPECTS [PDF]

open access: yesRomanian Journal of Rheumatology, 2017
The lung is a common site of complications in systemic connective tissue diseases (CTD), and its involvement can present in several ways. Although it is generally thought that interstitial lung disease develops later on in CTD, it is often the initial ...
Madalina Gheorghe   +2 more
doaj   +1 more source

Up-regulation of CTD-2547G23.4 in hepatocellular carcinoma tissues and its prospective molecular regulatory mechanism: a novel qRT-PCR and bioinformatics analysis study

open access: yesCancer Cell International, 2018
Background Dysregulated expression of long non-coding RNAs (lncRNAs) has been reported in the pathogenesis and progression of multiple cancers, including hepatocellular carcinoma (HCC). LncRNA CTD-2547G23.4 is a novel lncRNA, and its role in HCC is still
Dong-yue Wen   +7 more
doaj   +1 more source

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