Results 211 to 220 of about 24,447,859 (342)

Noonan Syndrome Spectrum Disorders Predispose to Systemic Lupus Erythematosus: Case Report and Critical Review of the Literature

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1091-1097, May 2026.
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou   +6 more
wiley   +1 more source

Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley   +1 more source

Advancing clinical insight into creatine transporter deficiency: long term outcome and new observations from the Italian cohort. [PDF]

open access: yesOrphanet J Rare Dis
Alessandrì MG   +9 more
europepmc   +1 more source

Phase Separation of Parkinson's Disease Protein α‐Synuclein: Mechanistic Insights but Biological Uncertainties

open access: yesChemistryEurope, Volume 4, Issue 5, May 2026.
Parkinson's disease‐associated protein α‐synuclein can assemble into liquid condensates under strongly perturbed in vitro and in vivo experimental conditions, including high protein concentration, macromolecular crowding, and when attached to various tags with cross‐linking ability.
Simran Arora   +1 more
wiley   +1 more source

Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI. [PDF]

open access: yesProc Natl Acad Sci U S A
Barmada MI   +8 more
europepmc   +1 more source

Experimental methods in chemical engineering: Atomic absorption spectrometry—AAS

open access: yesThe Canadian Journal of Chemical Engineering, Volume 104, Issue 5, Page 2206-2224, May 2026.
Abstract Elements absorb electromagnetic radiation (light) of a specific wavelength in proportion to the number of atoms in its path. As the atoms absorb this light energy, electrons rise from the ground state to an excited state. In atomic absorption spectrometry (AAS), high temperatures produce clouds of atoms from the sample (atomization) and ...
Emily Cintia Tossi de A. Costa   +4 more
wiley   +1 more source

Enhanced Bioactivity of Puerariae Radix‐ Hovenia Seed Extracts Through Lactiplantibacillus plantarum and Lacticaseibacillus paracasei Co‐Fermentation: Impact on Alcoholic Liver Injury and Macrophage Polarization

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy