Results 211 to 220 of about 24,447,859 (342)
ABSTRACT RASopathies are clinically overlapping neurodevelopmental syndromes resulting from germline mutations in genes involved in the rat sarcoma/mitogen‐activated protein kinases (RAS/MAPK) pathway. Historically, RASopathies have been described by clinical phenotypes, such as Noonan syndrome and Neurofibromatosis type I.
Anastasia‐Vasiliki Madenidou +6 more
wiley +1 more source
Aptamer-Mediated Dual-Loaded Liposomal Nanosystem for Synergistic Therapy in Hepatocellular Carcinoma via mTOR/HIF-1α/VEGF Pathway. [PDF]
Wei A +6 more
europepmc +1 more source
Contemporary Applications of Chemical Libraries for Drug Discovery and Methods for Their Synthesis
Screening of chemical libraries has over the past decades become a cornerstone of drug discovery. Today, a broad range of chemical libraries exist but they are often not well described in terms of diversity. This review describes current efforts which aim to visualize chemical diversity in compound collections and discuss current trends in synthetic ...
Tobias N. Hansen, Nils J. V. Hansen
wiley +1 more source
Advancing clinical insight into creatine transporter deficiency: long term outcome and new observations from the Italian cohort. [PDF]
Alessandrì MG +9 more
europepmc +1 more source
Parkinson's disease‐associated protein α‐synuclein can assemble into liquid condensates under strongly perturbed in vitro and in vivo experimental conditions, including high protein concentration, macromolecular crowding, and when attached to various tags with cross‐linking ability.
Simran Arora +1 more
wiley +1 more source
Mechanism of 30S subunit recognition and modification by the conserved bacterial ribosomal RNA methyltransferase RsmI. [PDF]
Barmada MI +8 more
europepmc +1 more source
Experimental methods in chemical engineering: Atomic absorption spectrometry—AAS
Abstract Elements absorb electromagnetic radiation (light) of a specific wavelength in proportion to the number of atoms in its path. As the atoms absorb this light energy, electrons rise from the ground state to an excited state. In atomic absorption spectrometry (AAS), high temperatures produce clouds of atoms from the sample (atomization) and ...
Emily Cintia Tossi de A. Costa +4 more
wiley +1 more source
A Cold World: Pain Outcomes and Patient Experiences Utilizing an Iceless Cold Compression System After Hand Surgery. [PDF]
Zeng F +4 more
europepmc +1 more source
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun +7 more
wiley +1 more source

