Successful Treatment of Immune Checkpoint Inhibitor-Induced Myocarditis, Myositis, and Myasthenia Overlap Syndrome With Baricitinib and Abatacept. [PDF]
Alnahas Z +3 more
europepmc +1 more source
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is frequently diagnosed at advanced stages and has historically been associated with poor outcomes. Immune checkpoint inhibition has transformed the therapeutic landscape, offering durable responses in recurrent, metastatic, and locally advanced disease.
Carol R. Bradford +5 more
wiley +1 more source
Immune checkpoint inhibitors in medulloblastoma: current updates in preclinical and clinical developments. [PDF]
Welch RL, Moziak K, Zang X, Martin AM.
europepmc +1 more source
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley +1 more source
Immune Checkpoint-Based Therapies in Colorectal Cancer-Current Approaches and Future Perspectives. [PDF]
Nakielska K, Plewka J, Lenart M.
europepmc +1 more source
Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait +5 more
wiley +1 more source
Phenotypic, functional, prognostic and predictive significance of B-cell and antibody responses in human melanoma: a scoping review. [PDF]
Booth L +15 more
europepmc +1 more source
Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang +11 more
wiley +1 more source
Our study enrolled 10 septic shock patients with immunosuppression and 10 healthy controls and sorted CD8+ and CD4+ T cells for transcriptome sequencing. Disease‐specific cell types, key transcripts, and TCR features were identified using integrated analysis.
Yawen Xie +6 more
wiley +1 more source
Targeting regulatory T cells in the prostate cancer microenvironment: From mechanisms to therapeutics (Review). [PDF]
Luo H.
europepmc +1 more source

