Results 161 to 170 of about 69,132 (251)

Immunotherapeutic Approaches to Head and Neck Squamous Cell Carcinoma: Current Clinical Practice and Future Directions

open access: yesHead &Neck, Volume 48, Issue 9, Page 2584-2592, September 2026.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is frequently diagnosed at advanced stages and has historically been associated with poor outcomes. Immune checkpoint inhibition has transformed the therapeutic landscape, offering durable responses in recurrent, metastatic, and locally advanced disease.
Carol R. Bradford   +5 more
wiley   +1 more source

Nanomaterial‐Mediated Radiotherapy–Immunotherapy Combinations: Breaking Immunosuppression and Revolutionizing Cancer Treatment

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Nanomaterials integrate radiotherapy and immunotherapy by enhancing radiosensitivity, remodeling the immunosuppressive tumor microenvironment, and promoting systemic antitumor immunity. This review summarizes the latest strategies of nanomaterial‐mediated combinations (RT, immunotherapy, IRT) and highlights future directions for overcoming clinical ...
Peijie Li, Xiangqin Wang, Sisi He, Hu Ma
wiley   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait   +5 more
wiley   +1 more source

Phenotypic, functional, prognostic and predictive significance of B-cell and antibody responses in human melanoma: a scoping review. [PDF]

open access: yesBr J Dermatol
Booth L   +15 more
europepmc   +1 more source

Oral lichenoid lesions in CTLA‐4 haploinsufficiency: Targeting IFN‐γ‐driven mucosal immunopathology

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Chen Wang   +11 more
wiley   +1 more source

Restricted TCR Diversity and Expansion of CD177+CD8+ and TLR4+CD4+T Cell Subsets in Septic Shock‐Associated Immunosuppression: A Single‐Cell Multi‐Omics Study

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Our study enrolled 10 septic shock patients with immunosuppression and 10 healthy controls and sorted CD8+ and CD4+ T cells for transcriptome sequencing. Disease‐specific cell types, key transcripts, and TCR features were identified using integrated analysis.
Yawen Xie   +6 more
wiley   +1 more source

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