Results 171 to 180 of about 69,132 (251)

Cytotoxic T lymphocyte antigen-4 (CTLA-4) als therapeutisches Target in der Tumorimmuntherapie [PDF]

Arzneimittelforschung, 2012
openaire   +1 more source

Abscopal Effect in Radiation Therapy: The Immune Mechanisms and Clinical Advances

MedComm, Volume 7, Issue 9, September 2026.
The schematic outlines the key events of the abscopal effect. (Ignition) Local radiotherapy (RT) induces the release of immunogenic signals from the tumor, leading to dendritic cell (DC) activation. (Orchestration) In the tumor‐draining lymph node (TDLN), DCs prime naive T cells into cytotoxic T lymphocytes (CTLs), a process modulated by regulatory T ...
Yihong Dong, Moran Chen, Xupeng Hou, Xiaoya Tang, Xiaoli Yu, Jing Liu   +5 more
wiley   +1 more source

Umbrella Systematic Review of the Efficacy and Safety of PD-1 Inhibitors Combined with CTLA-4 Inhibitors in the Treatment of Melanoma. [PDF]

Int J Mol Sci
Zhou Z, Zhu C, Yang Q, Ji C, Ma L, Wang F.   +5 more
europepmc   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Immunotherapy innovations in triple-negative breast cancer: targeting checkpoints, combinations, and biomarkers. [PDF]

Oncol Rev
Wang ZX, Chu JH, Wang YR, Huang LY, Qian MP.   +4 more
europepmc   +1 more source

Cancer heterogeneity explored through immune cell deconvolution of the tumor microenvironment

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Cancer is a highly heterogeneous disease, characterized by significant variability across multiple dimensions. This diversity has been extensively studied from various perspectives. In this study, we aim to examine cancer heterogeneity through the lens of immune cell composition within the tumor microenvironment.
Limin Jiang, Chung‐I Li, Rui Xin, Jijun Tang, Yan Guo   +4 more
wiley   +1 more source

T-cell exhaustion in tumor immunology: mechanisms, heterogeneity, and therapeutic strategies. [PDF]

Front Immunol
Wang R, Guo Y.
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

Cervical Cytokine Profile in High‐Grade Squamous Intraepithelial Lesions

Cytopathology, Volume 37, Issue 5, Page 523-530, September 2026.
Hypothetical mechanism of immune modulation in HSIL associated with high‐risk HPV infection, based on observed cytokine suppression. The diagram illustrates impaired Th1 responses, reflected by reduced production of IL‐2 and TNF, which may compromise the activation and cytotoxic function of CD8+ T cells and NK cells, facilitating immune evasion.
Talles Henrique de Araújo Pontes, Amaxsell Thiago Barros de Souza, Carolina de O. Mendes‐Aguiar, Maria do Perpétuo Socorro Nobre Medeiros e Silva, Juliana Dantas de Araújo Santos Camargo, George Alexandre Lira, Ricardo Ney Cobucci, Deyse de Souza Dantas, Janaina Cristiana de Oliveira Crispim   +8 more
wiley   +1 more source

Circulating cell populations as response predictors and targets to improve immunotherapy in metastatic lung cancer. [PDF]

iScience
Figueiredo AB, Evangelista GFB, Ferreira SMI, Kuil LM, Barbeta G, Iohan LC, Faccio AT, Cardozo KHM, Carvalho VM, Cavalcanti CM, Balderas R, Lopes RP, Turner J, Souza-Silva TG, Silva JCS, Avila JP, Nakaya HTI, Galdino NAL, Lopes AD, Morais KLP, Santos IP, Freitas HC, Gross JL, Pinto CAL, Chojniak R, Dutra WO, Cordeiro-de-Lima VC, Gollob KJ.   +27 more
europepmc   +1 more source