Results 41 to 50 of about 1,591 (146)
Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI
iNew Medicine, EarlyView.Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang +9 more
wiley +1 more source
Porous Organic Polymers: From Molecular Design to Scalable Technologies
Small, EarlyView.This review introduces porous organic polymers (POPs) for a wide range of applications, including energy storage, gas adsorption, catalysts, adsorbents, biomedical applications, sensors, and other exciting fields, and critically analyzes the synthesis and modification, and how structural topology influences the composites' architecture of POPs, along ...
Hossein Mashhadimoslem +12 more
wiley +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo +2 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 8, August 2026.ABSTRACT Roads are a major source of landscape fragmentation that can influence movement patterns, survival, and behavioral states of carnivore species. Understanding their behavior and response to roads is crucial for developing effective mitigation strategies such as wildlife crossing structures, exclusion fencing, and habitat connectivity planning ...
Rupesh Maharjan +8 more
wiley +1 more source
MedComm, Volume 7, Issue 8, August 2026.Inflammation in cardiovascular disease is a dynamic and context‐dependent network rather than a secondary response to injury. Mitochondrial danger signaling links metabolic stress to immune activation through TLR priming, NLRP3 inflammasome amplification, cGAS–STING signaling, and immunometabolic gating, providing a basis for more precise therapeutic ...
Jiaxiang Rong +8 more
wiley +1 more source
A G339R mutation in the CTNS gene is a common cause of nephropathic cystinosis in the south western Ontario Amish Mennonite population [PDF]
Journal of Medical Genetics, 2001 Editor—Nephropathic cystinosis (MIM 219800) is a rare autosomal recessively inherited lysosomal storage disorder with a newborn incidence of about 1 in 100 000-200 000 in the general population (OMIM). Cystine accumulates in lysosomes because of dysfunctional cystinosin mediated transport of cystine out of lysosomes. The accumulation of cystine results
C A, Rupar, D, Matsell, S, Surry, V, Siu
openaire +2 more sources
Advanced Biomedical ResearchBackground: Nephropathic cystinosis (NC) is an uncommon autosomal recessive disease with abnormality in lysosomal storage that appearances in patients with mutations in the CTNS gene encoding a lysosomal transporter cystinosin. Disrupted function of this
Zahra Mohammadi Chermahini +5 more
doaj +1 more source
Frontiers in Endocrinology, 2019 Cystinosis is a lysosomal storage disorder caused by defects in CTNS, the gene that encodes the lysosomal cystine transporter cystinosin. Patients with nephropathic cystinosis are characterized by endocrine defects, defective proximal tubule cell (PTC ...
Jinzhong Zhang +6 more
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Perspective of the European Cystic Fibrosis Society on Improving Global Cystic Fibrosis Care
Pediatric Pulmonology, Volume 61, Issue 7, July 2026.ABSTRACT Introduction Outcomes for people with the inherited disease, cystic fibrosis, have improved greatly over the last few decades, but one result of this is a widening gap between regions with high income and well‐resourced healthcare systems and low/middle income countries.
Jane C. Davies +7 more
wiley +1 more source
Pigment Cell &Melanoma Research, Volume 39, Issue 4, July 2026.HO‐1 acts as a context‐dependent regulator of pigmentation, enhancing tyrosinase activity and melanin accumulation in melanoma cells while having no detectable effect on pigmentation in the non‐malignant melanocyte models tested. ABSTRACT Melanogenesis is a defining feature of melanocyte biology and influences melanoma pathogenesis; however, tumor ...
Agnieszka Seretny +13 more
wiley +1 more source