Results 61 to 70 of about 1,591 (146)

Inflammation, Immunity, and Cardiovascular Diseases

Med Research, Volume 2, Issue 2, Page 343-370, June 2026.
Cardiovascular stress signals (e.g., hemodynamic shear, oxidized lipids, and ischemia) act on endothelial and immune cells to activate and amplify inflammation through NF‐κB, the NLRP3 inflammasome, and JAK/STAT signaling, inducing proinflammatory cytokines/chemokines (IL‐6, IL‐1β, TNF‐α, and CCL2) and self‐amplifying circuits; clinically, inflammatory
Dezhi Guo, Yan Liao, Rui Zhao, Zhaoyu Li, Kaikai Wang, Haoling Zhang, Pingxin Sun, Yadong Guo, Wangzheqi Zhang   +8 more
wiley   +1 more source

Chromosomal Mapping of HumanarmadilloGenes Belonging to the p120ctn/Plakophilin Subfamily

Genomics, 1998
Armadillo-like proteins are characterized by a series of armadillo repeats that are typically 42 to 45 amino acids in length. Three major subfamilies of Armadillo-like proteins can be distinguished on the basis of their number of repeats, their overall sequence similarity, and dispersion of the repeats throughout the protein.
Bonne, Stefan, Van Hengel, Jolanda, Van Roy, F.   +2 more
openaire   +3 more sources

Nephropathic Cystinosis: Symptoms, Treatment, and Perspectives of a Systemic Disease

Frontiers in Pediatrics, 2018
Cystinosis is a rare autosomal recessive lysosomal storage disorder caused by mutations in the CTNS gene. Main dysfunction is a defective clearance of cystine from lysosomes that leads to accumulation of cystine crystals in every tissue of the body ...
Sören Bäumner, Lutz T. Weber
doaj   +1 more source

Don't Cut the Cord: Why Umbilical Cord Blood Still Deserves a Place in Transplantation

International Journal of Immunogenetics, Volume 53, Issue 3, Page 229-239, June 2026.
ABSTRACT The use of umbilical cord blood (UCB) as a stem cell source in haematopoietic stem cell transplant (HSCT) has greatly declined in recent years. It has largely been replaced by mismatched unrelated and family donors, facilitated by advances in transplant technologies, including post‐transplant cyclophosphamide to prevent graft‐versus‐host ...
Jenna Nunn, Kay Poulton, Robert Wynn
wiley   +1 more source

Recent Advances in the Synthesis and Processing of Carbon Nanotubes and Carbon Nanocomposites for Energy Storage, Biomedical, and Environmental Applications

ChemistryOpen, Volume 15, Issue 5, May 2026.
This review summarizes recent advances in the synthesis and processing of carbon nanotubes and carbon nanocomposites, highlighting structure–property relationships and their applications in energy storage, biomedical systems, and environmental technologies, with emphasis on performance optimization and sustainable material design.
Noor‐ul‐Huda Altaf, Muhammad Ayyaz, Yaning Zhang, Mudassar Shahzad, Ayesha Khan, Sanam, Wasqa Liaqat, Ambreen Ashar, Roshaan Malik, Zeeshan Ahmad Bhutta   +9 more
wiley   +1 more source

Follow‐Up of Children With Primary Ciliary Dyskinesia

Pediatric Pulmonology, Volume 61, Issue 5, May 2026.
ABSTRACT Primary ciliary dyskinesia (PCD) is a genetically heterogeneous disorder resulting in defective ciliary motility, which leads to a spectrum of clinical manifestations, including chronic upper and lower respiratory infections, middle ear disease, situs abnormalities, congenital heart defects, and infertility.
Bruna Rubbo, Jonathan Wen Yi Ong, William Tsang, Lydia M. Newman, Jane S. Lucas   +4 more
wiley   +1 more source

G‐CSF for Mobilizing CD34+ Cells in Individuals With SCD: A Word of Caution

American Journal of Hematology, Volume 101, Issue 6, Page 1178-1181, June 2026.
Akshay Sharma, Allistair Abraham, Monica Bhatia, María Cancio, Sonali Chaudhury, Selim Corbacioglu, Gregory M. T. Guilcher, Ashish O. Gupta, Rabi Hanna, Matthew M. Heeney, Tami John, Lakshmanan Krishnamurti, James L. LaBelle, Hemalatha G. Rangarajan, Shalini Shenoy, Elizabeth Stenger, Crawford Strunk, Courtney D. Fitzhugh   +17 more
wiley   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Application of next generation sequencing in genetic counseling a case of a couple at risk of cystinosis

BMC Medical Genetics, 2020
Background In Morocco, consanguinity rate is very high; which lead to an increase in the birth prevalence of infants with autosomal recessive disorders. Previously, it was difficult to diagnose rare autosomal recessive diseases.
Mouna Ouhenach, Abdelali Zrhidri, Imane Cherkaoui Jaouad, Wiam Smaili, Abdelaziz Sefiani   +4 more
doaj   +1 more source

Diagnostic challenge in a patient with nephropathic juvenile cystinosis: a case report

BMC Nephrology, 2017
Background Cystinosis is a rare autosomal recessive lysosomal disorder characterized by the accumulation of cystine in lysosomes. Cystinosis is much rarer in Asian than Caucasian populations. There are only 14 patients have with cystinosis alive in Japan.
Satomi Higashi, Natsuki Matsunoshita, Masako Otani, Etsuro Tokuhiro, Kandai Nozu, Shuichi Ito   +5 more
doaj   +1 more source