Results 11 to 20 of about 48,872 (261)
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Pilot and Feasibility Studies, 2020 Background Huntington’s disease (HD) is associated with a range of cognitive deficits including problems with executive function. In the absence of a disease modifying treatment, cognitive training has been proposed as a means of slowing cognitive ...
Emma Yhnell +9 more
doaj +1 more source
Dynamic Parameterized Network for CTR Prediction
CoRR, 2021 Learning to capture feature relations effectively and efficiently is essential in click-through rate (CTR) prediction of modern recommendation systems. Most existing CTR prediction methods model such relations either through tedious manually-designed low-order interactions or through inflexible and inefficient high-order interactions, which both ...
Jian Zhu +8 more
openaire +2 more sources
BMC Musculoskeletal Disorders, 2017 Background Denosumab treatment for up to 8 years in the FREEDOM study and Extension was associated with low fracture incidence. It was not clear whether subjects who discontinued during the study conduct had a higher risk of fracture than those who ...
Jonathan D. Adachi +11 more
doaj +1 more source
CDK12 Activity-Dependent Phosphorylation Events in Human Cells
Biomolecules, 2019 We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12analog-sensitive HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in human ...
Bartlomiej Bartkowiak +3 more
doaj +1 more source
Brain Sciences, 2020 Chronic disorders of consciousness cause a total or partial and fluctuating unawareness of the surrounding environment. Virtual reality (VR) can be useful as a diagnostic and/or a neurorehabilitation tool, and its effects can be monitored by means of ...
Maria Grazia Maggio +8 more
doaj +1 more source
Analysis of the sensitivity to pressure and temperature of a membrane based SAW sensor
International Journal of Smart and Nano Materials, 2017 This paper presents a FEM analysis of a membrane-based Surface Acoustic Wave (SAW) sensor. The sensor is a 2.45GHz Reflective Delay Line (R-DL) based on Lithium Niobate (LiNbO3). As the wave propagation time is much smaller than the typical time constant
Hugo Chambon +3 more
doaj +1 more source
A General Framework for Debiasing in CTR Prediction
CoRR, 2021 Most of the existing methods for debaising in click-through rate (CTR) prediction depend on an oversimplified assumption, i.e., the click probability is the product of observation probability and relevance probability. However, since there is a complicated interplay between these two probabilities, these methods cannot be applied to other scenarios, e ...
Wenjie Chu +5 more
openaire +2 more sources
Claisen thermally rearranged (CTR) polymers [PDF]
Science Advances, 2016 Second generation of thermally rearranged polymers presents low temperatures for a complete rearrangement.
Alberto Tena +4 more
openaire +3 more sources
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source