Results 21 to 30 of about 49,499 (264)

A General Framework for Debiasing in CTR Prediction

open access: yesCoRR, 2021
Most of the existing methods for debaising in click-through rate (CTR) prediction depend on an oversimplified assumption, i.e., the click probability is the product of observation probability and relevance probability. However, since there is a complicated interplay between these two probabilities, these methods cannot be applied to other scenarios, e ...
Wenjie Chu   +5 more
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Exploring computerised cognitive training as a therapeutic intervention for people with Huntington’s disease (CogTrainHD): protocol for a randomised feasibility study

open access: yesPilot and Feasibility Studies, 2018
Background Cognitive impairments, especially deficits of executive function, have been well documented as a core and early feature in Huntington’s disease (HD).
Emma Yhnell   +9 more
doaj   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

Visual Encoding and Debiasing for CTR Prediction

open access: yesProceedings of the 31st ACM International Conference on Information & Knowledge Management, 2022
Extracting expressive visual features is crucial for accurate Click-Through-Rate (CTR) prediction in visual search advertising systems. Current commercial systems use off-the-shelf visual encoders to facilitate fast online service. However, the extracted visual features are coarse-grained and/or biased.
Guipeng Xv   +8 more
openaire   +3 more sources

Multilayered, Package-Less SAW Sensors: Latest Developments

open access: yesProceedings, 2018
Passive and wireless SAW sensors can operate in extreme environment. However, there is no mass-market application for this technology yet, due notably to the lack of an adequate sensor housing solution.
Pascal Nicolay   +2 more
doaj   +1 more source

From Rigid to Soft Robotic Approaches for Neuroendoscopy

open access: yesAdvanced Robotics Research, EarlyView.
Robotic assistance has had minimal impact on deep intraventricular surgeries, where small‐scale, precision, and reduced invasiveness can contribute to improved patient outcomes. Emerging technologies in rigid, soft, and hybrid robotics are reviewed to identify the most promising mechanisms for deep brain navigation in addition to an attempt to identify
Kieran Gilday   +3 more
wiley   +1 more source

Livsvarigt fængsel ctr. psykopatforvaring

open access: yesNordisk Tidsskrift for Kriminalvidenskab, 1972
See abstract in article.
Sv. Gram Jensen
doaj   +1 more source

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin   +15 more
wiley   +1 more source

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