Results 41 to 50 of about 71,036 (261)

Characterization of CTX-M-14 and CTX-M-15 producing Escherichia coli strains causing neonatal sepsis [PDF]

, 2017
Neonatal sepsis is a disease affecting newborns ≤1 month of age with clinical symptoms and positive blood cultures. The number of Escherichia coli strains causing neonatal sepsis resistant to the antibiotics used in the treatment is increasing.
Bosch Mestres, Jordi, Guiral Vilalta, Elisabet, López, Yuly, Montero, Ignacio, Soto González, Sara M., Sáez-López, Emma, Vila Estapé, Jordi   +6 more
core   +1 more source

Effect of spacer sequences between bla CTX-M and ISEcp1 on bla CTX-M expression

Journal of Medical Microbiology, 2011
Spacer sequences of 42 and 127 bp, respectively, between the ISEcp1 insertion sequence and bla(CTX-M) have been observed in Klebsiella pneumoniae. However, it is not known whether different spacers upstream of bla(CTX-M) and a promoter within the 127 bp spacer influence cephalosporin resistance.
Ling, Ma, Leung Kris, Siu, Po-Liang, Lu
openaire   +2 more sources

The Novel CTX-M-116 β-Lactamase Gene Discovered in Proteus mirabilis Is Composed of Parts of the CTX-M-22 and CTX-M-23 Genes [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACTThe novel β-lactamase geneblaCTX-M-116was identified in aProteus mirabilisnosocomial isolate recovered from the urine of a patient in Moscow in 2005. DNA sequence analysis showedblaCTX-M-116to be a hybrid gene consisting of 5′blaCTX-M-23(nucleotides 1 to 278) and 3′blaCTX-M-22(nucleotides 286 to 876) moieties separated by an intervening ...
N, Fursova, S, Pryamchuk, A, Kruglov, I, Abaev, E, Pecherskikh, N, Kartsev, E, Svetoch, I, Dyatlov   +7 more
openaire   +2 more sources

Structural Comparisons of Cefotaximase (CTX-M-ase) Sub Family 1

Frontiers in Microbiology, 2021
The cefotaximase or CTX-M, family of serine-β-lactamases represents a significant clinical concern due to the ability for these enzymes to confer resistance to a broad array of β-lactam antibiotics an inhibitors.
Ben A. Shurina, Richard C. Page, Richard C. Page   +2 more
doaj   +1 more source

Interaction of carbapenems and β-lactamase inhibitors towards CTX-M-15 and CTX-M-15 G238C mutant

Journal of Global Antimicrobial Resistance, 2017
The aim of this study was to evaluate the role of residue 238 in CTX-M-15 and CTX-M-15G238C mutant with respect to carbapenems and various β-lactamase inhibitors.A CTX-M-15G238C laboratory mutant was generated by site-directed mutagenesis from CTX-M-15 enzyme by replacing glycine 238 with cysteine.
Sabatini, Alessia, Brisdelli, Fabrizia, Celenza, Giuseppe, Marcoccia, Francesca, Colapietro, Martina, Tavío Pérez, María del Mar, Piccirilli, Alessandra, Amicosante, Gianfranco, Perilli, Mariagrazia   +8 more
openaire   +3 more sources

Prevalence and characteristics of extended spectrum β-lactamase-producing Escherichia coli from bovine mastitis cases in China

Journal of Integrative Agriculture, 2018
The aim of the study was to investigate the prevalence and characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli isolated from bovine mastitis cases in China. ChromID ESBL agar was used to confirm ESBL-producing E. coli. PCR
Feng YANG, Shi-dong ZHANG, Xiao-fei SHANG, Xu-rong WANG, Ling WANG, Zuo-ting YAN, Hong-sheng LI   +6 more
doaj   +1 more source

Primer relevamiento de marcadores de resistencia a antibióticos en Enterobacteriaceae en Cochabamba, Bolivia [PDF]

, 2017
Se llevó a cabo un relevamiento molecular de la resistencia a antibióticos de importancia clínica en aislamientos recuperados en Cochabamba, Bolivia. Se estudiaron los genes codificantes de β-lactamasas de espectro extendido y de resistencia a quinolonas
Di Conza, José Alejandro, Gutkind, Gabriel Osvaldo, Radice, Marcela Alejandra, Saba Villarroel, Paola M.   +3 more
core   +1 more source

Broad-spectrum β-lactamases among Enterobacteriaceae of animal origin: molecular aspects, mobility and impact on public health [PDF]

, 2010
Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases) have been frequently demonstrated in the microbiota of food-producing animals. This may pose a human health hazard since these genes may be present
Butaye, Patrick, Dewulf, Jeroen, Haesebrouck, Freddy, Herman, Lieve, Heyndrickx, Marc, Martel, An, Persoons, Davy, Smet, Annemieke   +7 more
core   +1 more source

Do CTX-M  -lactamases hydrolyse ertapenem? [PDF]

Journal of Antimicrobial Chemotherapy, 2008
1. Martinez-Martinez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet 1998; 351: 797–9. 2. Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis 2006; 6: 629–40. 3. Yamane K, Wachino J, Suzuki S et al.
D. Girlich, L. Poirel, P. Nordmann
openaire   +1 more source

The Distribution of ESBL-Producing Enterobacteriaceae: Leicestershire UK Compared to Worldwide [PDF]

, 2019
open access ...
Reid, R., Samarasinghe, S., Varnakulasingam, Atheena   +2 more
core   +1 more source