Results 61 to 70 of about 71,036 (261)

Different factors associated with CTX-M-producing ST131 and non-ST131 Escherichia coli clinical isolates. [PDF]

PLoS ONE, 2013
OBJECTIVES: To determine factors associated with CTX-M-producing ST131 Escherichia coli which is the worldwide predominant lineage among CTX-M-producing E. coli isolates. METHODS: Consecutive inpatients with a clinical sample positive for CTX-M-producing
Marie-Hélène Nicolas-Chanoine, Jérôme Robert, Marie Vigan, Cédric Laouénan, Sylvain Brisse, France Mentré, Vincent Jarlier, Coli β study group   +7 more
doaj   +1 more source

Predictors of blaCTX-M-15 in varieties of Escherichia coli genotypes from humans in community settings in Mwanza, Tanzania [PDF]

, 2016
Extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae commonly cause infections worldwide. Bla CTX-M-15 has been commonly detected in hospital isolates in Mwanza, Tanzania. Little is known regarding the faecal carriage of ESBL isolates and
Can Imirzalioglu, Jeremiah Seni, Linda Falgenhauer, Mariam M. Mirambo, Martha F. Mushi, Mecky Matee, Nyambura Moremi, Rechel Julius, Stephen E. Mshana, Trinad Chakraborty   +9 more
core   +2 more sources

CTX-M-14, a Plasmid-Mediated CTX-M Type Extended-Spectrum β-Lactamase Isolated from Escherichia coli [PDF]

Antimicrobial Agents and Chemotherapy, 2002
ABSTRACT Four Escherichia coli isolates harboring CTX-M-14, with a single Ala231→Val substitution compared to CTX-M-9, had three different ribotypes. Cefotaxime resistance was plasmid encoded and conjugatively transferable.
L, Ma, Yoshikazu, Ishii, Feng-Yee, Chang, Keizo, Yamaguchi, Monto, Ho, L K, Siu   +5 more
openaire   +2 more sources

Potent and Selective IGF‐IIR‐Recruiting Bifunctional Molecules for Targeted Lysosomal Degradation of Extracellular and Membrane Proteins

Advanced Science, EarlyView.
Lysosome‐targeting chimeras (LYTACs) enable degradation of extracellular and membrane proteins via lysosomal trafficking. We report a novel IGF‐II mutant (Del1–7, Y27L) that selectively engages IGF‐IIR while avoiding IGF‐IR and IR‐A. mutIGF‐II–based LYTACs enhance target internalization and degradation and support a genetically encodable, all‐protein ...
Yuan Zhao, Yaxian Liao, Pengyun Li, Regina Stasser de Gonzalez, Xuankun Chen, Nicholas S. Nieto, Florence M. Brunel, Nick Cox, Joseph Stock, Matthew McHenry, Guangsen Fu, Penghsuan Huang, Wenxin Wu, Deqin Cai, Lingjun Li, Alexander N. Zaykov, Weiping Tang   +16 more
wiley   +1 more source

Identificación por PCR-SSCP de genes de cefotaximasas en aislamientos hospitalarios de Enterobacteriaceae

Revista Colombiana de Biotecnología, 2009
Las cefotaximasas (CTX-M) son las beta-lactamasas de espectro extendido más ampliamente diseminadas entre especies de la familia Enterobacteriaceae, y son la causa principal de resistencia en aislamientos causantes de infección intrahospitalaria.
José Ramón Mantilla Anaya, Emiliano Barreto Hernández, María Teresa Reguero Reza, Daniel Augusto Velandia Rodríguez   +3 more
doaj   +2 more sources

Characterizations of blaCTX–M–14 and blaCTX–M–64 in a clinical isolate of Escherichia coli from China

Frontiers in Microbiology, 2023
Extended-spectrum beta-lactamase-producing Gram-negative bacteria are common in the community and hospitals. To monitor ESBLs mediated by the CTX-M genotype, we collected clinical ESBL pathogenic strains from a hospital in central China and observed a ...
Mingxing Yang, Dong Liu, Xiaoquan Li, Chuting Xiao, Yingge Mao, Jiaqi He, Jiao Feng, Li Wang   +7 more
doaj   +1 more source

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae [PDF]

, 2018
Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which
Cebrero Cangueiro, Tania, Cordero Matia, María Elisa, Labrador Herrera, Gema, Smani, Younes, Álvarez Marín, Rocío   +4 more
core   +1 more source

SpaMode: A Broadly Applicable Framework for Deciphering Spatial Multi‐Omics Using Multimodal Mixture of Disentangled Experts

Advanced Science, EarlyView.
SpaMode introduces a versatile framework for spatial multi‐omics integration across vertical, horizontal, and mosaic scenarios. By disentangling modality‐invariant and variant features through a mixture‐of‐experts mechanism, it adaptively reconfigures spatially heterogeneous signals.
Xubin Zheng, Xinlei Huang, Xiang Zhou, Dian Meng, Ziyue Qiao, Zhiyuan Yuan, Lixin Cheng   +6 more
wiley   +1 more source

Molecular characteristics of extended-spectrum β-lactamases in clinical isolates from Escherichia coli at a Japanese tertiary hospital.

PLoS ONE, 2013
The prevalence of ESBL has been increasing worldwide. In this study, we investigated the molecular characteristics of ESBL among clinical isolates of Escherichia coli from a Japanese tertiary hospital.
Hisakazu Yano, Mina Uemura, Shiro Endo, Hajime Kanamori, Shinya Inomata, Risako Kakuta, Sadahiro Ichimura, Miho Ogawa, Masahiro Shimojima, Noriomi Ishibashi, Tetsuji Aoyagi, Masumitsu Hatta, Yoshiaki Gu, Mitsuhiro Yamada, Koichi Tokuda, Hiroyuki Kunishima, Miho Kitagawa, Yoichi Hirakata, Mitsuo Kaku   +18 more
doaj   +1 more source

Dissemination and characterization of plasmids carrying oqxAB-bla CTX-M genes in Escherichia coli isolates from food-producing animals. [PDF]

PLoS ONE, 2013
BACKGROUND: The association of PMQR and ESBLs in negative-bacteria isolates has been of great concern. The present study was performed to investigate the prevalence of co-transferability of oqxAB and bla CTX-M genes among the 696 Escherichia coli (E ...
Bao-Tao Liu, Qiu-E Yang, Liang Li, Jian Sun, Xiao-Ping Liao, Liang-Xing Fang, Shou-Shen Yang, Hui Deng, Ya-Hong Liu   +8 more
doaj   +1 more source