Results 71 to 80 of about 71,036 (261)

Faecal carriage of ESBL producing and colistin resistant Escherichia coli in avian species over a 2-year period (2017-2019) in Zimbabwe

Frontiers in Cellular and Infection Microbiology, 2022
IntroductionExtended spectrum beta-lactamase (ESBL) producing Escherichia coli have become widespread among food producing animals. These strains serve as a reservoir of antibiotic resistance genes (ARGs) and act as a possible source of infection to ...
Faustinos Tatenda Takawira, Faustinos Tatenda Takawira, Johann D. D. Pitout, Johann D. D. Pitout, Gaetan Thilliez, Tapfumanei Mashe, Tapfumanei Mashe, Ana Victoria Gutierrez, Robert A. Kingsley, Gisele Peirano, Jorge Matheu, Stanley Munyaradzi Midzi, Lusubilo Witson Mwamakamba, David L. Gally, Andrew Tarupiwa, Leckson Mukavhi, Marthie M. Ehlers, Marthie M. Ehlers, Sekesai Mtapuri-Zinyowera, Marleen M. Kock, Marleen M. Kock   +20 more
doaj   +1 more source

Detection of extended spectrum B-lactamases in urinary isolates of Klebsiella pneumoniae in relation to Bla SHV, Bla TEM and Bla CTX-M gene carriage [PDF]

, 2011
Background: Resistance to contemporary broad-spectrum β-lactam antibiotics mediated by extended-spectrum β-lactamases (ESBLs) is increasing worldwide.
Eftekhar, F., Golalipoor, M., Mansoursamaei, N., Rastegar, M.   +3 more
core   +1 more source

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]

, 2014
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D., Fitzgerald, Gerald F, Fouhy, Fiona, Ross, R Paul, STANTON, CATHERINE   +4 more
core   +1 more source

Primary Tumor Resection in Patients With Unresectable Metastatic Colorectal Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
This systematic review and meta‐analysis evaluated the role of primary tumor resection (PTR) in asymptomatic patients with unresectable metastatic colorectal cancer. Across 17 eligible studies including 9317 patients, PTR did not improve overall or progression‐free survival compared with chemotherapy alone.
Junpei Takashima, Hirotoshi Kobayashi, Daisuke Fujimoto, Fumihiko Miura   +3 more
wiley   +1 more source

Characterization of Environmental CTX-M-15-Producing Stenotrophomonas maltophilia [PDF]

Antimicrobial Agents and Chemotherapy, 2014
Stenotrophomonas maltophilia is a widespread environmental microorganism that has emerged as a significant opportunistic pathogen due to its intrinsic resistance to almost all available antibiotics. Forty-one S. maltophilia isolates were recovered from retail shellfish (Mytilus galloprovincialis ; 8 isolates) purchased at fish markets in Split, Croatia,
Maravić, Ana, Skočibušić, Mirjana, Fredotović, Željana, Cvjetan Čutura, Svjetlana, Šamanić, Ivica, Puizina, Jasna   +5 more
openaire   +3 more sources

Multifunctional hyaluronic acid hydrogel integrating exosome‐encapsulating gelatin microspheres accelerates skeletal muscle regeneration via TGF‐β1 activation and enhanced myogenic cell viability

BMEMat, EarlyView.
Schematic illustration of preparation of injectable H/G@Co@miR‐206 hydrogel for efficient skeletal muscle regeneration in cardiotoxin‐induced skeletal muscle injury SD rat model. Abstract The effective treatment of acute skeletal muscle injuries remains challenging, necessitating therapeutic strategies that concurrently reestablish vascular perfusion ...
Zhengzhe Han, Zongyue Li, Ang Li, Zheng Jiang, Saiyu Shi, Zhipeng Wang, Jishizhan Chen, Yun Qian, Yuanyang Gu, Xianyou Zheng   +9 more
wiley   +1 more source

Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates [PDF]

, 2013
Antibiotic resistance is one of the main problems concerning public health or clinical practice. Antimicrobial peptides appear as good candidates for the development of new therapeutic drugs.
Corso, Alejandra, Faccone, Diego Francisco, Maffia, Paulo Cesar, Martínez, Melina María Belén, Noguera, Martín Ezequiel, Payés, Cristian, Semorile, Liliana Carmen, Veliz, Omar   +7 more
core   +1 more source

Denosumab Offers Relatively Lower Initial Protection Against Osteoporotic Vertebral Fractures in Treatment‐Naive Patients Compared With Zoledronate

Clinical Pharmacology &Therapeutics, EarlyView.
We compared the initial efficacy of denosumab (Dmab) and zoledronate (ZOL) in treatment‐naive patients with osteoporosis. This cohort study, based on TriNetX data, evaluated the risks of fractures and mortality using Kaplan–Meier survival analyses, with hazard ratios (HRs) and 95% confidence intervals (CIs).
Ko‐Hsiu Lu, Shiow‐Ing Wang, Shun‐Fa Yang   +2 more
wiley   +1 more source

Extended-spectrum beta-lactamase-producing bacteria are not detected in supragingival plaque samples from human fecal carriers of ESBL-producing Enterobacteriaceae [PDF]

, 2014
Background: The prevalence of infections caused by Cefotaximase-Munich (CTX-M)-type extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) has rapidly increased during the past 15 years.
Arne Søraas, Arnfinn Sundsfjord, Ingar Olsen, Ola Bjørang, Pål Arne Jenum, Trude Handal   +5 more
core   +2 more sources

Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?

Clinical Pharmacology &Therapeutics, EarlyView.
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu, Renn‐Chia Lin, Ing‐Lin Chang, Shau‐Huai Fu, Meng‐Ying Tsai, Shun‐Fa Yang   +5 more
wiley   +1 more source