Results 21 to 30 of about 292 (109)

Joint-tissue integrative analysis identifies high-risk genes for Parkinson’s disease [PDF]

Frontiers in Neuroscience
The loss of dopaminergic neurons in the substantia nigra and the abnormal accumulation of synuclein proteins and neurotransmitters in Lewy bodies constitute the primary symptoms of Parkinson’s disease (PD).
Ya-Shi Wu, Ya-Shi Wu, Wen-Han Zheng, Tai-Hang Liu, Yan Sun, Yu-Ting Xu, Li-Zhen Shao, Qin-Yu Cai, Ya Qin Tang   +8 more
doaj   +2 more sources

Ciguatoxin Detection in Flesh and Liver of Relevant Fish Species from the Canary Islands. [PDF]

Toxins (Basel), 2022
The Canary Islands are a ciguatoxin (CTX) hotspot with an established official monitoring for the detection of CTX in fish flesh from the authorised points of first sale. Fish caught by recreational fishermen are not officially tested and the consumption
Ramos-Sosa MJ, García-Álvarez N, Sanchez-Henao A, Silva Sergent F, Padilla D, Estévez P, Caballero MJ, Martín-Barrasa JL, Gago-Martínez A, Diogène J, Real F.   +10 more
europepmc   +3 more sources

Detection of Ciguatoxins and Tetrodotoxins in Seafood with Biosensors and Other Smart Bioanalytical Systems. [PDF]

Foods, 2023
The emergence of marine toxins such as ciguatoxins (CTXs) and tetrodotoxins (TTXs) in non-endemic regions may pose a serious food safety threat and public health concern if proper control measures are not applied. This article provides an overview of the
Reverté J, Alkassar M, Diogène J, Campàs M.   +3 more
europepmc   +3 more sources

Targeted Metabolite Fingerprints of Thirteen Gambierdiscus, Five Coolia and Two Fukuyoa Species. [PDF]

Mar Drugs
The genus Gambierdiscus produces an array of bioactive hydrophilic and lipophilic secondary metabolites that range in mode of action and toxicity. In this study, the metabolite fingerprint was mapped for thirteen Gambierdiscus, five Coolia and two ...
Murray JS, Passfield EMF, Rhodes LL, Puddick J, Finch SC, Smith KF, van Ginkel R, Mudge EM, Nishimura T, Funaki H, Adachi M, Prinsep MR, Harwood DT.   +12 more
europepmc   +3 more sources

In silico simulations and functional cell studies evidence similar potency and distinct binding of pacific and caribbean ciguatoxins [PDF]

, 2022
Ciguatoxins (CTX) cause ciguatera poisoning, which is the most common reported human food poisoning related to natural marine toxins. Pacific ciguatoxins are the most abundant and studied CTX analogues; however, the growing distribution of Caribbean ...
Botana López, Luis Miguel, Castro Alonso, David Miguel, Estévez Bastos, Pablo, Gago Martínez, Ana, González Bello, Concepción, Lence Quintana, Emilio José, Leão, José Manuel, Louzao Ojeda, María Carmen, Raposo García, Sandra   +8 more
core   +1 more source

Ciguatoxin-like toxicity distribution in flesh of amberjack (Seriola spp.) and dusky grouper (Epinephelus marginatus) [PDF]

, 2023
Ciguatoxins (CTXs) are marine neurotoxins that cause ciguatera poisoning (CP), mainly through the consumption of fish. The distribution of CTXs in fish is known to be unequal. Studies have shown that viscera accumulate more toxins than muscle, but little
Caballero, María José, Diogène, Jorge, Fernández, Antonio, Gago-Martínez, Ana, García-Álvarez, Natalia, Padilla, Daniel, Ramos-Sosa, María José, Real, Fernando, Sanchez-Henao, Andres, Silva Sergent, Freddy   +9 more
core   +1 more source

Determination of the toxicity equivalency factors for ciguatoxins using human sodium channels [PDF]

, 2022
Ciguatoxins (CTXs) which are produced by dinoflagellates of the genus Gambierdiscus and Fukuyoa and share a ladder-shaped polyether structure, are causative compounds of one of the most frequent foodborne illness disease known as ciguatera fish poisoning
Botana López, Luis Miguel, Fuwa, Haruhiko, Louzao Ojeda, María Carmen, Raposo García, Sandra, Sasaki, Makoto, Vale González, María del Carmen   +5 more
core   +1 more source

Ciguatera Mini Review: 21st Century Environmental Challenges and the Interdisciplinary Research Efforts Rising to Meet Them. [PDF]

Int J Environ Res Public Health, 2021
Globally, the livelihoods of over a billion people are affected by changes to marine eco-systems, both structurally and systematically. Resources and ecosystem services, provided by the marine environment, contribute nutrition, income, and health ...
Loeffler CR, Tartaglione L, Friedemann M, Spielmeyer A, Kappenstein O, Bodi D.   +5 more
europepmc   +3 more sources

Analytical Studies on Ciguateric Fish in Okinawa, Japan (II): The Grouper Variola albimarginata

Journal of Marine Science and Engineering, 2023
Ciguatera fish poisoning (CFP) refers to an illness caused by ingesting fish that have accumulated ciguatoxins (CTXs). CFP frequently occurs in the tropical and subtropical Indo-Pacific Ocean and the Caribbean Sea.
Naomasa Oshiro, Hiroya Nagasawa, Mio Nishimura, Kyoko Kuniyoshi, Naoki Kobayashi, Yoshiko Sugita-Konishi, Tsuyoshi Ikehara, Katsunori Tachihara, Takeshi Yasumoto   +8 more
doaj   +1 more source

An Extensive Survey of Ciguatoxins on Grouper Variola louti from the Ryukyu Islands, Japan, Using Liquid Chromatography–Tandem Mass Spectrometry (LC-MS/MS)

Journal of Marine Science and Engineering, 2022
Ingesting fish contaminated with ciguatoxins (CTXs) originating from epibenthic dinoflagellates causes ciguatera fish poisoning (CFP). CFP occurs mainly in the tropical and subtropical Indo–Pacific region and the Caribbean Sea.
Naomasa Oshiro, Hiroya Nagasawa, Miharu Watanabe, Mio Nishimura, Kyoko Kuniyoshi, Naoki Kobayashi, Yoshiko Sugita-Konishi, Hiroshi Asakura, Katsunori Tachihara, Takeshi Yasumoto   +9 more
doaj   +1 more source