Results 51 to 60 of about 16,034 (193)

Vaccarin Improves Myocardial Ischemia–Reperfusion Injury by Attenuating Oxidative Stress and Ferroptosis Through Reducing NOX4‐Modulated JAK2/STAT3 Pathway Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vaccarin is a naturally occurring flavonoid glycoside with cardioprotective properties; however, its involvement in myocardial ischemia–reperfusion (MI/R) injury remains poorly defined. We herein investigated whether vaccarin protects cardiomyocytes from MI/R‐induced dysfunction in vivo and in vitro and examined the associated molecular ...
Han Yang, Mi Zhou, Feng‐Cai Zhang
wiley   +1 more source

Mass Spectrometric Analysis of Cucurbitacins and Dihydrocucurbitacins from the Tuber of Citrullus naudinianus

Biomolecules, 2023
The vast pool of structurally and functionally distinct secondary metabolites (i.e., natural products (NPs)) is constantly being expanded, a process also driven by the rapid progress in the development of analytical techniques. Such NPs often show potent
Moritz Benka, Kristof Görlitz, Michael C. Schöttgen, Simon Lagies, Daniel A. Mohl, Michel Kather, Iwanette Du Preez-Bruwer, Davis Mumbengegwi, Robin Teufel, Stefanie Kowarschik, Roman Huber, Dietmar A. Plattner, Bernd Kammerer   +12 more
doaj   +1 more source

Pedunculoside Inhibits Hepatocellular Carcinoma Progression by Activating the MAPK Signaling Pathway Through Targeting and Suppressing CDK4

Phytotherapy Research, EarlyView.
Pedunculoside targets and suppresses CDK4; consequently, it activates the MAPK pathway and inhibits hepatocellular carcinoma progression. ABSTRACT Hepatocellular carcinoma (HCC) remains a major challenge in cancer prevention and treatment, highlighting the urgent need for effective and low‐toxicity anti‐HCC therapies. Recently, CDK4‐targeted inhibitors
Yang Zhou, Jingyun Chi, Yuan Ding, Zhidi Zhang, Rui Liang, Tianhao Wang, Yan Jiang, Rujun Song, Huazhou Fu, Xizhen Zhou   +9 more
wiley   +1 more source

The cytotoxic Activity of Cucurbitacin E and Busulphan on ovarian and stomach cancer cells in vitro : a comparative study [PDF]

, 1996
A comparative study of the cytotoxicity of cucurbitacin E, a natural product, and busulphan on human ovarian and stomach cell lines was carried out.
Attard, Everaldo, Cuschieri, Alfred, Grixti, Mario, Scicluna-Spiteri, Anthony   +3 more
core  

Development of an Artificial Liquid Diet for Allelochemical Delivery in Lycorma delicatula

Journal of Applied Entomology, EarlyView.
ABSTRACT Spotted lanternfly, Lycorma delicatula White (Hemiptera: Fulgoridae), is an invasive phloem‐feeding planthopper native to Asia, which poses a growing threat to US agriculture due to its broad host range and rapid spread since its 2014 detection. To better understand how L.
Brian F. Ruether, Mariana Gelambi, Kate A. Burgiss, Alejandra Caballero, Sherry B. Hildreth, Dorothea Tholl   +5 more
wiley   +1 more source

A promising biotechnical approach to pest management of the western corn rootworm in Illinois maize fields shielded with a MCA kairomone baited trap line [PDF]

, 2008
The leaf beetle Diabrotica virgifera virgifera (Coleoptera: Chrysomelidae), (D.v.v.), also called the western corn rootworm, is endemic to the New World and ranks among the top ten insect pests in worldwide grain production. D.v.v.
Hein, Detlef F., Hummel, Hans E., Shaw, John T.   +2 more
core  

Targeting tumor-associated macrophages by anti-tumor Chinese materia medica [PDF]

, 2017
Tumor-associated macrophages (TAMs) play a key role in all stages of tumorigenesis and tumor progression. TAMs secrete different kinds of cytokines, chemokines, and enzymes to affect the progression, metastasis, and resistance to therapy depending on ...
A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Mantovani, A Saccani, A Schmieder, A Sica, A Sica, B Ruffell, B Shao, BB Aggarwal, BC Kennedy, BK Sekhon, C Jia, C Liu, C Steidl, CE Lewis, CK Mueller, Curzio Rüegg, D Ghosh, DM Mosser, E Bolli, E Schutyser, F Li, F Zhao, FO Martinez, FR Zhao, G Shu, G Solinas, H Diao, H Fritz, H Kurahara, H Kurahara, H Ouyang, H Wang, H Wang, H Zhang, H Zhao, HYT Nguyen, IA Schepetkin, J Cook, J Deng, J Ding, J Gao, J Li, J Li, J Li, J Rius, J Wang, J Yin, J Zhang, JB Mitchem, JW Pollard, JY Jang, JY Shin, Kun Zhou, L Bingle, L Sanchez-Martin, L Varinska, LI Partecke, Li-kang Sun, Lin Miao, M Egeblad, M Hong, M Ito, M Jinushi, M Pesic, MA Khan, Margaret Gebauer, Micheal O. Hottiger, ML Taddei, MR Galdiero, Muriel Cuendet, MY Kim, P Allavena, P Suboj, P Sun, P Yu, PS Kyrn, Q Dong, Q Lin, R Graziose, R Noy, R Ostuni, R Zhu, S Banerjee, S Gao, S Iwanowycz, S Lunardi, S Shi, S Shimura, S Ye, SM Woo, SR Hingorani, SR Hyam, T Kawanishi, T Xu, V Riabov, W Lam, W Shi, Wei-ling Pu, X Jia, X Li, X Lin, X Nie, X Qian, X Sun, X Tang, X Wang, X Zhan, X Zhang, X Zhang, Xiu-mei Gao, XL Zhu, XW Yang, Y Cai, Y Kimura, Y Lei, Y Liu, Y Song, Y Tu, Y Wang, Y Wang, Y Zhao, YP Guo, Yun-sha Zhang, Z Cai, Z Jiang, Z Lin, Z Liu   +131 more
core   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, EarlyView.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Phytochemical Composition, Health Benefits, Functional Properties, and Food Applications of Pumpkin Seeds

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Pumpkin seeds (Cucurbita spp.) are rich in bioactive compounds including proteins, unsaturated fatty acids, dietary fiber, vitamins (E and B‐complex), minerals (zinc, magnesium, iron), and phytochemicals such as phenolics, flavonoids, and phytosterols.
Messenbet Geremew Kassa, Desye Alemu Teferi   +1 more
wiley   +1 more source